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Nausea reduction 2c-xx? problem solved!

PhyllipThylamine

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Feb 5, 2011
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322
Nausea on 2c-xx compounds? My problem solved!

Having experimented with 2c-t-2, 2c-e & 2c-c on a number of occasions in recent years & had trouble with the bodyload on all three, I had become less inclined to continue using these facinating compounds because of the nausea. Despite long fasting prior to each trip on any of these 2c's, I've found the nausea to be debelitating on occasion, & at the very least, irritating & distracting.

My first trip was the best for nausea & it's only after some time that I've worked out why. I had not eaten since the evening before, a cereal around 10pm & ingested 10mg of t-2 at around 9:30 on a Sat morning last summer, followed an hour later by 5mg. Come-up was quite smooth outdoors in the park, & the trip long & enjoyable. After a couple of 2c-e trips & a couple of 2c-c trips (more on these later) I tried t2 again, late last year, this time ingesting 15mgs in one go in the morning after the same fasting regime. I enjoyed this trip once it got going, but I had some serious nausea on the come-up & wasnt able to go outside, which I really enjoy doing at the start of or during a trip.

The intervening 2c-e trips were less nauseating but less intence than the t2. Both occasions were at 12mgs so I'm looking to increase my dosage of this chem, next time I try it. My trip-partner, who has enojoyed all the same experiences AND side-effects as I have, seemed to trip harder on the 2c-e than I did on both occassion. This is quite rare & I'm usually the sensitive one when it comes to tripping & chemicals in general.

My two 2c-c trips are the ones that have caused me the most uncomfortable nausea & I found this very disapointing. The shorter trip on 2c-c makes it a handy little midweek traveller, or one for when you need to be less or un-hungover the nest day. I also like long daytime trips & short evening ones. I rarely stay out or up all night these days, bit long in the tooth for that shit... Anyway, I digress. I had thought 2c-c would end up my favourite of the family. The first 2c-c trip was 20mg, in the evening about 8 hours after lunch. Barely threshold dose, I know but I'm sensitive. Despite the rather powerful urge to spew for the first 40 mins or so I enjoyed a pleasant, mild 2 hour trip. I was eager to increase the dose & felt that perhaps the strength of a larger dose would overpower the nausea. Not so. Next dose was 25mg, in the evening under the same circumstances. This time the nausea was awful, lasted well into the trip & affected it negatively. It got so bad that I insufflated a line of a mild stimulant that eased the nausea but killed the trip too... VERY disapointing.

However, over the last month of so, I've been enjoying Methoxetamine at the wknds & havent bothered looking at the 2c's... & perhaps this gave me time to put 2 & 2 together, so to speak Lol I realised that my initial STAGGERED dose of t2 may have been less nauseating because the drug came on slower that way... The exact same dose, all in one go was MUCH more illing!

So last Friday I upped the 2c-c dose to 35mgs but ingested sublingually (avoiding the old stomach as best as I could) & in staggered the doses. 15mgs, followed each half hour by 10mg until the 35mgs was gone. This was BRILLIANT! I got a proper trip from the 2c-c for the first time, bit longer than usual but still short (3 hours max) but strong, with swirling colours, tracers, embossment, depth & great movement in stationary objects. My trip-partner & I laughed our arses off & had a great evening scrolling the net for fractals & listening to Bauhaus (& later watching a Bauhaus live DVD!). There was only the mildest, briefest spell of nausea, & I think this was mainly because I couldnt keep the last dose in my mouth coz it was vile Lol I had to swallow Lol

So, for anyone who enjoys 2c's but gets nasty nausea on them, please try breaking your doses into smaller amounts & easing into it. I'm going to experiment with the 2c-t-2 & the 2c-e in a similar way, possible increasing the doses slightly with each.

Happy Travels!
Love Phyl :)
 
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personally i'm not getting nauseous on 2c-e anymore... the first few times i did because i was nervous, but it always dissipated after smoking some nice weed...

now i'm getting an incredibly goodfeeling body-buzz of 2c-e and nothing in the way of nausea... but if i would, weed would be my choice for curing it ;)
 
weed is always used with trippings & if a certain chem didnt work with herb I probably wouldn't take it.

For the record, weed was smoked during & before all of the above experiments & I probably shoulda mentioned that, sorry. I've also taken various anti-emetic medicines & nothing worked except for the staggered dosing thing. I'm really grateful that I put this together because I love this group of chems & was getting a bit sad that I couldnt enjoy them properly. When shrooms were being legally sold in London I got quite used to tripping pretty regularly, then the c**ts banned them &, by some coincidence, my regular trip partner moved away... Discovering the 2c series has made regular tripping available to me again, providing I stagger my dosing thus avoiding the nausea.
 
smoking weed is not always available to all, also for some it increases anxiety, or confusion, and some, myself included, find that it can take a little detail from the trip itself (i much prefer the lucidity).

that being said, staggering doses does work, at least for 2c-c (though i must admit it isnt one of the most nauseating chems out there), but some experimentation is needed, because everyone is different (for instance, i get very is any nausea from shrooms, while 2ct2 absolutely empties me, staggered or not).

i was hoping for a more chemical approach to solving the nausea problem :P
 
Plugging it requires about the same dose as snorting, and hits in 10 minutes without nausea.

Also on 2c's its usually only just my back being a little tense that bothers me at all.
 
^my first time plugging 2c-e, i puked in 5 minutes.

I agree that speed of come-up can be related to intensity of body-load. Why do you think so many people puke from snorting 2C-X even though the chemical should not be ending up in the stomach itself?

Staggered dosing is PERFECT for easing bodyload.
In fact that is exactly how I introduced my friend to 2C-I.
We each had 4mg oral to start, then at T+1.5 we each had an additional 18-20mg.
The come-up was smooth, enjoyable, and nobody blew chunks! Of course, we also had copious weed and beer, so whatever.

As for a more chemical approach to the nausea: some people find that diphenhydramine (benadryl, unisom) or dimenhydrinate (dramamine) work wonders for reducing sweaty stimulation and also calming the tummy. but other people do not respond in the same way.
 
I like snorting small amounts (~8mg) of 2c-e best. I usually take snort 8mg every few hours until I'm ready to go to bed. Very little nausea and a pretty intense trip after the initial burning sensation.
 
?! how on earth do yo consider 8mg of 2C-E to be "small amounts" just before bed?

the intense body sensations and bright visuals make it completely impossible for me to fall asleep on 2C-anything! so either you're spending the night tripping instead of sleeping (and then what do you do in the morning when you have to go to work/school completely exhausted?)... or your body is so tolerant to the effects of 2C-E that you do actually just sleep, and "waste" such a powerful opportunity for a trip.

8mg snorted 2C-E is in full +++ territory for me.
 
I won't dose at least 3 hours before bed, and I usually pop a 10mg melatonin and 100mg benadryl to help me fall asleep, still takes about an hour though. Plus I only really trip on Fridays/Saturdays and always give try to give myself a "Sober Sunday" to get back in the groove of things.
 
Rectal dosing is brilliant with the 2C-x. The come-up is really present, lacks the body-load of oral dosing, and produces a devastating peak. I think if nausea is a real problem that you can't tolerate, a light anti-emetic would be okay without impacting the nature of the trip too much. I do stagger my 2C-T-2 doses more often than not, for a bunch of reasons. It definitely eases you in to the trip more gently, but it depends how you like it. It allows you to gauge your dose better if you're dosing high, and it extends the trip. Forget snorting, it's purely unpleasant.
 
The first thing I will be getting if I get a proper chance is ondansetron. That sounds like a good way to combat 5HT-3 agonism induced nausea. And while some dissociatives may help with the body load by simply distorting your bodily feelings I would rather keep the trip 'clean'.

I have been a great fan of mixing stuff. But now I don't think it's such a good idea anymore.
 
Fresh ginger root is the best thing for nausea I have found. First couple times I did 2ce the nausea bothered me somewhat but not too bad. Although it can create a bad mood for the trip, that's the worst part of it. The ginger root completely killed any nausea I had. They have it at local supermarts extremely cheap. Cut it up into tiny pieces and chew on one if your stomach starts feeling weird.

The taste of it is very strong. Kinda feels it surrounds you while tripping. Makes me feel cozy.
 
I tried Ginger, made Ginger Ale with real ginger. It didnt work, maybe it wasnt gingery enough. I've also tried various OTC medicines includng Diphenhydramine but they didnt work either.
 
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