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Most surprising drug information

The amount of ignorance about drugs which many people of the society have, and share with others in some attempt to 'educate' on the evils of drugs, is really quite appalling. I've always found the magnitude of society's deep ignorance and misunderstanding about drugs, in all dimensions, to be shocking; even being aware of it for many years, now, it still shocks me - I don't get it. But, that does not really answer the question about drugs themselves.

I suppose I was a bit taken back when I actually used heroin (twice), not being at all opiate-naïve, but being quite surprised about how I felt about it versus how others regard heroin and its use; for me, it was another opiate, about as enjoyable any other opiate (e.g. codeine, morphine, oxycodone, hydrocodone, hydromorphone, buprenorphine, and others). Relative to other opiates, it did not bear any particularly addictive allure nor did it produce any particularly profound euphoria - as I said, it was just another opiate. I didn't feel ashamed or dirty using it or after using it, at all, knowing well that I was safe about my drug use. It didn't make me any more of a dope-fiend or addict than I already was. Now, I do LOVE opiates, but if I were offered a month's supply of heroin or a month's supply of oxycodone or a month's supply of hydrocodone, I really wouldn't be disappointed with whatever I got (so long as I got a month's supply I was offered).

In the same vein, something that did really surprise me back when I was just beginning to actually use drugs, was the truly wondrous euphoria specific to opiates and just how powerful that euphoria was. Nothing is more comforting, more absolutely and utterly assuring and warming, more cozy and coddling, than an opiate, EXCEPT for the true love of another, IME. Before I actually touched an opiate, I knew for a while, more and more consciously, that I would end up falling in love with drugs, and, in fact, opiates, specifically, but to have that verified via my own experiences was incredible. They exceeded the greatest expectations I ever had for any drug. Maybe not exactly the type of answer asked for, but the truth.
 
finding out that something like krokodil exists / people actually inject that :(
Yeah, that makes my heart hurt for them.

I was surprised to find out Cannabis is being used to (successfully) fight some cancers.

I find it insane (though not surprising) that we still have a ridiculous drug prohibition.

I was shocked to learn that Benzos are the most addictive class of narcotics.

I was shocked to learn people enjoy DXM or Salvia.
 
That I didn't like heroin.

After the media raging on about how you can get addicted after just one time. When it finally came to it, I was waiting for something amazing and it was a massive let down. I did it a few times just to make sure but I just don't like it. In my head it was like the mecca of drugs and I have super addictive personality. But nada.
 
How stupidly the DEA chooses to schedule drugs. So marijuana and psychedelics have NO medical use and high risk of physical and psychological dependance huh? So your trying to tell me benzos like xanax which an actually kill when quit abruptly, which are schedule IV, have A low abuse potential (clearly says "low abuse potential on their site"). Lmfao the DEA is fucking retarted.
 
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The fact that our prescription drugs are benzos, amphetamines, opiates etc. but anything thats not an rx drug, even fuckin bud, is looked down upon.
 
A recent study indicates that 6-apb lacks activity at SERT. Whaaaaaa?

ebola

Wow. I've never tried it personally, but what the fuck? From what I gather it's best compared to mdma if ur gonna compare it to something.

Got a link for that? I'd be interested to read it.
 
Here ya go: http://www.sciencedirect.com/science/article/pii/S0014299912010114

It could be that strong 5ht2b agonism confers lots of 5ht release on its own, sufficient for entactogenesis. But I want to see replication. They also found mephedrone to lack strong affinity for SERT, in conflict with at least 1 prior study...but results for most of their other 'control compounds' seem plausible.

ebola
 
Nothing really.. Even as a kid in middle school where they made me go through a "DARE" anti drug campaign, which involved doing silly dances about how you're above the influence of drugs, I always knew all the propaganda was full of shit.

Although I must admit learning the fact that tobacco/alcohol kills orders of magnitude more people than all the other drugs combined was surprising to learn. That really sealed the deal for me in terms of realizing the war on drugs is BS.
 
Here ya go: http://www.sciencedirect.com/science/article/pii/S0014299912010114

It could be that strong 5ht2b agonism confers lots of 5ht release on its own, sufficient for entactogenesis. But I want to see replication. They also found mephedrone to lack strong affinity for SERT, in conflict with at least 1 prior study...but results for most of their other 'control compounds' seem plausible.

ebola

Cool, thanks man. I'll check it out right after I've taken my nap.
 
The fact that our prescription drugs are benzos, amphetamines, opiates etc. but anything thats not an rx drug, even fuckin bud, is looked down upon.
Marijuana is basically the only drug that isn't prescribed in a true pharmacy in the U.S. It's only half legal in a 14-15 states. And you are so right. I can think of several opiate painkillers stronger than heroin, we have all different types of Amphetamine Salts in pills--including meth-amphetamine in a pill, there's z-drugs, benzos... Almost anything you could buy on the street is available from a pharmacy. I recently heard a report on NPR stating that they are experimenting with treating chronic depression patients that don't respond to SSRIs with I believe bi-weekly injections of Ketamine, with great success. And that PTSD sufferers have seen success with MDMA. All drugs have value.

ensta:, "That I didn't like heroin" -- does not surprise me at all, opiates are an acquired taste. Especially if you skipped the vicodin/perc to OC/Fent stage of the game.

That Amazonian tree frogs have so many different weaponized psychoactives.
 
Name one drug that is.

Good point, I couldn't. Just found it surprising considering how loved MDMA seems to be. Granted, its supporters and advocates are incredibly vocal, but for all the bad stuff said about it, there'll be 1000x more reports to the contrary. You'd think it was God's pee, the way people talk about ecstasy. This isn't a new realization anyway, I found out very early on with my experimenting that the only truth is one's own.
 
That everything I'd ever heard about drugs was a lie, illegal ones weren't dangerous with the right knowledge, and people over exaggerate everything about them

That a heroin is basically the same as legal, prescribed, medications aka opioids.

That if not mixed or IV'd , opiates and benzos are actually not that easy to overdose on. (If you take basic precautions and have basic knowledge)

Acid and mushrooms don't make you see elephants and gnomes, or think you can fly
 
^
Thats quite interesting.
What do they add to tobacco MAOI-wise? I know that impact chemistry is meant to deliver the nicotine to the brain quicker but I thought that nicotine itself was an MAOI?

Edit: scratch that, I looked it up and see that tobacco contains norharman and harman (beta-carbolines).
These exist naturally in tobacco though. I dont think their 'added in'.
The lack of these MAOIs in nicotine replacement treatment is likely why it doesnt have the same kick.
However, this is also why nicotine replacement treatments are effective for quitting smoking. They fill the nicotinic receptors but lack the addictive kick of tobacco smoking.
Like subs for ORT.lol
 
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Hey no stress mate, I had the wrong end of the stick at first aswell.lol
Plus, tbh your originalpoint was right. Obviously there is a real difference in the effect between tobacco and NRT.
 
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