I have used 25i-NBOMe more then any other psychedelic. reason being, i have a supply that wont being ending anytime soon. I use it maybe twice a month at most. Sometimes ill take 30mg of temazepam if i cant sleep afterwords. Ive never had a problem. I usually dont find that 25i prevents me from sleeping however. sometimes ive actually noticed slight fatigue while on it.
I wouldnt worry about the mix. certainly shouldnt have any negative effects, except for lessening any remaining effects of 25i
lsd is another story, i cant sleep even with 60mg of temazepam and 2mg of xanax.