Mirtazepine and baclofen safe mix?

[bunge]

Would it safe for me to mix 5-10mg of baclofen with 45mg? Its to help me relax at night when not taking zopiclone as im reducing and im doing one night on and one off. I can leave an hour or two between dosing the baclofen and mirtazepine. ive been taking the mirtazepine for a couple of months at this dose and nearly six months in total so fairly tolerant. Please help. Thanks.

 

[Swimmingdancer]

Drug interaction checker just says the same warning they put on any CNS depressant drugs, so it's not very helpful. 5-10 mg of baclofen is not a high dose, that's a normal starting dose. 45mg of mirtazepine is considered a high dose, but if you've been on it for months I would assume that taking 5-10mg of baclofen should be pretty safe. Asking your doctor would be best though - were you not prescribed this?

 

[laCster]

you will be fine, jst dont go overboard. this combo will make you drowsy and you should not drive for sure!!

 

[bunge]

Ive stabilised on 45mg of mirtazepine for about two/three months. Ive not been prescribed baclofen but I have tried it before at 5mg. I am prescribed zopiclone 7.5mg and take that at the same time as the mirtazepine but was hopeing the baclofen wouldnt be anymore depressing to my cns then my current zopiclone/mirtazepine mix. Im aware that theres a heavy sedation aspect involved, just wanted to determine if it would make me ill or put me in any massive danger.