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Opioids METHADONE: Cracked it! Found a way to beat the slow onset of methadone

Niksput

Greenlighter
Joined
May 22, 2012
Messages
26
Hi all, looooong time lurker, new poster really.

i'm on 80mg of meth (liquid UK sugar free solution) and I bet you all know that feeling of clucking bad and the meth is taking 90 - 120 mins for just a tickle of relief, well i've been experimenting.

DAY 1: Downed 250ml of sugared HOT water (i thought the sugar free version of my meth may have affected it somehow). When I say HOT, i mean to the point it's uncomfortable.
Result: Full effects within 45 mins.

I then realised i was dealing with a linctus, and codeine linctus has alcohol in whereas methadone linctus has chloroform.

DAY 2: 10ML of 40% vodka (less than half a shot) again in JUST drinkably water temperature wise (250ml followed by another 100ml of the same temp - I estimate 70 degrees C?)
Result: Potentiation of around 1/3, full onset of effects in 25 minutes - itchy nose, euphoria, sleepiness - basically what normally takes 2 hours to start working for me.

Now this may not work for everyone, everyone has different meth, different bodies etc, but for me, i've found it. I had a problem where the more days in a row I took my meth, the less potent the high until Saturday when i'd get a takehome and drink all 160ml. Then because Sundays dose is gone and I go into minor W/Ds the Monday dose hits me much harder. This method i've described seems to have overridden any tolerance issues, and if you're like me and are impatient with your meth, give it a go.

Also: ALWAYS have an empty stomach. I took 160ml once after a KFC and got nothing, whereas i'm normally nodding off that hard. Empty stomach all the way.

Jake
 
None of the methadone solutions use chloroform any more 'cause it's a carcinogen. It's just methadone HCl, color, sweetener, flavors. The british DTF formula is like that. They don't even use alcohol either, just propylene glycol.

My prescribing nurse is talking balls then, he said only the clear stuff in AUS hasn't got chloroform and they bang their meth over their because of it. He told me here there is about 0.015% chloroform to cuase a burning sensation on injection. I am DAMN sure our meth contains parahydroxybenzoates (nasty, listed as E numbers in the UK, always made chugging a bottle of what Americans call "lean", really, really hard. But i'm "England style yo'", so did it anyway. Anyway I would've thought they'd be in my meth, especially because it's sugar free (diabetic) linctus, just because all sugar free linctuses i've had before (codeine, dihydrocodeine in AUS, morphine etc) had these parahydroxybenzoates (preservatives apparently).

Still, back on topic. I just dosed my meth T 9.09, did my little recipe and got a little rush like feeling at 9.34. It works guys, for me anyway, what's the harm in trying. I must insist on HOT water though, the hottest you can handle. If you're the kinda guy who can drink a cup of coffee straight from the kettle that would be ideal. I can't so I go by the max of my tap (thermoteter mesures 71 degrees C pretty often). Try it, why not? It's worth a go surely, and i'd love to help some of those out who are pissed about the long onset time of liquid meth. (With pills there are other ways but that's not good discussion nor HR so i won't go into them. You can probably guess what i mean from me saying "not HR").

Jake
 
None of the methadone solutions use chloroform any more 'cause it's a carcinogen. It's just methadone HCl, color, sweetener, flavors. The british DTF formula is like that. They don't even use alcohol either, just propylene glycol.

Ah.. Read p6.1 of the link you sent me:

6.1 List of excipients


Sucrose, propylene glycol, methyl hydroxybenzoate, propyl hydroxybenzoate, liquid maltitol, tartrazine E102, sunset yellow E110, green s E142, poloxamer 188, simethicone emulsion 30% and purified water.

There's those hydroxybenzoates again!
 
I could try the hot water thing, but my methadone always starts hitting me in full at the 40 min mark. If I have a lower than usual tolerance and extremely empty stomach, then I can notice first effects from 25-30 min.
 
I could try the hot water thing, but my methadone always starts hitting me in full at the 40 min mark. If I have a lower than usual tolerance and extremely empty stomach, then I can notice first effects from 25-30 min.
that's about how methadone effects me too. If the dose is high enough for me to feel anyway though I'm interested why the big gap. I know each brain is different but that's quite a difference in metabolism time.
 
It has nothing to do with the brain, and everything to do with how fast the methadone gets into your BLOOD (which then enters the brain). There is a ton of natural variation for factors such as stomach contents, gastric emptying time, speed of absorption and temperature, extent of first pass metabolism as the drug enters your liver before getting into your blood (this is where the biggest differences in metabolism occur, as there is high variation of CYP450 enzyme (CYP3A4 and CYP2D6 mainly) which metabolize and eliminate methadone. So someone with an empty stomach, fast absorption time and normal to low levels of CYP in the liver is likely to feel their methadone faster than others. Metabolism is more of a factor in how long the drug lasts, and not initial uptake however.
 
The liquid methadone hits pretty fast for most people.. I feel it within 15-20 minutes of dosing. It doesn't reach peak levels for about 2 hours, but that doesn't mean you're not still feeling it.. and depending on your dose.. sometimes very strongly.

I've seen people at my clinic, nodding out in their chair just 20 minutes after dosing..

So maybe you're just a very slow metabolizer of methadone.
 
i agree with you it takes longer to kick in. But last so long its worth the wait. Only thing is once you get on it nothing else will break through it. You wont get off on other stuff for like weeks after the last dose. I was on it 7 years and when i came off. Sucked so bad cause nothing helps. I also think it is harder to kick than the other short acting ones. I love dolly but also have to hate her. And i do know of one dude who used to send the 10mg coffins up the main road. And it would hit him faster thats no lie but the 40mg never seen em done because the amount of liquid needed to... well you know.
 
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