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Opioids N.b. methylphenidate/Concerta XL-will this help @~300mg dose with opioid withdrawals?

I_Stay_Dead

Bluelighter
Joined
Apr 15, 2008
Messages
301
Hello friends, fellow sufferers, fellow "high-ups."

If someone was going through a fentanyl & oxycodone withdrawal, from a fast taper, which has help him a bit nut not a great deal, can you help with good advice, after reading this, please? .... Well, this individual used a LOT of benzos last night to sleep. Took loperamide. Both helped but seemed to take an hour, felt like a month, to give some relief. This morning he's drinking rehydration drinks over and over. He took 288 mg of the slow-release methylphenidate, also-called Concerta XL, or the same stuff as Ritalin but Ritalin is IR [instant-release,] whereas the Concerta XL is slow release. I'm unsure whether this lasts for twelve-, or twenty-four-hours. Seems to last twelve-hours for main effects, the 'drop off' afterwards. This cold-turkey, well, with a fast taper to make it less intense, is still a cold-turkey. Rushing to the toilet frequently. Bedsheets, t-shirt, drenched in sweat so much so they stink of human sweat days-old. There was until quite a lot of benzoz and an antihistamine gen.-1 taken by him yesterday. Helped him sleep, together really did reduce withdrawals by 80-percent in his subjective experience. Now onto today. He's used all his benzos. Whatever happens, he takes the entire pack to get some sleep & blackout. His usual daily dose of methylphenidate is hmm 72 mg, this is not bothered with though when on opioids because the methylphenidate may be Schedule Two on their drug-prohabition, anti-human STATUTES, [not laws,] .... to get to the point, will this dose he has already taken, [yeah he should ask the take, not take then ask, "will this kill me, put me in a seizure, etc." He does have seizures. I went out a purchased a lot of loperamide for him. All he can do is lay on his soaked bed, rush to the toilet, make & drink his re-hydreation formula liquid. It's the electrolyte re-balancing liquid made by adding a sachet's powder to a glass then topping-up with water, then drink slowly but to get it all down within 30 mins. Strangely it doesn't come straight out either as vomit or ... elsewhere ;) .

The question is, having read above for the context, previous "tolerance" or use of methylphenidate, etc. Will this high dose, and the electrolyte re-balance drinks, one per hour or so, however dehydrated he feels. He takes 1st-gen. anti-histamines at the prescribed/pharmacy-purchased-so-dose-on-the-packet, doses. He takes these to prevent nausea and for all the affects anti-histamines have at medical doses, i.e. he's not "trip pin'" on diphenhydramine. So my main questions are;

Q. {Question-One:} given what he's been through & is doing - what best pharmacy-brought-w/o-script [O.T.C. - over-the-counter] - & which ones - would help the opioid withdrawal?
Q. {Question Two:} Will 288 mg of methylphenidate help? if so, then by how much?
Q. {Question Three of Three:} Is loperamide sublingual [expensive but with it if it's better] or the capsules or tablets better, in terms of kicking-in fastest, etc, any other reason(s.)? All come in packs of 6; you can buy 10 @-a-time due to their "GSL" legal status which is lower than over-the-counter - you can but them at a supermarket at a normal checkout. Will this stuff work?


Thanks, he;s home-bed-&-toilet-wridden. I want to help him. He already took the 288 mg of slow-release methylphenidate [Concerta XL] & he wants to know will the or the in combo with the others I can get for him since none require a prescription; will what he's taken help & will my suggestions help him? I've gone through cold-turkey so my experience taught me that I'd even help Adolf Hitler without a second's thought. I wouldn't wish cold-turkey from opioids on any one. He's coming off fentanyl matrix patches, it took years for him to reach his current tolerance, now though he takes a FULL 100 mg/h patch sublingually, twice-daily. {I'M NOT ONE TO GIVE OUT WARNINGS USUALLY. I'LL MAKE AN EXCEPTION HERE. AN IV HEROIN DAILY THREE OR FOUR OR FIVE BAG INJECTOR, SOMEONE WITH THAT SORTH OF TOLERANCE - ADDICTED PHYSICALLY, PSYCHOLOGICALLY, - MISS A BAG, FAMILIAR PHYSICAL WITHDRAWAL HITS - HORRIBLE IS A WORD THAT DOESN'T BRGIN TO EXPLAN OR DESCRIBE THAT EXPERIENCE. FOR THIS I.V. HEROIN USER, EVEN ONE-QUARTER OF A MATRIX 100-MICRO-GRAM-PER-HOUR PATCH UNDER HIS TONGUE, COULD EASILY - VERY EASILY - CAUSE AN O.D. REQUIRING AN AMBULANCE TO ARRIVE VERY QUICKLY AND ADMINISTER THE MU-OPIOID-RECEPTOR-ANTAGONIST, BY I.V. INJECTION, OR SUBLINGUAL GEL IF NO VEINS CAN BE FOUND/ACCESSED - SO PLENTY ON SUBLINGUAL ANTAGONIST GEL THEN AN I.V. INTO YOUR FEMORAL VEIN ONCE IN HOSPITAL AFTER OBSERVATIONS - THRY'LL TRY OTHER VEINS FIRST, BUT USE THE FEMORAL ONCE IT BECOMES CLEAR HIS VEINS ARE FUCKED ALL OVER. SO PLEASE BE AWARE - VERY FEW HUMAN BEINGS CAN USE AN ENTIRE 100 MCG/H PATCH TRICE-DAILY SUBLINGUAL - EVEN HEAVY, LONG-TERM USESRS OF I.V. OPIOIDS, PLEASE REALISE THAT THE [ROA] (WAY,) THE DOSES, ETC. OOF HIS SUBLINGUAL FENTANYL USE, NOT ONLY ARE RIGHT AT THE TOP REQUIRING VERY RARE, HUGE, ALMOST UNBELIEVABLE LEVELS OF TOLERANCE.} Just to finish taking about his fentanyl use. Cold-turkey is the worst I've EVER seen or ever experienced. There simply aren't words in my vocabulary which do justice to the motion-picture of hell you experience. Of all opioid cold-turkey withdrawals. From sublingual fentanyl at those doses, to nothing, well please get other opioid - go on MMT, - ANYTHING - , first, because I can't tell you how bad it is, honestly, you would have to experience it to understand. I feel that some things in life have to be experienced. Any description, hover well-weiten, simply cannot equate you with going through the experience.

With everything I've written in mind. Please can you give some SAFE, knowledgeable, answers to my friend, most of all - the fast we you can reply, the faster I'll know how to safely help him. Thank-you for reading. Thsnk-you in advance for any constructive replies. :)

MAIN QUESTIONS IN BOLD IF YOU DON'T HAVE OR CAN'T FIND TIME TO READ THE REST. ALL REPLIES ARE GREATLY APPRECIATED.
 
I'm not too knowledgeable on opioid withdrawal but i'd leave out the methylphenidate.. It may increase anxiety and lessen the chance of sleep..

Also, stimulant withdrawal isn't really harmful.. it includes feeling overly tired (and sleeping a alot) and hunger.. both could actually help this situation, as far as i know..

Valerian root, alcohol, loperamide, and anti-histamines such as diphenhydramine are all i can think of that could possible help withdrawals. (without being able to get a hold of some benzos)
 
^ I agree with leaving out the methylphenidate. On top of it keeping you from getting any sleep, it can cause more dehydration at a time when you really need to be staying hydrated since you are losing so much fluid.

As for the OTC meds, I suggest reading through this thread for answers about that and anything else having to do with opiate withdrawal. You seem to be on the right track with taking an antihistamine and loperamide. I have limited experience with the loperamide, and have only taken the 2mg tablets, so can't really recommend one way or the other when it comes to tablets or liquid formulation.
 
Diphenhydramine compounds the restless legs pretty badly in my experience, I'd avoid it if you can. Low-dose doxylamine + melatonin is the way to go.

Methylphenidate might do you some good, but if you're going to use stimulants during opiate withdrawal it's important to keep the dosages as low as you possibly can... if anything they should be used as a tool to assist you instead of as a drug to cure you. They can really jack up the anxiety and you're bound to become more dehydrated as Tommyboy mentioned, so make sure you're staying hydrated. Take them first thing in the morning and avoid re-dosing so you have a better shot at sleeping later that night.


With loperamide, I've always just stuck with the regular tablets. The liquid stuff didn't seem to work any faster, but I have only used the liquid loperamide that one time so I suppose I can't really say I gave it a fair shot. I've tried the liqui-gels and they actually seemed to make the cramping worse.
 
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