I've tried 180mg orally exactly once, it was WAY TOO MUCH. I actually vomited I was rolling so hard, my eyes were going crazy and I felt like I was going to pass out. Plus the comedown was pretty uncomfortable, with a lot of dysphoria. Never again.
I'm generally a very upbeat person (with no chemicals). Everybody I've given lowish doses to (75-100mg) has said its a very enjoyable experience, not overpowering, but euphoric nonetheless. I usually take 35-45mg with them and I am at the same place they are.
I must be sensitive to it, although I am not sensitive to MDMA, MDA, cocaine, methamphetamine, or amphetamine.
Like Ximot pointed out, you will be a very special person at a bar if you are on M1. Last time a lady attached herself to me and wouldn't let go of me. %)