Alcohol and opiates together just do not get along.
Now you had a beer. If it had been a few shots of liquor with the M, well as I understand, with opiates running in the system (maybe in particular real opiates, vs. Synthetic opioids?) ethanol becomes methanol. I dont think many combine these, at last in noticeably harmful amounts. I never did much, due to digestive system upheival, and just being two things would rather keep apart to enjoy on their own, saving something for later basically. Not good for respitorary health (e.g. deaths on "sizzurp ") and might just make a person's liver crawl right out of their body, in order to get away from it.