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Methadone doses of 100 mg or greater are more effective than lower doses

sl1p609

sl1p609

Bluelighter
Joined
May 18, 2008
Messages
156
Location
Costa Rica
Currently I'm at a Mdone Clinic, my Drug of Choice:
is Diamorph, H4 uncut coloumbian skag from Central America, and potent opioids ( fent, oxy, mscotin, hydrocodone )
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My name is Rafael and I recently joined a clinic in so-cal just this Month on the 14th
so its only been about 10 days, and today I increased my dose from 80 to 100mgs

My methadone dr. is a woman, short, asian, and always acting worried when I want to increase my doses.
she says " your so young and I don't want you to take high doses when we have to taper you off will be more difficult"
I say " I know my body and I need to be on this level because i have relapses and cravings " which is true by the way.....
I'm sure there are allot more patients here with ultra - high doses over 200.


I'd like to follow this scale becuase this is my first MMT and I trust this will help my over than 7 year addiction to opiates, street heroin and opioids
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lower-dose patients (20-60 mg/d) are for Opioid Dependence Physical Withdraw Symptoms
higher-dose patients (80-120 mg/d) are to block Psychological Opioid Dependence Cravings
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Until recently a 100-mg/d dose was regarded as a 'glass ceiling,' rarely to be penetrated. (wiki link)

this link below also shows another experiment with high doses increases stability

2005 Oct;100(10):1496-509.
Methadone doses of 100 mg or greater are more effective than lower doses at suppressing heroin self-administration in opioid-dependent volunteers.
Donny EC, Brasser SM, Bigelow GE, Stitzer ML, Walsh SL.
Source : Hyper Link

Behavioral Pharmacology Research Unit, Department of Psychiatry, Johns Hopkins School of Medicine, Baltimore, MD, USA.


p.s. please PM me or drop me a comment below and post your thoughts on this situation of mine.
 
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Doses that high are effective in the short term because they lead to quicker stability but it's better to stick with low doses and let it accumulate in your system. If you aren't in withdrawal then there is no need to increase the dose. The point of Methadone isn't to satisfy cravings, it's to eliminate withdrawal, stop the insatiable hunger for heroin, the anxiety, and allow you to work on the physiological aspects of sober living. The cravings will be there for a while because our body remembers the good feelings of heroin.

Going over 100mg is asking for trouble. The stuff accumulates in your system over time and when the time comes to taper off you are going to have a hard time. Additionally, a high dose is going to kill you libido, cause water retention, and lower your testosterone levels.

You can't expect to feel better after being on Methadone for only 10 days. It takes a few weeks to stabilize.

I have been on 100mg for four years. There are days where I still want to go get high but I don't.
 
Other Drugs caters to Methadone questions, so Im sure youll get plenty of answers there.

Im gonna shoot this on over there now.
 
Based off your posts man your not on MMT for the right reasons. You are still chasing a high if you want to increase your dose only after receiving it twice. You need to take a step back and reevaluate your intentions. Getting off methadone is no joke, I don't think you truly comprehend what your getting yourself into.
 
I think they want you to hesitate raising your dose so much because the less they have to give you then the more money they make. That's my opinion at least. But ya if you've only been on MMT for 2 days you need to slow down and let the medicine do it's job. It's not a drug that is going to get you high non-stop. The tolerance will soon rise and rise quickly. After that you'll only feel slightly sedated, relaxed and stabilized. You won't be feeling any sort of high.
 
I think that some people need high dosages in order to really give up using other opiates, as dosages over 70-80mg pretty much completely block there effects. Im currently on methadone for the second time at 50mg (not a blocking dose).

The last time I wast on MMT I went up to 110mg, and sure enough it blocked any possibility of getting high from heroin, or any opiate/opioid, including methadone itself. Though I would never, ever recomend anyone do so, I had at points doubled, even tripled my dose when I had the take homes necessairy to do it. I never got high, just sloppy and near death.

This time around Im choosing to not go above 50mg. The reason being that I'm a poly-substance abuser, so blocking opiates wasn't really my main goal when getting on the clinic (rather, I wanted to not deal with withdrawals and have something to help with cravings), as the last time I was on a blocking dose, I would just shoot cocaine which was a lot worse IMO.

I say, do what you feel is best for your recovery, just remember, someday you're going to want to come off of the stuff and at such a high dose, you're going to have to do a real slow taper or you're going to go through some really nasty and intense WD.
 
I'm sure I could find a hundred journal articles that disagreed with the single one you posted. Just because there's one paper published on something doesn't really mean a damn thing. Now if there are a hundred other studies that all come to the same exact conclusion, that's a different story.

I was on 100mg of methadone, but I still used other opiates all the time, it really didn't help at all with my cravings. Then a few years down the road, I was only on 20mg of methadone a day. I tapered, switched to bupe and I'm 6 months clean from opiates.
 
it worked because it totally blocked a shot of black tar that i slammed.. i use high doses to keep me in line and have enough time to think .. .
shit

im not chasing a high nor anything of that nature. I have done doses raging from 5mgs, 7.5 and 10mgs per 24hrs also 20-50mgs..

right now im not in a good area, i lost most of my teeth and shit.. but im not getting into this "DarkSide part"

this is just for me .. food for thought
 
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