While MDAI is supposed to be not neurotoxic, it still has an effect on your seratonin system. The reason why MDAI is not considered neurotoxic is that it only releases seratonin and not dopamine. The release of both of these neurotransmitters is why causes toxicity when taking substances such as MDMA. However, it still releases a lot of seratonin. So you will still need time for your brain to replenish it's supply of seratonin. As sekio said, taking a 4 week break would be best, but you can still have a good time if you wait 2-3 weeks.