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[Methoxetamine Subthread] Combinations

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I started my evening by taking 20mg of mxe, around 5pm.

After doing some stuff i dosed 1hit of dalai lama lsd around 8:30 pm, this was a nice amount which had me at a stable +++ while doing hits of m20 and mixing psytrance at home.

Around 00:00 i took a capsule of 30mg mxe and a few big hits of high grade indica weed, i have no tolerance to cannabis right now since i smoke about 1-2 joints per week at most nowadays.


Anyway this turned out to be a very strong ++++ with moments of total egoloss and confusion, scary at times since i did not expect to get this fucked up.

Very interesting visuals with me seing time moving before it did and other paranormal phenomena.

Also when i was going to bed i had a very hard time moving around when turning the lights off in my livingroom.

I was standing up and falling into a heavy hole when it got dark, had to really focus not to fall down and collapse.

Once in bed it was under control but very enlighting and healing, almost like a heavy aya sesion but different of course.


I do mxe every weekend so 30mg is usually nothing for me, so be careful when this dosing on lsd.
 
Is it SAFE for me to take MXE while im on Quetiapine (seroquel) ?? pleas HELP!!

Will I get the desired effects?, is it safe? ive been on it for just a bit less than 3 weeks its 25mg
 
I'm going to move this to Psychedelic Drugs since it involves interactions between MXE and another drug, you should get some responses over there.

BDD --> PD
 
I combined 130mg MXE with 400mg DPH.

What was remarkable was that my heart felt fine. A little weak, but I did not experience torturous, sharp pains like I would when I'd dose 400mg DPH without the MXE. But to make up for that, the headspace created was absolutely horrible. The DPH delirium should not be experienced together with MXE lucidity. I merged with my subconsciousness, and basically felt no drive to continue living anymore. Psychological suicide. That's what it felt like.

I will never, ever, repeat the experience. I'm considering even quitting therapeutic doses (50mg DPH, for sleep).
 
Chris Timothy said:
I combined 130mg MXE with 400mg DPH.

What was remarkable was that my heart felt fine. A little weak, but I did not experience torturous, sharp pains like I would when I'd dose 400mg DPH without the MXE. But to make up for that, the headspace created was absolutely horrible. The DPH delirium should not be experienced together with MXE lucidity. I merged with my subconsciousness, and basically felt no drive to continue living anymore. Psychological suicide. That's what it felt like.

I will never, ever, repeat the experience. I'm considering even quitting therapeutic doses (50mg DPH, for sleep).
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if 400mg of DPH felt horribly toxic by itself then why would it be okay to take it with something else?

the reason you didn't feel the pains this time was because MXE is an anesthetic first and foremost

p.s. hopefully you weren't attempting real suicide. that would be a bummer. and i don't even know you so believe me when i say it lol =p
 
thenightwatch said:
if 400mg of DPH felt horribly toxic by itself then why would it be okay to take it with something else?

the reason you didn't feel the pains this time was because MXE is an anesthetic first and foremost
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DXM/DPH combo's are usually less awful than DPH solo dosing. I imagined another dissociative could provide similar effects. Note that I started low and worked my way up, and only hit the proverbial brick wall at 130/400 MXE/DPH.

I'm not sure mere pain killing would be enough, in and of itself, to counter the DPH cardiac torture. I mean, does DXM work as pain killer in DXM/DPH combo's as well? My feeling is that the bigger picture is far more complicated.

But let it be clear that I agree there's nothing worth defending about DPH. It's a shit drug, and I present you yet another reason why.
 
Since seroquel is a 5ht2a antagonist and MXE doesn't work on the serotonin system, I can't think of any pharmacological reason why the two would interact. However, as with all drugs like Seroquel that cause a high level of sedation, I would expect it to dull the effects, at least. On the other hand, alcohol has sedating properties, but it can make MXE extremely nauseating. So, I would work up from a VERY small dose of MXE to find out if the combination is alright. Start with 5mg (I'm talking nasal dose here for simplicity) and work your way up. Space doses out at least 5 hours to make sure the doses don't overlap. Good luck!
 
Thanks man!! btw, do you think seroquel and 3grams of kratom would be dangerous?
 
I got told to post about this, i was going to earlier but i been lazy, anyway i'm sure this will interest you guys.
On new years eve i decided to take about 8mg 2c-e and 20mg MXE, i don't really remember much but it was pretty awesome.
Took a hit of nitrous at 12 when the fireworks went off, kicked ass, i had a revelation but immediately forgot it, but MXE ones are bullshit anyway.
Now after i wake up the next day i pretty much had the comedown visuals all week, every time i smoked some weed i got completely dissociated for like 5 seconds.
The post 2c-e dumbing down and memory loss was pretty bad, but after a week it stopped, the visuals and the 5 second weed trip stopped after 2 weeks, obviously 2nd week wasn't as intense as the first.
Anyway i think what caused it is that i have rapid CYP2D6 metabolisation, when i first used codeine i could get high on 30mg, if i take 100mg DXM and 50mg DPH i can get to 3rd plateau.
Seeing as though nobody else has had this problem, its quite possible MXE uses the 2D6 gene, maybe even 2c-e too.
 
Can't think of any major reason, however there are some (anecdotal) reports that suggest that MXE has the potential to GREATLY potentiate opiate drugs. 3g of Kratom is a very small dose, so I think the combination should be safe, but be careful!
 
Well its 3grams of "enhanced indo kratom". Overall I have 10gs of it which = 25g of normal indo kratom in terms of potency. So 5 grams = 12. something, and 2.5 grams is iquevelent to 6. something grams. Im going to do 3grams of the enhanced indo kratom with maybe 70mg mxe. Its 6pm now here, and i took seroquel at around 4.20pm (25mg), ill be taking the mxe+ kratom later tonight at around 10pm/11pm. Is it okay? thanks for your help, its been VERY useful.
 
10mg of valium not that long ago, 30/40mg of MXE up the hoofer, feeling a bit funky =D combines so well
 
Pars101 said:
Well its 3grams of "enhanced indo kratom". Overall I have 10gs of it which = 25g of normal indo kratom in terms of potency. So 5 grams = 12. something, and 2.5 grams is iquevelent to 6. something grams. Im going to do 3grams of the enhanced indo kratom with maybe 70mg mxe. Its 6pm now here, and i took seroquel at around 4.20pm (25mg), ill be taking the mxe+ kratom later tonight at around 10pm/11pm. Is it okay? thanks for your help, its been VERY useful.
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Well, to be honest, all I can say is that I'm pretty sure that combo will be safe (though, as always, I cannot be 100% sure). However, I cannot say with any certitude whether or not it will be pleasurable or comfortable. I would advise lowering the MXE dose for this first trial - 70mg is quite a high dose, especially in combo with an opiate when you haven't tried this combo. I would suggest at the MOST 30mg of MXE with the kratom and if it's not strong enough, you can always redose as MXE is quite amenable to redosing. You don't want to take too much because you can't really undo that; whereas you can always keep pushing the dose up.
 
Why are you on Seroquel? If you are prescribed antipsychotics, you should think very carefully about whether you want to take methoxetamine. The combination might not be inherently dangerous, but methoxetamine is a powerful drug, and I can definitely seeing it exacerbating a pre-existing mental health problem.
 
Had serotonin toxcitity myself, very unpleasent. Be careful, was like a living hell and felt like killing myself to make it end.
 
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