Fertile
Bluelighter
- Joined
- Mar 31, 2022
- Messages
- 1,627
You misunderstand - in no toxicology test will any research body accept 'well it's less toxic than heavy alcohol use;. The test is an absolute.
Now, if it can be shown that just 1 kavalactone is responsible for the increased risk, as long as it's not vital for subjective effects then it can be omitted. It's just that I do not see any studies in which each of the actives are tested.
But as things stand, it's very easy for a government body to simply ban the product. It seems to me like it could be a good, safe alternative but a medicine (for example) would not be licenced if it had the potential to cause liver damage. Just what that damage IS would say a lot. I mean, there are MANY medicines out there that carry such risks and for those, regular liver function tests are carried out.... but this is hardy practical.
Chemically they are only modestly complex, the pain being that several are chiral. In fact, it looks like several of them can actually swap from R to S and maybe that is the source of toxicity i.e. when fresh and natural, it's safe but stored for a long time, it's not.
Believe me, I would LOVE this to be legal but it has to be a natural compound (or at least it has to be found naturally) but long experience has taught me that the BEST way to stay under the wire is happy, healthy customers.
I mean, wouldn't it be lovely if one could extract khat and make it into a vape! Vape technology is maturing but people simply will not pay huge sums and so you need to keep a close eye on costs.
Now, if it can be shown that just 1 kavalactone is responsible for the increased risk, as long as it's not vital for subjective effects then it can be omitted. It's just that I do not see any studies in which each of the actives are tested.
But as things stand, it's very easy for a government body to simply ban the product. It seems to me like it could be a good, safe alternative but a medicine (for example) would not be licenced if it had the potential to cause liver damage. Just what that damage IS would say a lot. I mean, there are MANY medicines out there that carry such risks and for those, regular liver function tests are carried out.... but this is hardy practical.
Chemically they are only modestly complex, the pain being that several are chiral. In fact, it looks like several of them can actually swap from R to S and maybe that is the source of toxicity i.e. when fresh and natural, it's safe but stored for a long time, it's not.
Believe me, I would LOVE this to be legal but it has to be a natural compound (or at least it has to be found naturally) but long experience has taught me that the BEST way to stay under the wire is happy, healthy customers.
I mean, wouldn't it be lovely if one could extract khat and make it into a vape! Vape technology is maturing but people simply will not pay huge sums and so you need to keep a close eye on costs.