NEWS: Nurofen + etc to be made Prescription only!!!

[Mr Blonde]

OK on your recommendation I will now try second washing and DXM.

I don't know if for tolerance you use it every day, just when you dose which I guess is everyday for addicts. I heard you use 30mg before dosing the opioid, and it will prevent tolerance build up. I've heard conflicting reports on it though.

Damn morphine is good... :D

 

[TripppAR]

Ha ha .. you crazy kids!

I mixed DXM like an hour or so before hand one time and it was GREAT! I mean i had a really really ood buzz going! More then simple euphoria from the dean alone! Very enjoyable..

I got into DXM for a little bit last year when i discovered how easy it was to get... i figured i would get a bottle of that before they make it illegal or some bullshit haha..

If the media got hold of the cough syrup thing... they would destroy it! They enjoy killing fun. .And lying lol..

But yeh anyways im buzzing nicely off 500mg's .. went and picked up 2 packs of panafen + from 2 chemists... 30 packs!

 

[drug_mentor]

Mr Blonde, you might want to try second washing and using DXM seperately at first, just so you can objectively assess how effectively each one improves the experience, if at all, but I am betting they will!

 

[JoshE]

I wouldn't say that just yet, 8 Nurofens is a low dose in my opinion. I fucking love codeine now, but when I first used it I felt nothing off 120mg, had to try 240 to get the good feeling.

GurnEr joshE: Try using a higher dose and see if that works, I wouldn't put it down to enzymes just yet.

Ok will do, Thanks bro

 

[Mr Blonde]

Mr Blonde, you might want to try second washing and using DXM seperately at first, just so you can objectively assess how effectively each one improves the experience, if at all, but I am betting they will!

Good idea! I might try the second wash first and the DXM sometimes after that...

Actually since I have this morphine I might try the DXM next time I use that...

Ok will do, Thanks bro

No problems, let us know how it works out for you and if you find your sweet spot.

 

[L3inad]

Gah. I envy you guys so much its not even funny. My opiate experience extends only to a box of tramadol I got after my wisdom teeth =\

I just cant get anything out of codiene. I am one of the 7% of caucasians that are missing/lacking the enzyme, but even still Ive taken like ~400mg and not felt a damn thing! I should be able to metabolise at least a baseline dose shouldn't I?

Meh. Has anyone got any idea's on how to get past my enzyme difficulties?

And before anyone asks, yes I am 100% sure that I'm part of the 7%, a 24 hour DXM trip straight from hell ending in a rather confused and dissoriantated trip to the hospital on just 300mg has me pretty convinced lol.

Idea's would be appreciated as I'm taking a break from the bong for a while over exams and could really use another cheap and effective downer to get my by

 

[Mr Blonde]

^ Hey brother, there are a few substances which induce CYP2D6 converting more codeine into morphine, hold on a second while I get my CYP450 enzyme family chart...

 

[Mr Blonde]

OK here we go:

Carbamazepine - A prescription mood stabilizer and anticonvulsant.

Ethanol - Pretty rare around Australia these days

Phenobarbital - Rx only barbiturate, very rarely rx'd these days as benzos have taken their place.

Phenytoin - Antiepileptic, rx only I assume as well.

Primidone - Anticonvulsant, one of it's major metabolites is phenobarbital.

Rifampin - Antibiotic, rx only as well I assume.

Ritonavir - Antiretroviral, used to treat HIV/AIDS,

St John's wort - Commonly used as a herbal treatment for depression and anxiety, I must note here that I have seen conflicting articles on whether St John's induces or inhibits CYP2D6.

My advice would be ethanol and St John's Wort, both of which I have used a long time ago with codeine to potentiate. I can't remember how it went, but basically about 1 hour before the codeine take St John's Wort, take a recommended dose or somewhat higher. About 45 minutes before dosing drink a small amount of alcohol, maybe a glass of wine or a beer. See if this helps out a little bit.

 

[Crankinit]

I've always had the opposite effect with alcohol, even a drink or two before dosing the codeine completely prevents any kind of opiate buzz. I always figured it inhibited the enzyme.

 

[L3inad]

Hrmmm interesting. I will definately have to look into that more, but I'm pleased to see that there are options!

Sadly I dont have any of those scripts, nor can I think of anyone I know who does.

I might give the St johns wort a go, as its easy to get a hold of.

Booze I've tried, think I may have felt a slightly hazy and somewhat more relaxed then I should have been with the alcohol alone, but nothing significant.

Would any of the other potinators mentioned earlier in the thread such as restavit be of any help to me? Possibly in combination with St John's? I cant think of any bad interactions between st johns, doxy and codeine.

Also, would taking it in multiple doses (ie. say 100mg loading dose followed by 400mg at t +1h) increase metabolism considering my enzyme deficiency and that metabolism is meant to increase over time? Or is that tramadol I'm thinking of? Opiates are not my forte by any means.

 

[Mr Blonde]

^ Redosing doesn't work for most people because codeine inhibits the enzyme that converts it to morphine. So in your case probably won't help much.

How did you use the alcohol with codeine? If I drink during the high I hate it, but if I drink one drink beforehand it does make me feel pretty good. Otherwise I'm just ruining the buzz.

As for potentiators such as antihistamines, they really only would work well if you are getting a decent dose first. They work by adding sedation to the experience as well as reducing the itchiness. Technically they don't really potentiate the codeine, they just make it more enjoyable some people find.

A true potentiator for codeine would be one of those inducers I mentioned which increases the amount of morphine you get out of a dose.

 

[L3inad]

I had approximately 3 standard drinks over the course of an hour or so starting at the same time as dosing the codiene. I figured that'd be best as codeine takes a while to metabolise into the good stuff and alcohol leaves me feeling rather seedy in a very short space of time so I tried to time it so the codeine would kick before the seedy feeling hit, no success.

I do find that just codeine by itself then smoking a couple bowls does result in a pleasant but extremely mild body high, but thats about the best I've ever gotton out of it =\ And thats not an issue of potination more so synergy.

I will give the St johns a whirl and report back.

Really, this is frustrating because Ive never experienced a full blown opiate high. Even with the tramadol I didnt want to push it to far because of the whole seizure thing, it was nice but left me feeling that theres alot more to the experience that I didnt get.

If I cant get success with codeine I might have to be naughty and have a sample of some endone just to see what I'm missing out on.

 

[Mr Blonde]

^ Yeah endone is cool. :D

You probably drank a little too much and at the wrong time, it should be a little while before dosing so that the CYP2D6 enzymes are primed and ready to go, I don't know about other people here but I feel my codeine relatively quickly after I dose it doesn't take that long to start metabolizing.

I don't know about opioids and weed I've heard mixed reports and I'm not allowed to smoke weed anymore because it makes me psychotic.

 

[drug_mentor]

I ALWAYS consume 1 or 2 standard measures of spirits (whisky or bourbon) mixed with either lemonade or coke in the half hour or so before I dose my codeine, trying to finish atleast 5, if not 10 minutes before dosing.

I may have to try St Johns Wort although I am apprehensive because on principle I have always avoided MAOIs. Weed goes excellent with codeine, the only reason I would ever do codeine and not smoke weed is if I had to avoid it because of drug tests. It really synergises well with the high and if I had to choose only one drug to combine with codeine ever again it would be marijuana.

 

[Mr Blonde]

^ St John's Wort is only a mild MAOI though, not that I would risk a contraindicated combination still.

Marijuana I avoid like the plague due to mental health reasons. And I don't do the alcohol combo much anymore, don't really know why..

 

[rolls_]

I was logged in under a silenced account so half my posts in this thread didn show up so just reposting a couple of them that were directed at mr blonde.

Try using two coffee filters, that's what I used to do.

Or use a 2xmicrofibre sunglasses bag, you can squeeze it with both hands, filters in under a minute and the solution is crystal clear

^ Too much.

It was about seven dollars at least for each pack, got six. I will definitely have to take a break.

Oh yeah and no one would sell me 40 packs. Fuckers.

Could always order online, loads of online pharmacies. Just give a name and address, then next time sign up with the same address but make it 15a or 15b, if theres only address 15 the posties will always deliver it there.

I used to do that to scam free samples lol. Ordered every single letter from a to k lol.

Whilst the above would probably work, probably a sign to cut down. You never answered me before, you considered suboxone?

That's it, fuck codeine I'm moving on to IV morphine.

Slippery slope man, you sure you really want to do that?

Buprenorphine, its cheap and legal if you see an addiction specialist. You can also have whatever dose you want daily for the same price.

The aim is to get you clean but if you find it helps control your bipolar most of them will let you stay on it for a few years.

 

[Mr Blonde]

^ Hey rolls, yeah I have been thinking about buprenorphine as I can't afford to keep using like I am.

I went through all the morphine last night, I had a really stressful day and ended up using it until 4 am this morning then crashed out, woke up feeling like shit.

I might try the sunglasses bag trick, thanks.

 

[DoctorShop]

Seriously. Fuck all this codeine shit.

If you can cut it lose, do so now.

Otherwise, get on the done or subbies and bring yourself down gradually.

 

[L3inad]

Okay. So in an effort to get past this shitty enzyme thing, I have done the following -

T + 0 hours - Dosed 2 tablets of St Johns wort (said to take one 3 times a day)

T + 15 min - Consumed 30ml (1 Standard drink) of vodka

T + 30 min - Consumed a further 15ml of Vodka (Running total at 1.5 Standard drinks)

T + 1 hour - Dosed 450mg of codeine, accounting for loss in extraction I'd say its upwards of 350mg (I do temp checks)

That was 15 mins ago, lets see where that gets me. If 450mg and two potinators doesnt get me off I dont know what will lol

I shall return later to share how it went, because I know you all care so much =P

 

[drug_mentor]

^ Best of luck there mate, hope it goes well.

Sunglasses bag is an interesting idea rolls, I might have to give that one a try. Lately I have been consuming more codeine more often and am a little concerned more shite is getting through than is particularly good for my wellbeing, if that gets it crystal clear it would be a worthwhile investment.