• Neuroscience & Pharmacology Discussion Welcome Guest
    Posting Rules Bluelight Rules
    Recent Journal Articles Chemistry Mega-Thread
    FREE Chemistry Databases! Self-Education Guide

  • N&PD Moderators: Skorpio

N,N-dimethyl-lysergamide.

Not not DMLSA. It's DAM-57. There is some contradictory information out there....some reports note mild LSD-like symptoms...others report absence of activity. I'm sure at some level there are effects, but the question still remains about signal to noise ratio.
 
Yeah and there was SoDAMN Insane ...

Seriously,maybe with the MET moiety you'll get into the ballpark,but Lysergolines are not my field.
 
No, but I don't have to take it to know.

Lysergamide is active.
N,N-dimethyl-lysergamide is more active.
N,N-diethyl-lysergamide is most active.
N,N-dipropyl-lysergamide is less active than^.
 
Last edited by a moderator:
Helios. said:
No, but I don't have to take it to know.

Lysergamine is active.
N,N-dimethyl-lysergamide is more active.
N,N-diethyl-lysergamide is most active.
N,N-dipropyl-lysergamide is less active than^.
Click to expand...

Actually the S,S 2,4 dimethylazetidine derivative is the most active.
and by inference the 6 ethyl and 6 allyl derivative even more so.
I am aware of the dimethylazetidine having been bioassyed and it indeed is most potent.

the s 2-butanamide is also about as potent as Lysergide. there are no reports of this having been taken by humans, however I doubt that there wasn't some accidental ingestion.

when it comes to ergolines David Nichols knows more than practically anyone,
http://www.heffter.org/review/Review2/chap6.pdf

lysergamine (8-NH2 ergolene) is inactive as a hallucinogen. but is active at dopaminergic sites and stimulates prolactin release, however lysergamide (8 CONH2) is robably only psychedelic at doses where the sedative effects are more prominent.
the effects of ipomoea and rivea and argyrea seeds are probably more to do with the ethanolamide.

over to helios..he knows
 
Helios. said:
No, but I don't have to take it to know.

Lysergamine is active.
N,N-dimethyl-lysergamide is more active.
N,N-diethyl-lysergamide is most active.
N,N-dipropyl-lysergamide is less active than^.
Click to expand...

Why did you start the thread then?
 
Helios. said:
No, but I don't have to take it to know.

Lysergamine is active.
N,N-dimethyl-lysergamide is more active.
N,N-diethyl-lysergamide is most active.
N,N-dipropyl-lysergamide is less active than^.
Click to expand...

Take a look at TiHKAL and PiHKAL. You'll find several analogues of very active compounds that are not active, even though shulgin was sure they'd be active from the structural similarity.

I can look up examples but I'm honestly too lazy to do so. Though I am sure you've come across some :).
 
^^^But you asked if DMLSA was active and then went on to say in a subsequent post that it was. I don't understand why you bothered to ask aquestion that you knew the answer to . . .

I am skeptical, I suspect some googlised regurgitation . . .
 
I dreamt last night that N,N-dimethyl-lysergamide (DAM-57) is stronger than
N,N-diethyl-lysergamide (LSD-025).

vektor,
which is correct?
 
I was actually intrigued about the whole taking lysergic acid Amide and reacting it with Aldehyde to turn it into Lysergic Acid HydroxyEthyl Amide.

I was just reminded with all of this talk of Ergolines. Its a shame that thread died out.

Ive had one good concrete psychedelic experience with Morning glory. All of my other experiences were just around threshold experiences, and I know that the ergolines in Morning Glory have so much potential.

Its just a shame that you cant get the good alkoloids out with out getting all of the nasty stuff too. The LSA just does not seem to do it, because ive done basic extractions, and they just dont get the job done.

By the way, what I said up there was "I dont know what" right? Its been so long since using french!:\
 
Helios. said:
I dreamt last night that N,N-dimethyl-lysergamide (DAM-57) is stronger than
N,N-diethyl-lysergamide (LSD-025).

vektor,
which is correct?
Click to expand...


But you have answered this several times already- I don't understand you dude.
 
You must log in or register to reply here.
Top