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Methoxetamine Discussion Thread

Fairly simple magnesium strearate (chalk) is non soluable in H20 (unless heated to 2500 degrees c.) and If I didn't use micron filter (instantly clogged BTW) I would have IM'd a whole fuck load of magnesium strearate contaminated product into my leg. As The filter was fucked instantly I new something was up so did a subcut into my stomach and resulted in very localised compartment syndrome ie I had a hard lumpy boil at site of s/c injection. I actually hit them up about this and they were very unimpressed and basically told me I dont know what I'm talking about. I FUCKING DO! I had the balls to approach directly with query and they have been less than accomodating. I believe they are unaware of contaminate and have not added it themselves. This indicates the supplier is at fault with the contaminant and due to the different (less pleasurable effect) of the "Aussie" MXE it is obvious from a bit of research the supplier is chinese. Also to differentiate the chemical pharmacodynamic effect read any organic chemisty periodical journals etc. and have a search. I advise you to research and understand yourself about organic chem so you have all the facts. I can say xyz but unless you have a comprehensive understanding I may as well not waste your time and mine. MXE as has been stated activates MU opiod receptor (agonist/antagonis cant remember) and this is why taking opiods post MXE (proper MXE) is so much better. The other stuff I believe may be Tiletamine a white oderless disassociative not good if you have heart problems/ CNS problems ie epilepsy. This is just my personal opinion and chatting to a few UK mates and reading some pharmacological/organic chem periodicals. I may be wrong but I very much doubt it. Anyone else found this Aussie MXE is less enjoyable and tolerance builds greater than the brown Indian MXE? I don't mind either product just prefer MXE, I mean I was a raging K head at one point lol.
 
^ I've used European product from a well respected vendor and the Australian stuff, found both very similar in both potency and effects. And the effects of MXE on opioid receptors have not been proven and research done on other, similar dissociatives shows that binding to opioid receptors did not occur and so is unlikely for MXE.

I believe the effects it had on my tolerance probably had more to with NDMA antagonism; if it were truly an opioid agonist, you would expect tolerance to rise, no?
 
Yeah I went from shooting 50-80mg of morphine a night, had a weeks break with some MXE involved. After that week I almost couldn't finish a 25mg shot and I shouldn't have cause I was so sick for the rest of the day.
 
I hit the M-Hole big time... must have been around 100mg or more IR and I was taken to completely different worlds, forgot what day it was, lost all meaning of time and then was completely sucked into the music I was listening to. Should write a trip report but I don't know how to put most of it into words.
 
lovepsychadelics that makes sense now that you bring it to my attention in such a manner. I tried (and used quite heavily) the yellow product and found it much more "fun" than the white "chalky looking" product (supposed Aussie). I had actually commented a couple of times that when using nasaly it was like snorting chalk :/

Without going into specifics - I think it's a VERY good idea for everyone to stay away from the well known aussie supplier of MXE. This is not the first incidence I have heard of contaminated/diluted product from them. Probably turned into a sting operation by now anyway ;)
 
^ I highly doubt it is cut with chalk; dissolving it leaves hardly any residue in my experience and chalk is very insoluble in water. Snorting the stuff felt the same to me as snorting other European product, never had the yellow product though.

Anyway, I'm going to try and get an analysis done on the Australian product when I get a chance.
 
So how many people have a decent amount of IM/IV MXE experience? I've been doing it a fair bit lately and actually prefer IM, however Im scares the shit out of me so I usually end up IV'ing it.
 
Magnesium streate is a common additive octadecanoic acid sorry not thinking. It has melting point of 120 degrees. dont know what was up with my batch but it was discoloured slightly when disolved and had a chalky residue. Don't mean actual chalk but it was chalky texture etc. You can never tell if a RC batch has impurities or contaminants during processing or transport etc.
 
I had no problem with the off-white product from the well-known local vendor. Only tried IN and oral, had a slight numbing effect oral the first time but didn't notice it after that. Was very water soluble.
 
Sameria said:
Without going into specifics - I think it's a VERY good idea for everyone to stay away from the well known aussie supplier of MXE. This is not the first incidence I have heard of contaminated/diluted product from them. Probably turned into a sting operation by now anyway ;)
Click to expand...

Personally I don't have a problem with the new product (haven't tried to dissolve it yet), but will be interested in the results of any analysis.
Still, wise words above.
 
After much reading I have some MXE on the way! Very much looking forward to it as I loved my experiences with K... Used to get it in the mail years ago and it would totally shift my reality. One of the most appealing effects to me at this point is the dissociative/anti-depressant behavior, which I believe comes from the separation of one's self from the conditioned mind. Depending onhow much I like it I may invest in one of those expensive milligram scale beauties, got a cheap milligramer right now, but it's +/- 3mg :-P
 
yeah my cheap milligramer is all over the place, fuckng thing doesn't start reading until 0.4 then it seems to be out by a few 0.1
 
Yeah mine is sometimes out by 10+, pissing me off. I really wanna eat my 2CE.


There is a converting MXE to freebase tek over in the big and dandy if any one wants to try. I will be giving it a shot asap.
 
Jakeperson said:
There is a converting MXE to freebase tek over in the big and dandy if any one wants to try. I will be giving it a shot asap.
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Would you be able to post a link to it? I've tried searching and it's making me crazy that I can't find it, lol
 
Xavior said:
Would you be able to post a link to it? I've tried searching and it's making me crazy that I can't find it, lol
Click to expand...


I can do better

So, as prolly a few of you who follow the MXE scene are aware, there is a serious issue with product purity going around right now.

Is it salty or saline-like? Is it bitter? Is it sandy or crystalline or floury or fluffy? Is it yellow, off white or white like driven snow?

Dammit. We just want reliably pure MXE... But for the last three attempts a salty, MSG-like, hypertensive mix of junk has been all that has made it to us.

Analysis of this material shows that the organic extractable fraction is demonstrably MXE, but that the material contains LOTS of inorganic salts that are silent on NMR and MS. That way, the NMR or HPLC-MS looks clean, but on a per mass basis the recent materials received are laughably weak due to the inclusion of inorganic salts in the final products (intentional for purposes of profit, or due to ineptitude, who knows?).

Basically, the "bunk" MXE is salty, off-white/yellowed, granular or crystalline and sometimes has a weak, odd odor. Great MXE is fluffy, white, bitter like an amine should be and NOT salty.
Read on for details (tl;dr = basify, extract into organic, remove solvent, vape, smile):

It was first ascertained that the MXE was clean of appreciable organic impurities. It was secondly determined that the MXE material was contaminated with inorganic salts, and that the material provided VERY negative outcomes upon oral ROA. The insufflated ROA was also attempted once, and once only. Negative outcomes included soberness, hypertensive incidents, headaches, tinnitus and frustration.

* So, weak, yellow, granular, salty MXE was dissolved in distilled water and warmed until dissolved and the aqueous solution was clear and slightly yellow.
* Then sodium hydroxide was added, which immediately turned the aqueous solution opaque with suspended solids (insoluble MXE base).
* Hexane was added and the container shaken vigorously.
* The aqueous layer become less opaque (as MXE base moved into the hexane layer) and a nasty brown interface layer developed.
* Hexane layer was removed to a new container, and the aqueous layer was reextracted with another amount of hexane.
* Hexane layers were combined and the solvent was removed by evaporation until a minimal amount remained.
* A tube was tared, 1/5 ml of remaining hexane solution was added and the solvent removed by evaporation. The tube was reweighed and it was determined that ~21 mg of oily material was left in the glass tube after hexane was blown off.
* Remaining hexane was aliquoted into tubes and dried down in the same fashion.

=> As a ROA, a tube was heated with a lighter and the residue was vaporized/inhaled (~1/3 tube per session = ~7 mg).

Effects of vaporized MXE base, compared to MXE powder:

* Timeline: Effects manifest within ~1-5 minutes, and peak by 15 mins. It is STRONGLY suggested that at LEAST 20 minutes waiting/assessment period is inserted after each robust inhalation, or couple of weak inhalations... Effects can compound quickly to produce an overwhelming experience. Effects do not last as long as other ROAs, peak hits for about 20 minutes, appreciable comedown is achieved within 1 hour, and by 2 hours it's done.

* Quantitative effects: WTFROFLMAOBBQ. I'd say it's a tad bit more potent than what most folks are used to, when they go for a MXE experience. And by "tad bit" I mean "a million metric tons". For a frame of reference, remember that ~20 mgs makes it into the tube for vaporization. This is enough for ~3 powerful (but brief) sessions. Thus, ~6-7 mg MXE base vaporized will put someone on their ass, even with tolerance.

* Qualitative effects: COMPLETELY different than oral or insufflated. Vaporized MXE base is very rushy, manic, colorful, pushy and stimulating. There is no hole, at least from what we've seen... When one treis to get close to the M-hole zone the other effects of vaporized MXE (rushy, pushy, dopaminergic mania) come to the forefront and take over- preventing a hole from manifesting. It's also less visual, in that CEVs which are often experienced with oral and insuff MXE are not present for vaporized MXE.

So, although we're still hunting for the real, pure MXE... We can at least rest easy in the sure knowledge that our last three purchases of MXE baby do not have to be thrown out with the inorganic bathwater impurities. They will be converted to base and used for experimentation instead.

Up next in the utilization of MXE base is to add a few drops of vinegar to a tube containing ~20 mg MXE to dissolve and form the acetate salt in situ, followed by dilution into water and oral ROA. Will this provide the oral effects (Vaping MXE base gets exhausting after awhile) while avoiding the goddam toxic inorganic junk? We hope so!
Click to expand...

There ya go.
 
in regards to IM i find mxe pretty painless in comparison with 2cx

i would probably start at 30mg and work your way up, it is so great to feel the effects coming on in minutes

im probably sticking with plugging now though since last time i did IM i had to endure a trip thinking i had injected a cotton into my thigh :|
 
well, i tried sniffing mxe and it was soo nasty i had an awful time for about 30 minutes and a hurt nasal cavity. i usually end up iv'ing it, but i guess that is pretty unsafe, and ruins tolerance, but considering i only do it occassionally, i guess i was lucky.

I should move to IM or rectal. i dont know how one would use it sublingually, i think i would puke.
 
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