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Mushrooms then LSD three days later

The Dr

The Dr

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I dosed 4.5 grams of very good mushrooms two days ago. I've only tripped (real tripped) just one time and that was on this dose of mushrooms in the past 10 months. I've come across from very potent LSD that I want to try tomorrow, or maybe sometime this week. I will say that after the mushroom trip I have had no delusional thoughts nor did I create any falsehoods within my trip, meaning it was a very healthy clean trip a +++.

Think if I kept my frame of mind and took these suckers I'd be doing any harm? I know you should space this out but I'm not a eraserhead. I had been one in the past but that was prior to those 10 months of being clean off of hard psychedelics. My brain is clean and ready to go.. feel like I'm answering my own questions, but SHOOT! %)
 
You wouldn't do any harm but you might have some tolerance.
I'd wait a week, a 4.5 gram mushroom trip should leave you with a very noticeable tolerance
 
There's no cross tolerance between mushrooms and LSD. I know from my eraserhead days
 
However, thanks for the answer. I wasn't sure about the neurotoxicity of it. Cool beans! There really isn't a rush, I haven't done LSD in 10 months or so and I came across it today. Thanks for the replies!
 
There is cross tolerance between LSD and Mushrooms in my experience... you need to leave it a week to get full effects... I once took 1000mics 3 days after a 5gr mushroom trip and only really got color saturation... severe cross tolerance.
 
Disagree 100%.. maybe different brains? I know I'm gonna go nuts on this.. I've made my mind up, I'll do a trip report of the mushroom trip and this one and report any differences. I'll have pen and paper and make it to the dot on visuals/ time it takes/ everything.
 
Just found some information on this topic.

"In two experiments, using a cross-over design, the development of directrd tolerance to LSD and psilocybin was measured after 10 (Experiment I) or 9 (Experiment II) volunteers had taken LSD in doses increasing to 1.5 meg/kg over the course of 6–7 days (Experiment I) or 13 days (Experiment II). On another occasion, the same patients received psilocybin in doses increasing to 150 mcg/kg over the course of 6–7 days (Experiment I) or 210 mcg/kg over the course of 13 days (Experiment II).
The development of cross tolerance to psilocybin in patients directly tolerant to LSD was measured by challenging the patients, after they had received LSD chronically, with 150 mcg/kg (Experiment I) or 210 mcg/kg (Experiment II) of psilocybin. Cross tolerance to LSD was evaluated by challenging the patients, after they had received psilocybin chronically, with 1.5 meg/kg of LSD.
A high degree of direct tolerance to LSD developed in both experiments, as manifested by statistically significant reductions in six of the seven parameters of response. Patients directly tolerant to LSD were also cross tolerant to psilocybin on five (Experiment I) or four (Experiment II) parameters.
Definite direct tolerance also developed after chronic administration of psilocybin in both experiments, but statistically significant reductions occurred in fewer parameters of response (four in Experiment I and three in Experiment II) than was the case with LSD. Patients chronically treated with psilocybin were also cross tolerant to LSD on four (Experiment I) or three (Experiment II) measurements. The degree of direct tolerance to psilocybin was less than the degree of direct tolerance to LSD.
The development of cross tolerance between LSD and psilocybin reinforces the idea that these two drugs cause psychic disturbances by acting on some common mechanism, or on mechanisms acting through a common final pathway.

What this particular study is basically trying to say, is that psilocybin seems to cause a lower degree of tolerance than LSD.

In other words, taking LSD after LSD or mushrooms after LSD may possibly produce a greater (cross) tolerance than taking mushrooms after mushrooms or LSD after mushrooms.

From experience, I would have a tendency to agree with this theory. "

Also these people had this shit going into them at a constant rate over a week.
 
well LSD trips are more inconsistent for me in general than shrooms but I do need to say I'm 100% sure of this for me personally, there are cross tolerance effects, not complete cross tolerance, and this isn't just from one experience, maybe 50? and friends would concur I bet, but hey if you're not experiencing cross tolerance, fantastic, then enjoy your trip even more.
 
I just read your experiment post... I have to remark I was replying to your comment "There's no cross tolerance between mushrooms and LSD." -- these experiments would definitely seem to indicate otherwise, correct? or am I misunderstanding something completely?
 
Yeah that's what I'm trying to do. Get that correct mindset, and this will be interesting. Also to add the dosage's you listed are about the same of what I'm doing tonight with the exact amount of time in between. I'll send you a PM with my results just for shits
 
lbeing789 said:
There is cross tolerance between LSD and Mushrooms in my experience... you need to leave it a week to get full effects... I once took 1000mics 3 days after a 5gr mushroom trip and only really got color saturation... severe cross tolerance.
Click to expand...

That's what I'm referring too.
 
I wanna also say I ended up taking 1000 mics, because I needed to, to get to where I wanted to be, due to what I considered tolerance from the mushrooms, I didn't take it all at once, I split that into 3 over maybe 5 hrs..., ya know, taking 300 (or 3 100mic blotters), then 3 more when I got barely anything, then 4 more again, then I got some effects, but surprisingly weak... but anything could've happened in this case, LSD is more inconsistent and who knows, maybe the substance deteriorated, I think you're going to have a good night anyway.
 
The Dr said:
That's what I'm referring too.
Click to expand...

Well 1000 mics for me and barely any effect is something I would consider severe... I don't really want to keep on discussing this, you said no tolerance, I said severe tolerance, the study you quoted says somewhere in the middle, you can see where we're at with this argument ;)
 
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