Got to echo those comments about Methiopropamine potentiating MXE. It's a quite pronounced effect - and potentially dangerous!
I had about 50mg O-Desmethyltramadol, plugged, at about 4pm, then at 7pm had about 30mg MPA. Had another 30mg MPA at about 10:30pm and maybe 20mg MXE about 11pm, and went to the pub with gf and her new flatmate (my gf was moving in this weekend). By midnight the MXE had taken effect and it was noticeably stronger than if I'd just taken the MXE, my verbal skills were not great meaning I had to concentrate to order at the bar, but I managed, and I gradually straightened up a bit. Went back to my gf's flat around 1am, feeling fine and in control. Had some more MPA and a bit later, another maybe 20mg of MXE and perhaps the same of O-DT (hard to tell, we had no scales, just known, fairly small, quantities so I could divvy them into doses.)
Over the following two hours I gradually lost the ability to partake in conversation, when I did speak it was nonsense, and then I blacked out. This has never happened to me on MXE before, even on doses over 100mg. My gf told me I was in the toilet for ages so she came looking for me and found me trying to have a piss against the wall in the bathroom. Fortunately she prevented this, it wouldn't have gone down well with her new flatmate!
My gf put me to bed, and I got back up, stumbling into the kitchen and muttering nonsense - four times this happened before I eventually stayed in bed. I have no memory of this at all.
Nothing bad happened, and no-one was hurt, but it could so easily have gone bad. I dread to think what would have happened if I'd managed to get out into the street unbeknownst to the gf and her pal.
I suppose the booze or even the O-DT might have played a role in this too, but I didn't have much booze and I've combined booze, O-DT and MXE before without anything like this happening.
