Mescaline and Abilify: Help!

[Corporatedroneguy]

Greetings,

For the past two months I have been taking abilify in 5 mg tablets daily to help with a case of mild depression. I feel mentally stable, so while I understand concerns regarding whether I should experiment with psychedelics in the first place, I will kindly ask that you please do not bring them up. I've given this much thought and I know I have a good mental set for a trip. So here's my predicament..

As I mentioned earlier, I'm taking 5 mg of abilify daily. It has a 75 hour half-life, so that means as of two days ago-when I stopped taking my abilify-I had 31.25 mg in my system. According to my calculations, by next saturday I will have 5.5 mg in my system, and by the saturday after next I will have 1.61 mg in my system. The psychedelic I have chosen to use for my trip is mescaline, contained in a Peruvian torch cactus.

Do you guys think that 5.5 mg of abilify in my bloodstream is enough to agonize my 5h2a receptors to a point where the mescaline will not have a significant effect on me? What I'm most concerned of is the marginal decrease in the effects of mescaline per mg increase in abilify. I would appreciate personal experience as well as scientific insight. Thank you!

P.S. sorry for any ignorance on my part. I know this isn't the correct area to post this, but in the appropriate sub-forum no one is responding. Please correct any mistakes I have made.

 

[Ismene]

I've no idea if it would have any effect on the trip. My best guess is probably not.

Have you ever tried taking cactus before? It's a very, very difficult thing to drink enough cactus sludge to actually get past threshold effects. Good luck.

 

[Corporatedroneguy]

I haven't tried it before. I'm gonna extract it in such a way that it's only about 2 shots of liquid. Shouldn't be that bad.

 

[any major dude]

Well, aripiprazole is a pretty potent 5-HT2a antagonist, and I know mirtazapine, also a 5-HT2a antagonist, has been used effectively to abort trips. So it may well decrease the effects of mescaline, but there have been a few scattered reports of mirtazapine potentiating psychedelics as well. It may have something to do with the length of time one has been taking mirtazapine & the effect on relevant receptor expression. Think we're in mostly uncharted territory here as aripiprazole hasn't been around very long at all. And typically the subset of the population that is using it doesn't use psychedelics... anyway, good luck & tread lightly

 

[dionysus]

Like I said, I have taken mescaline on abilify. I was on 15 mgs for a long time at that point. And it didn't affect anything. I took about a foot to a foot and a half of San Pedro cactus. But a mescaline trip can really vary depending on the cactus. Are you sure it is psychedelic? Have other people you know tried the same cactus? If it is verifiably psychedelic and you know what you are doing as far as cooking it then you should be fine. 5 mgs of abilify is an extremely low dose and mescaline is a powerful drug so i doubt it would be counteracted by the abilify. The best way to experiment with mescaline is to do it. I am sure you will be fine. I did it twice while on abilify and like i said I tripped pretty good. Well safe tripping and have a good time. Later.

 

[Corporatedroneguy]

Like I said, I have taken mescaline on abilify. I was on 15 mgs for a long time at that point. And it didn't affect anything. I took about a foot to a foot and a half of San Pedro cactus. But a mescaline trip can really vary depending on the cactus. Are you sure it is psychedelic? Have other people you know tried the same cactus? If it is verifiably psychedelic and you know what you are doing as far as cooking it then you should be fine. 5 mgs of abilify is an extremely low dose and mescaline is a powerful drug so i doubt it would be counteracted by the abilify. The best way to experiment with mescaline is to do it. I am sure you will be fine. I did it twice while on abilify and like i said I tripped pretty good. Well safe tripping and have a good time. Later.

Thanks for your input. This is my first time trying cactus, so I have no idea if it's psychedelic or not. I think my extraction method should work and I'm using a little more than a foot of a cactus with a 4 inch diameter, so I should be good. I messed up my original calculation of how much abilify would be in my system by next weekend. I originally said about 5 mg, it turns out it will be 1.84 mg in my system. I'm hoping that doesn't significantly effect the trip in any way. It's encouraging to hear that you tripped while regularly taking 15 mg of abilify. How was the cactus trip? I've heard good things about it and I look forward to my experience next weekend. Wish me luck!