sounds like a dumb idea, at least the way you've structured it. Mushrooms is pretty much psilacetin and mdma and mushrooms is a good time(hippy flip). 4-aco-dmt and mdma would be a fine combo imo if you have taken both individually before, although you never know with new chemicals. I would take 100mg mdma and 15-20mg 4-aco-dmt. But i would just take mushrooms and mdma for a safer time. I don't know what "onetwo" means by saying 4-aco-dmt having a bad come down, in my experience I had a great feeling comedown, one of extreme joy and content with myself. Even the next day I felt good, MDMA on the other hand its a different story.