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Methoxetamine (MXE) - First Time - From An Experienced K Lover.

phatboy303

Bluelighter
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Jun 16, 2010
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Methoxetamine (MXE) retrospective trip report for last night (from the perspective a K lover):

First off, I have been sniffing K on/off for well over 10 years now, I'm a fairly big guy and have a reasonable tolerance (I don't do it every day though). I can't be bothered with any of this under the tongue or up the arse business, call me old fashioned but my nose has always been good for the job so I ain't changing now. I've stayed away from needles so far so I ain't gonna be trying this one injected either.

7:30pm: I decided to be sensible at first and sniffed 50mg in one line as that seemed to be the recommended from what I've been reading on here, sat round and gave it about an hour and a half, got some opiate like effects but no dissociation to speak off.

9:00pm: Decided to rack up another 50mg line, see what happens, over the next hour I started drifting a bit, some mild dissociation, kinda like K but different, warm opiate effects becoming quite pronounced. Colours seemed to get stronger and fuller in an opium way. Hands and feet became quite sweaty which was odd.

10:00pm (roughly): Not keeping up with time properly now but it was at least an hour after the last line. Racked up another 50mg in one up the nose, over the next hour or so I was definitely well on my way with the whole thing, some proper dissociation going and more of the opiate effects, but still nowhere near a hole.

11:00pm/12:00am (somewhere between the two, at a guess): I've really stopped paying attention to the time. Not sure if I'm feeling a bit let down by this stuff not being as strong as I was expecting or that I was starting to realise that my K tolerance is actually greater than I thought. Weighed up 100mg and split that into 2 lines. Whacked the first one up my nose, followed by the second maybe 20 mins later (I really am guessing with times now). Fuck knows what happened after that, I was absolutely twatted for a good hour or 2. Not quite the deepest hole I've ever been in but definitely passed the hole threshold. A lot like K but really quite different at the same time.

At some point after that second line, the Mrs decided (knowing what I'm like) to hide the rest of the bag from me so I didn't keep sniffing it, which for what its worth was a good call on her part but did mean that I spent most of the next hour looking for it and repeatedly asking her where it was and if it was safe. I was actually more concerned I'd lost it but inevitably if it was there I'd most likely have done more. I've since been told that it was like I had a 2 second memory, fair play to the Mrs for her patience and humour!

1:00/2:00am: (maybe, time had sorta become irrelevant by now): Out of the hole, dissociation wearing off, Lying in bed with the Mrs trying to watch a film, returning to a semi-normal state, opioid effects still lingering. Hands and feet still sweaty.

4:00am: K after-effects often keep me awake for a couple of hours but these are different, I can still feel some of the opiate stuff, I'm really quite awake and actually feel like I've had some sort of stimulant, albeit a mild one.

8:00am: Still fucking awake!!! Can tell the stuffs doing something although not much.

10:00/11:00 am: Got woken up the Mrs (I'm asleep on the sofa) getting up and getting ready to go out. Still got a sense of the MXE in my system, however off to bed and quite able to sleep but really fucking tired.

3:00pm Woken up by the phone, feel pretty much normal now.

Comparisons to K

This stuff is definitely comparable to K, its quite similar in many ways but also quite different in ways that are kinda hard to describe. I didn't feel like I was on any other kind of astral plane or anything however there were points where I wasn't really in the room either, the main difference is the opiate effects which brought a real warmth and glow to whole experience. I've tended to stay away from opiates through my life although I've tried most things but I would say a mix of good K and good opium might be a fair comparison.

In terms of strength, its definitely in the same ballpark as really strong K, maybe a little stronger. 50mg looks to my eyes like a decent, although by no means large, sized line (I'm personally a fan more of lots of little lines with K rather than doing one big fatty).

Duration of effects are a bit longer and the onset is a bit slower although not by a great deal. Duration of after effects however are a hell of a lot longer.

No particular feelings of movement that I find with good K, and as mentioned before it didn't seem quite as other-worldly or spiritual as a good K-hole can be (not that I'm the most spiritual person).

The sweaty palms and sweaty feet thing was quite unusual and quite noticeable, a little annoying even but not particularly unpleasant.

Serious issues for concern:

My main concern lies with the opioid effects, most obviously the possibility of serious addiction and physical withdrawal symptoms, definitely one to be careful not to do every day.

More seriously, the Mrs reckons I seemed to be short of breath at times while in the hole. She herself has breathing problems and she did 2 50mg lines over the course of the night (and a little bit of good old-fashioned K in between) following a bit of Mephedrone over the course of the day leading up to it. Having breathing issues herself she is very aware of her respiratory system and said that she felt like the MXE could be acting a serious respiratory depressant, unlike ketamine.

Giving that this stuff is more-ish in much the same way as K and is easy to get carried away with, we both feel concerned that there is a genuine danger in this and a risk that fatal overdose from some sort of respiratory failure is possible.

I don't want to end this report on a downer but its something that needs to be considered.

Final verdict

A really fun drug, one that I will definitely want to do again. K lovers will almost certainly get a great deal of enjoyment from this and I would happily recommend the experience to my friends (complete with warnings). If you treat this with care and respect and approach it as if you were going to do some really strong K you will probably be fine. Go easy on it though, seriously don't do any more than quarter gram in a night if you're like me (maybe less). Of course you know your own tolerance levels better than I do. Don't do big fat lines until you know what you are doing and seriously be careful about doing it too often or every day!!!

substancecode_methoxetamine
 
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That was a good report. I have a gram arriving tomorrow (hopefully), and I'm glad it didn't arrive last week when I ordered it. The opioid effects, combined with respiratory depressant is a huge cause for concern.

An overdose on this substance could be hugely similar to a heroin overdose, but the added dis-associative effect MXE has would leave you helplessly unaware of the slowing of breath. People may well die.

The fact that it is an opiate, and therefore addictive (and also probably builds up tolerance), can only lead to people taking MXE in increasingly large quantities and frequency, particularly as it can be ordered online.

Hopefully I'm just exaggerating the potential risks here, but if this is how MXE works, it should be treated with as much caution as any other strong opiate.
 
I've never noticed any shallow breathing but maybe that's more of an effect at larger doses. I'd be really quite surprised if it is a serious concern though as I think the opiate effects decline before the stimulation and dissociation wear off. Stimulation is the last of the main effects to go for me, other than some mild CEVs, if I get round to closing my eyes.

I'd be more concerned about some level of dependence. Along with the possibility of opiate dependence it's too much fun not to be slightly tempting to use on a regular basis.

Just my thoughts though!
 
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I've never noticed any shallow breathing but maybe that's more of an effect at larger doses. I'd be really quite surprised if it is a serious concern though as I think the opiate effects decline before the stimulation and dissociation wear off. Stimulation is the last of the main effects to go for me, other than some mild CEVs, if I get round to closing my eyes.

I'd be more concerned about some level of dependence. Along with the possibility of opiate dependence it's too much fun not be slightly tempting to use on a regular basis.

Just my thoughts though!

Knockando, I'm assuming you've used this substance on a few occasions. Have you noticed anything like withdrawals, slight dependence, or an increased tolerance? Or is the experience for you now the same as it was a couple of months back?
 
Speaking as someone who used to have quite a full-on K habit (I once sniffed a litre in a week all to myself) i know how easy it is to get carried away with things like this. K is the sort of thing people can quite happily sit around on their own and sniff loads, just worried doing the same thing with this could be risky.
 
Knockando, I'm assuming you've used this substance on a few occasions. Have you noticed anything like withdrawals, slight dependence, or an increased tolerance? Or is the experience for you now the same as it was a couple of months back?

I've used it every weekend except one for almost three months. I've noticed neither tolerance nor withdrawals. However F&B used it several days in a row and noticed mild w/ds.

I have been a disciplined doser up till now though, but having a massive bag in front of me may prove a temptation too far, I caught myself tucking in last night without weighing before I'd peaked from my original dose, and this is a personal no-no so I had to spit it out and dose properly! I'm possibly a bit obsessive with the scales but I love devices.
 
I've used it every weekend except one for almost three months. I've noticed neither tolerance nor withdrawals. However F&B used it several days in a row and noticed mild w/ds.

I have been a disciplined doser up till now though, but having a massive bag in front of me may prove a temptation too far, I caught myself tucking in last night without weighing before I'd peaked from my original dose, and this is a personal no-no so I had to spit it out and dose properly! I'm possibly a bit obsessive with the scales but I love devices.

Ahh that's quite reassuring. Really looking forwards dabbling with it tomorrow! :D Gona dose small and take things from there, since I have a whole gram to play about with.
 
The fact that it is an opiate

it is, ofcourse, not an opiate. even though it exhibits slight opioid activity (of which the exact mechanisms are still largely unknown), it isn't an opiate and imo it's also not very wise to label this as one. doing so might attract unwanted attention. also i don't think it's very wise to use 250mg of this on a first trial, regardless of previous disassociative experiences. oh well.
 
it is, ofcourse, not an opiate. even though it exhibits slight opioid activity (of which the exact mechanisms are still largely unknown), it isn't an opiate and imo it's also not very wise to label this as one. doing so might attract unwanted attention. also i don't think it's very wise to use 250mg of this on a first trial, regardless of previous disassociative experiences. oh well.

Surely if it acts on opioid receptors it has opiate qualities and therefore is an opiate?
 
Salvinorin A acts on kappa opioid receptors and it's not an opiate. I think the word is reserved for those chemicals which come from the Opium poppy and their synthetic analogues - those similar in structure; this isn't similar in structure.

I agree about the 250mg comment... there are going to be some unfortunate incidents if people think they can just bosh away at substances they haven't tried before just because they're used to something similar. There's plenty time, start with an allergy test, then a low dose (10-20mg) and work your way up. Low doses have pleasant effects too, why limit yourself to bright red all the time when there's a whole range of colours to appreciate.

Easier said than done I suppose!
 
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great report, I've been quite curious about substances similar to ketamine since I don't like the lingering after effects of K after a K hole. I may have to give this one a shot. only questions are, how was the taste of the drip and how was the burn in the nose?
 
Surely if it acts on opioid receptors it has opiate qualities and therefore is an opiate?

From dictionary(dot)com

1 opi·oid definition
Pronunciation: /ˈō-pē-ˌȯid/
Function: adj
1 : possessing some properties characteristic of opiate narcotics but not derived from opium
2 : of, involving, or induced by an opioid

2 opioid definition
Function: n
1 : any of a group of endogenous neural polypeptides (as an endorphin or enkephalin) that bind especially to opiate receptors and mimic some of the pharmacological properties of opiates called also opioid peptide
2 : a synthetic drug (as methadone) possessing narcotic properties similar to opiates but not derived from opium
broadly : opiate 1


Surely its reasonable to class this as a dissociative opioid (not opiate)
 
great report, I've been quite curious about substances similar to ketamine since I don't like the lingering after effects of K after a K hole. I may have to give this one a shot. only questions are, how was the taste of the drip and how was the burn in the nose?

No burn, very little taste. Quite a pleasant sniff really. Slightly dry throat that seemed like a result of the drip, but nothing major.

Didn't make me sneeze which K often does, and very little nasal blockage (snot buildup) afterwards. Wish more powders were that easy on the nose.
 
I think this will have a cross tolerance with opaites and ket... so double .... but overall a very nice drug.. relaxation of opiate and a little bit disoactive effect of ket... treat with respect
 
(i posted this in the main thread aswell, but since i started this one i thought i'd add here too)

The Mrs did some of this while I was out yesterday. Considering how responsible she was in stopping me getting carried away at the weekend, she very irresponsibily started sniffing it quite recklessly. She'd ran out mephedrone and since there was no K in the house decided that this would combat the fiending.

I can't be sure how much she took, but at a guess i would say 100-150mg over 2 hours. Her K tolerance is comparable to mine, although she's half my size. I'm only glad I got back when I did else she may have took more.

FWIW, she didn't really enjoy it, the mania effect didn't agree with her, in contrast to the more relaxing effects of K. By no means was she freaking out or anything but there did seem to be an air of panic about her. I took her out for a drive to get her a change of scenery/fresh air etc which helped although it took her about quarter of an hour to get her head round the concept of putting her shoes on!!! All in all, it didn't really last that long though, she was pretty close to baseline within an hour of me getting back.

She's fine now, reckons it wasn't very enjoyable and she probably won't bother doing it again. Like I said she can handle her K well and keeps up with me. Ironically, later that night we got a couple of grams of some of the strongest K we've had in ages and had a very nice time on it.

I know I've only been posting on here less than a week and it probably seems like we're a pair of fucking reckless twats, and you might well be right. Nevertheless we are both in our 30s and very experienced in the world of drug-taking. But we do both have a tendency to get carried away easily (i fucked up on MDPV the first and only time I did that, while the Mrs overdid it once on dimethocaine).

By no means am i here to scare anyone, but to repeat the points made earlier, this stuff should be treated with utmost respect. Regardless of the obvious comparisons with K and the fact that it has been marketed as a legal alternative to K, this stuff is not K and has many significant differences. Be careful.
 
Since that first report a few weeks back I've done a fair few experiments with this chemical.

As an old-skool ket-head, I've come to realise how very different this drug is. It's certainly its own thing and should be treated as independently as any other dissociative, irrespective of molecular similarities or marketing strategies.

Aside from the aforementioned opioid effects there's what I can only really describe as a kind of headrush type effect at higher doses, comparable in some ways to higher dose DXM or Nitrous, yet still kinda different. In comparison to K, sensory distortions seem to be less pronounced but still significant, motor functions and instinctual actions seem to be far more impaired. With K I find I have a sort of autopilot that I can generally trust to function pretty much normally and even perform various mildly complicated tasks, this autopilot is not so good on this stuff, couple of times I've been unable to even make a roll-up at the peak of MXE effects.

By far and away, in my opinion though the greatest difference here is the mania-effect (due to higher levels of DRI antagonism I believe, correct me if I'm wrong). This mania seems to have a really significant, somewhat OCD-like effect which, in the wrong person or the wrong environment, may well prove frightening. For many, like myself, this mania can be quite exciting but may seem odd or irrational to onlookers.

The Mrs has decided quite definitively that she doesn't like this drug and has no wish to ever take it again, she can be a touch on the OCD side herself at the best of times and this mania really doesn't play well with her. Personally I find that provided you have something to focus the mania on then its fine (me and a friend spent well over an hour looking at photos of caves online in a bid to find the perfect party venue). Again, what works for me doesn't necessarily work for everyone.

As far as dosage is concerned, for someone like myself with a fair old K tolerance, 50-100mg lines seems to be a good bet, with a dosage of 200-250mg total in one session as a limit.

I've actually found that infrequent smaller lines (less than 50mg per hour) can be quite pleasant as a little background thing, mild dissociation but with little to no visual/sensory distortion, allowing me to surf the web, watch telly and generally do anything I would normally do (with the obvious exceptions)

I haven't properly mixed this with mephedrone (Mortal Kombat-style) as I get a feeling this one could be quite dangerous, however I have sniffed this coming down from mephedrone and I can confirm that even tiny little bumps of this can be just as effective at combating drone-fiending as regular K.

I've also mixed this with K, I had some not-too-strong stuff that I decided to spice up with a little of this the other night and it sent me right off on one, simultaneously highly enjoyable and disturbingly wrong, definitely stronger than this on its own, but more like this than K. One to be careful with and, I would suggest, one for the more experienced ket-head.

As it stands myself, I feel like I have explored this one pretty thoroughly now, for all its nice quirks and shines, it just doesn't hold a candle to proper K. There is nowhere near as much depth to be found in here as can be found in a good K-hole, and once that initial novelty wears off this one seems very much like a one-trick-pony when compared to its adaptable, enlightening and multi-talented cousin. I can't really see me doing a great deal more of this, maybe the odd line now and then but that's about it.
 
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