Mild adverse effects from 8.6 mg 4-HO-DiPT.HCl

[Thomas Davie]

I was looking for a tryptamine with (supposedly) little to zero body load, short duration of effects and approximate equivalency to mushrooms. I settled on the 4-HO-DiPT.HCl

Quick background; I'm 52, have well managed hypertension and kidney failure (which is kept in check as long as the blood pressure is). I've tripped about 60-70 times on mushrooms in the last 14 months. I get mild GI distress (some bloating, mild stomach pains and foul gas) from the shrooms. These symptoms seem to increase a bit when I switch strains or if I had a tolerance break of more than 7 days. At the time of trying this compound, I was on a 33 day break (I ate all my shrooms and was too lazy to start another flush).

I dissolved 8.6 mg in 2 ml distilled, deionized water and vortexed slightly. It easily went into solution. Stored in a 2.5 ml microcentrifuge tube, wrapped in parafilm and stored in fridge for ~3 weeks. I prepared several such solutions (~ 8, 10, 12 14 and 16 mg). No problem with solubility for all. The actual compound was weighed on a sub milligram balance.

On the day of trying this, I had no solid breakfast (2 cups of coffee and some OJ), a diet coke for lunch and 2 pieces of lasagna and 2 pieces of quiche for supper.

Substance was consumed ~3.5 hours after eating. About 4 beer on board. I'm aware that this is a sub active dose for most people. No testing for allergic reaction or working my way up from sub mg doses (although I have the capability to do so). The 2 ml of water was added to ice cold OJ. Taste was pleasantly bitter (rather like Alprazolam, which I chew for the taste).

No positive (psychedelic) effects were noted at all, and I wasn't expecting them. After 15 minutes I started to get leg tremors that persisted for about 8 hours. I would call them mild; they didn't prevent me from moving or going to the bathroom. About the 1 hour mark, I started to get diarrhea. I would call this moderate. 41 hours later I still have somewhat loose stools and excessive gas. Appetite was not affected and I have been using electrolyte replacements for about 24 hours.

Was lethargic well into the day after.

Thomas

(mods, I don't consider this a trip report, but if you think it is, please delete it and I will repost in the trip report section. I consider this to be acute non CNS effects).

 

[sekio]

This is pretty common with HO-DIPT. Some people just get terrible gastric issues.

 

[zn13bt]

I always got a ton of muscle tension when I used to do 4-HO-DiPT, sometimes to the point where it might look like I was having a seizure or something to an outside observer (I didn't ever lose consciousness though). Generally people report 4-HO-MET as having the least amount of bodyload among all of the tryptamines available on the market, that might be more along the lines of what you're looking for.

 

[Solipsis]

I am aware of 5-MeO-DiPT having significant potential for gastic issues, but I never heard of 4-HO-DiPT causing those problems. You sure you're not getting those mixed up, Sekio? Not that it would be impossible from my perspective, that is definitely not it - but I wouldn't call it typical from what I remember reading.

Personally I find 4-HO-MET to have a greater body load than 4-HO-DiPT (which is one of if not the lightest for me), but the body load of 4-HO-MET is virtually all pleasurable even at a dose of around 40 mg. I tried 4-HO-DMT last friday and found it to be significantly different from 4-HO-MET by the way.

In any case, YMMV: you can try to follow the trend / consensus about certain potentials or qualities of compounds but in enough cases people react differently and have opposite preferences. In such cases you just need to try a few other options until you discover your likes and dislikes with nuance.

 

[sekio]

I am aware of 5-MeO-DiPT having significant potential for gastic issues, but I never heard of 4-HO-DiPT causing those problems. You sure you're not getting those mixed up, Sekio?

I may well be. It's 5-MeO-DIPT "foxy methoxy" that has the reported gastric issues.

 

[Bone14]

I've experienced some gastric issues and stomach discomfort on 4-HO-DiPT, though never as bad as you describe there. Is gone the next day, and I've taking doses up to 80mgs.

 

[Thomas Davie]

I've experienced some gastric issues and stomach discomfort on 4-HO-DiPT, though never as bad as you describe there. Is gone the next day, and I've taking doses up to 80mgs.

The gastric issues are now resolved (thank god, because it's a work week). I think that largely any issues I encountered were due to my tolerance break from mushrooms. When I had started at the beginning of my 14 months of usage, the pain was intolerable; felt a bit like twirling razor blades in my stomach. The 4-HO-DiPT was nowhere near as bad.

Tom

 

[THCified]

I don't think it's the best idea to make solutions and store them for weeks on end... I'd make one shortly before ingestion, perhaps giving it a bit of time to fully saturate the solvent, but no more than ~1hr.

 

[Thomas Davie]

I don't think it's the best idea to make solutions and store them for weeks on end... I'd make one shortly before ingestion, perhaps giving it a bit of time to fully saturate the solvent, but no more than ~1hr.

Point noted.

A lot of the solutions (standards, reagents, buffers) I use at work are stable for significant periods of time, depending on the pH, temperature of storage and whether or not they are light sensitive (or oxidatively unstable). The 4-HO-Dipt was removed from the dark, solution prepared, and then stored away from O2, light and in the fridhe as soon as possible.

I was a bit hesitant to use this solution, but at the time I took it I did not have access to a balance or pipette....and I refused to eyeball.

Probably the best thing to do is preweigh specific amounts into volume calibrated tubes and then I can add liquid to the calibration mark without need of a pipette. And then my solutions will be as good as I can get.

Thanks for the heads up.

Thomas

 

[THCified]

Probably the best thing to do is preweigh specific amounts into volume calibrated tubes and then I can add liquid to the calibration mark without need of a pipette. And then my solutions will be as good as I can get.

Thanks for the heads up.

Thomas

You're welcome!

I think what you suggested is the best thing you can do, when you don't have permanent access to an accurate scale.

I just have one experience with 4-HO-DiPT to date, which was somewhat taxing but overall very cool, and i also had some residual after-effects for some days afterwards. As far as i remember somewhere between 3-4 days at most. But tbh, it was more or less pleasant and, of course, interesting.

What i experienced where some slight tremors and out-of-ordinary "muscle movements", the thing i liked the most was a very noticeable increase in sex drive/horniness, especially after ingesting some THC - but that subsided very soon after the actual experience.

If i read correctly between the lines of your initial post, you're interested in alternatives to shrooms, right? Even tho i don't really like to recommend ingesting something, there are some other, extraordinary enjoyable snythetic tryptamines besides 4-HO-DiPT. I've found 4-HO-DPT and 4-HO-MiPT to be really unique, interesting compounds, but 4-AcO-DMT simply is THE BOMB ! For more information try out the corresponding threads.