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Opioids Morphine IR questions

T

ThePurpleMan

Greenlighter
Joined
Jul 13, 2026
Messages
20
Hey, so I would like to try Morphine IR for recreational purposes. I got a few 10 mg pills from a friend.
I just want to be safe, instead of just yolo it and hoping for the best, so how can I be safe trying this?
What dose should I start with as a guy at 34, at 131 kg? (Don't know if that's needed to say, but ya know)
 
Depends on tolerance. Try 30mg's first cause it may make you puke. Just does it to some people
 
ThePurpleMan said:
Tried 10mgs a few times, it did give a little relaxing feeling.
So I guess I dont really got a tolerance, so still 30mg or lower would you say?
Click to expand...

30 should be good but be aware some people do puke alot from morphine. It's always a possibility if you arent used to it
 
Isn't morphine quite well known for it's low oral bioavailability? About 24-26% in most people.

Now I'm not about to suggest someone consume a non-prescribed medication much less suggest parentheral ROA but I've always thought morphine pills must be extremely attractive to users who do employ paretheral routes. I mean, if prescribed, even a urine, blood or skin test will just demonstrate the presence of morphine.

That said, poppy seed bread can also produce a false positive so in essence, it's one of the few opioids where 'plausable deniability' is acceptable (at least in most nations).

Does nothing for me whatsoever but that the thing with ANY psychoactive - YMMV.
 
paranoid android said:
30 should be good but be aware some people do puke alot from morphine. It's always a possibility if you arent used to it
Click to expand...
Okay, so currently on 20 mg to make sure I'm doing good on that dose, and I don't really feel anything insane- a little relaxed, but no nodding or like euphoria at all, which is sad -_-
The package my friend gave me said that it expires 07/2026, so that's this month, aka, it's expired tomorrow, but then again, how much of the morphine really doesnt work after maybe a month or so of it being expired, and can it really be because it's expired that I don't feel this amazing feeling people always say they feel on opioids?

(Note: I am prescribed 10 mg twice a day on as-needed, and it's been 5 days since my dose of 1x10mg, so tolerance shouldn't be fucked right?)
I am prescribed Morphine IR myself, but since I just got that script for the first time this month, I want to show that I actually don't abuse it (It's for real back pain, believe me or not), so I'm thinking, would I feel any stronger effect if I took 20 mg of that package that isn't expired?
 
Yea we are taking the morphine orally correct? 4dqsar's #'s are indeed correct and you should treat the conversion chart as such *unless there is an ROA column or w/e*

tolerance is not your problem.

I had a snorted morphine habit for many years and the bioavailability sucks on that as well but I FELT it worked a little better -- I believe statistically it is even worse bioavailability, I ran the experiment enough times to know it worked better for me.

Honestly I would try eating 30mg waiting about an hour or two and than snort another 30 IF NECESSARY. Of course try lower doses first and KNOW YOUR TOLERANCE.

(Always have narcan and someone with you who knows how to use it-- there is my out)
 
ThePurpleMan said:
Okay, so currently on 20 mg to make sure I'm doing good on that dose, and I don't really feel anything insane- a little relaxed, but no nodding or like euphoria at all, which is sad -_-
The package my friend gave me said that it expires 07/2026, so that's this month, aka, it's expired tomorrow, but then again, how much of the morphine really doesnt work after maybe a month or so of it being expired, and can it really be because it's expired that I don't feel this amazing feeling people always say they feel on opioids?

(Note: I am prescribed 10 mg twice a day on as-needed, and it's been 5 days since my dose of 1x10mg, so tolerance shouldn't be fucked right?)
I am prescribed Morphine IR myself, but since I just got that script for the first time this month, I want to show that I actually don't abuse it (It's for real back pain, believe me or not), so I'm thinking, would I feel any stronger effect if I took 20 mg of that package that isn't expired?
Click to expand...

Try 40mg's next time or boof it if your ok with that. That works better
 
^Valid if you are willing to boof it I think it jumps up to around 60% ish?? Or is it higher -- Still DOUBLE ORAL and no 'does it work' of snorting.

So bend over and take it like a man
 
paranoid android said:
Try 40mg's next time or boof it if your ok with that. That works better
Click to expand...

HALVE the dose if swapping from oral to parentheral administration.

You can always take a bit more, you can't discover it's too much and magically take a bit less.
 
notsmokeymcpot42088 said:
^Valid if you are willing to boof it I think it jumps up to around 60% ish?? Or is it higher -- Still DOUBLE ORAL and no 'does it work' of snorting.

So bend over and take it like a man
Click to expand...
All I have to say to taking it from behind :ROFLMAO:
Wtf Cat GIF
 
notsmokeymcpot42088 said:
Yea we are taking the morphine orally correct? 4dqsar's #'s are indeed correct and you should treat the conversion chart as such *unless there is an ROA column or w/e*

tolerance is not your problem.

I had a snorted morphine habit for many years and the bioavailability sucks on that as well but I FELT it worked a little better -- I believe statistically it is even worse bioavailability, I ran the experiment enough times to know it worked better for me.

Honestly I would try eating 30mg waiting about an hour or two and than snort another 30 IF NECESSARY. Of course try lower doses first and KNOW YOUR TOLERANCE.

(Always have narcan and someone with you who knows how to use it-- there is my out)
Click to expand...
Does snorting it even help on the bioavailability of it?

I am just kind of surprised by it, the first time I tried the 10mg I was pretty high, but since then, haven't been able to hit that kind of high again
 
Empirically - No I believe is the answer. I think it goes down to like 15% ish

in practice IME and most people who I have known that used morphine -- Yes you get more of a buzz.

I would think anything that isnt absorbed by your nasal is eventually swallowed anyways but it is really kind of a toss up. You wanna be sure ya gotta toss yourself or get pokey
 
paranoid android said:
Try 40mg's next time or boof it if your ok with that. That works better
Click to expand...
On 40 mg right now, and still the same, no euphoria or anything, not even a bit more relaxed, just feeling a bit as if I gotta puke, but it's more in the background, like it was on the 20mg.
Imma take a break after this, maybe until next weekend, to reset my tolerance a bit.

Could it really be because the pills expired yesterday? I mean, like, I guess the drug gets less and less strong from the first day they were pressed.
So if they are now "expired", would that maybe make them worse, or maybe that could be the reason I am on 40mg as naive to opioids and not really feeling them?
Already at the heavy dose based on https://psychonautwiki.org/wiki/Morphine
 
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if you feel like your gunna puke you are high. Any itchiness or nodding off and such? Compared to say alcohol it is a pretty chill high for the price you pay

Snorted or Oral or you boof it? 60mgs is what I want to recommend for people to dose oral or snorted but some ppl metabolize shit really well and it could be a death sentence for them....believe they in the minority though
 
notsmokeymcpot42088 said:
if you feel like your gunna puke you are high. Any itchiness or nodding off and such? Compared to say alcohol it is a pretty chill high for the price you pay

Snorted or Oral or you boof it?
Click to expand...
Oral, and no itchiness or nodding at all; that's why I am confused. I even chatted with a few friends like no problem, as when I am sober, and right now I'm not even tired/sedated at all.
I am sitting here programming while on 40mg of morphine; I normally am on like 2 beers, not able to write a simple message, so I would assume Morphine would do more than 2 beers normally do.

I just did an edit of my old message, so here is the stuff I added:
Could it really be because the pills expired yesterday? I mean, like, I guess the drug gets less and less strong from the first day they were pressed.
So if they are now "expired", would that maybe make them worse, or maybe that could be the reason I am on 40mg as naive to opioids and not really feeling them?
Already at the heavy dose based on https://psychonautwiki.org/wiki/Morphine
 
ThePurpleMan said:
Does snorting it even help on the bioavailability of it?
Click to expand...

Well, with appropriate formulation it would seem to be around 60%. I think even if a person just snorts a crushed pill, the fraction not absorbed through the mucus membranes of the nose still increases mucus production so that which is not absorbed through the nose still ends up being absorbed by the stomach. Hence snorted, the total bioavailabiliy will increase.


I think it also important to note that plasma levels may demonstrate a delay i.e. if it's just dissolved in mucus and stays in the nose, quite a lot of it might be absorbed but not instantly. So it could be that if researchers took blood samples right away, thay may be understating the total bioavailabiity.

I only know of one person who went to the trouble of isolating almost pure morphine but they claimed it was quite close to morphine delivered via slow infusion i.e. it took a few minutes to really do much and upto 10 or even 15 minutes until it felt 'strongest'. Obviously 'strongest' is a totally subjective description but this person was a post-graduate student and in retrospect I think took a very keen interest in finding ROAs which yielded the highest total bioavailability.

I'm just thankful that their phobia of needles was as profound as my own.
 
4DQSAR said:
Well, with appropriate formulation it would seem to be around 60%. I think even if a person just snorts a crushed pill, the fraction not absorbed through the mucus membranes of the nose still increases mucus production so that which is not absorbed through the nose still ends up being absorbed by the stomach. Hence snorted, the total bioavailabiliy will increase.


I think it also important to note that plasma levels may demonstrate a delay i.e. if it's just dissolved in mucus and stays in the nose, quite a lot of it might be absorbed but not instantly. So it could be that if researchers took blood samples right away, thay may be understating the total bioavailabiity.

I only know of one person who went to the trouble of isolating almost pure morphine but they claimed it was quite close to morphine delivered via slow infusion i.e. it took a few minutes to really do much and upto 10 or even 15 minutes until it felt 'strongest'. Obviously 'strongest' is a totally subjective description but this person was a post-graduate student and in retrospect I think took a very keen interest in finding ROAs which yielded the highest total bioavailability.

I'm just thankful that their phobia of needles was as profound as my own.
Click to expand...
Thank you for that info.
Yeah, I got a big fat phobia of needles too, so just the thought of having to poke myself is crazy, and one of the things I have always said I would never do no matter what.
 
@4DQSAR @notsmokeymcpot42088
Bois, I tried today with the newer package that wasn't expired, and since I haven't touched morphine since my last message, I decided to play it safe, so I took only 20mg of it.
I again didn't really feel anything, besides a little nausea, but when I remembered you (@notsmokeymcpot42088 ) telling me to try and snort some, I took a half 10mg, crushed it up, and snorted that (These 5mg was from the expired package)
What supprised me wasnt that I really felt I got any more of a "hit" out of it, but for some reason, my nausea went away pretty fast after me snorting 5mg of it, which is pretty odd, but again, I also do feel maybe a bit more happy, but dont know if thats really from morphine or just because I got over the fear of snorting Morphine.
 
Try snorting 30mgs than another 30 in about an hour -- hour and a half if you wanna be safe.

oral morphine is garbage and snorted works better for most people IME --- worst that happens is it ends up going down your throat and you end up getting it orally?

Take a benadryl with the second 30 mgs -- that was always part of my ritual.

Check out some trip reports on morphine, most ppl dont feel a good buzz till up near 60-100 mg's oral.......I remember being able to feel snorting a 30 though so I would start there. Should be roughly equivalent to 10mg's IV which is a common dose for
intolerant users.

you do not NEED a needle to experience a morphine high, a morphine rush, sure ... it is just a matter of finding the right amount. It is a more subtle buzz than say alcohol or mushrooms -- if you smoke pot definitely smoke some pot with it. Even when I was dependent I would not use unless I had some weed.
 
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