I honestly do no know, I can only imagine mixing anything usually doesn't end up the way you want it too. I had a bad experience 2 days ago from mixing xanax and opioids. Almost died. Just be careful man and welcome to bluelight. take in all the good info you can. here is something you can read from me and comment if you want. its informative and may help one day in the future if you decide to think about doing something dumb like me.-----> http://www.bluelight.org/vb/threads...-Water-Extraction-with-Tylenol-3-s?p=13392972