needinfo on quitting hydro painkillers.

[hvac5646]

^ more so your kidneys and GI system.

kidneys....prob too..I guess am falling apart.

 

[adder]

I was careful with my phrasing when I referenced use for maintenance and utilizing the blockade effect. Lower doses most certainly are useful and often sufficient for detox or withdrawal-cessation but won't provide many of the advantages that clinicians and addicts alike seek.

Many users here will testify that they prefer doses smaller than 2mg SL qd however the reason that larger doses are preferred clinically is because its easier to produce stable plasma levels with once-daily administration and utilize buprenorphine's ability to block the effects of other opioids. You'll notice many here who do maintain on <2mg often split their doses.

In addiction treatment, you want to move people away from use that wears off and move them away from focusing on using substances so its preferred that people take it once a day and establish doses where there is next to little-to-no fluctuation in plasma levels so they never start to feel sick, never feel relief or high from their maintenance meds, etc.

Its not a perfect system for everyone, but this is essentially the philosophy behind once-daily administration of high(er) dose buprenorphine used for maintenance.

I know exactly what you mean. Like I said, I can't imagine buprenorphine as a taper-down drug for myself. However, I used it as a maintenance drug and the good dose was 16-24mg, then after like 3 days I would totally not need to dose again on the following day after 24hrs passed. I did because I knew I had to but buprenorphine definitely eats methadone for breakfast concerning saturating effect. I could go on bupe without redosing for around 30 hours without feeling any withdrawal effects. But I needed sth to taper down then and bupe let me down here. But it was just at the beginning of my only-maintenance-opioids ride (it's been 21 months now...). Now I take my methadone dose at 12pm and I wake up sick on the following day in the morning (but I couldn't care less now as I'm tapering down and I'm on 15ml now so it's pain no matter what).