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  • EADD Moderators: Pissed_and_messed | Shinji Ikari

Mephedrone Megathread VI: Anyone Seen My Heartvalves?

Well, it's my guess it causes cardiac fibrosis as a possible 5HT2B agonist and 5HT releaser. That is, the inappropriate proliferation of fibroblasts causes thickening of the heart that is generally a chronic condition and can predispose someone to cardiac failure. This is especially true if they continue to abuse stimulants and use them on a regular basis. Coupled with the probable induction of pulmonary hypertension from the drug, things could get very dangerous if it's used often.
 
I can't find it, I'm going to edit what I wrote so I'm not propagating bullshit, sorry guys.
 
Hmm

im worried about the heart issues, esp since i dont think mine is very healthy already, hit meph pretty hard, havent done for a week, getting a g tonight with a few beers then im done i dont want to drop dead from it its not worth the risk.

keep seeing these types of comments "I'm worried but I shall do one last G tonight/this weekend" etc.

What is it about meph that keeps some people coming back for more and more even when suffering sideffects or concerned about them.
 
I have done 1 gram a week for the past 11 months and never have had any nasty side effects.
I never even notice by heartrate raising, but being a stimulant I am sure it does.

A couple of my mates feel rough the next day or 2 but they have also been using MDMA, speed, coke, hash, alcohol or something else with it.
I just stick to meph and don't mix it with anything and I don't smoke anyway.

Also I will bomb 2 lots off 250mg one night and then stop and make sure I get some sleep that night.
It's only when I have missed sleep that I feel weird the next day, I think dreaming is very important and when we miss this out for a day or 2 it can mess with our sanity, energy and general feeling of well being.

I know I would get the hangover from hell if I mixed meph with alcohol, speed or hash.

I learnt from previous experience, I was a late starter compared to some on here but I first took MDMA in 1994, that was the first time I ever took a drug.
I was hooked straight away even though my mates told me it was not addictive.
So because I wanted to experience that euphoria that was better than anything I had experienced in my life (past and future) I took it every single week, 3 times a week because I did not have any information on how it worked and did not know the stupidityof doing it that often. This was before I had access to the internet.
Tolerance built up, hangovers got worse and worse, MDMA stopped having an effect of me so much so that I would blame the pills, but others would get mashed off the same ones.

If only I knew then what I know now thanks to this website.
 
And would your best friend be happy for you to drop 4 or 5 'pills' not knowing what they are, just because you were told they were 'mad pure MDMA'?

Or how about having some coke which is likely about 5 - 10% actual cocaine?

The thing is, at least with this you can be pretty much certain of what chemical you are putting into your body. This allows you to look at the growing body of evidence about it and make an informed decision. You can't say that about many of the illegal substances because they are almost never of high purity.

I'm also glad that people are starting to realise that there is a downside to 4-MMC, because everywhere you go people are taking it to an abusive degree and this needs to stop as soon as possible.

But, given how widespread use of this is (and we're talking tens of thousands of people using it every weekend) the fact remains that there are relatively few dire complications being brought forward. That doesn't mean that they aren't there - but it's important to look at them rationally and in perspective, particularly on this forum.

Like most things, moderation and education are what's needed.

p.s. scarring of the heart? that sounds like something worth looking into - source please.

Depends on who told me the pills were 'mad mdma' ! They were taking into consideration my addictive personality matey and looking out for me. They know all too well where it would end up if I started on the stuff.

My educated and rational decision is to keep away from the stuff - end of really.
 
FFFFFFFFFFFFFFFFFFFFFFFFFFUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUU--

Not even goddamn dopaminergic goodies work >___<
I barely feel really good blow ;__;

So, 3 weeks since my last dose, I'm going to start a regimen of:

100mg 2x daily 5-HTP (3 weeks)
l-Tyrosine (2 weeks)
Multivitamin (3 weeks)

We'll see how this pans out...
I am SO sick of only being able to get high on opiates and JWH and Ketamine ;______;


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AHHHHHHHHHHHHHHHHHHHHHkl'asjhdkl;ashd
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i know countless people taking about a gram a day, they don't seem to give a fuck about they're health, i dont understand why they dont get severe come downs though. perhaps its because i mix it with booze

either way im getting rid of all my mephedrone tonight

for some reason i think i will end up doing it again though... when ive had a few drinks i get the urge to do some.... when i fully recover i always think "ahh, wont hurt just this once. then ill never do it again " sadly that never seems to be the case.

my heart still feels weird now
 
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for some reason i think i will end up doing it again though... when ive had a few drinks i get the urge to do some.... when i fully recover i always think "ahh, wont hurt just this once. then ill never do it again " sadly that never seems to be the case.

my heart still feels weird now
It's like smoking. I know it's killing me. I cough, and my lungs feel weird, but it doesn't stop me lighting up again. It's crazy that mephedrone seems to be as compulsive and addictive as cigarettes.
 
I can't say if Mephedrone made me not care I was killing myself or if I didn't care in the first place. I'm not taking anything to at least try and do something to my heart and those supplements are only so I can get high on other drugs again.
 
It's like smoking. I know it's killing me. I cough, and my lungs feel weird, but it doesn't stop me lighting up again. It's crazy that mephedrone seems to be as compulsive and addictive as cigarettes.

Meph > Marlbrough's :)
 
my heart still feels weird now

Have you been to a doctor for a checkup? One thing I have noticed is that lots of people go to the doctor and they are told 'everything normal'...even though they don't feel like it is.

I wonder if there is a psychosomatic aspect to the heart issues? Not trying to dismiss the very real concerns at all, just a thought.
 
i know countless people taking about a gram a day, they don't seem to give a fuck about they're health, i dont understand why they dont get severe come downs though. perhaps its because i mix it with booze

either way im selling all my mephedrone tonight

for some reason i think i will end up doing it again though... when ive had a few drinks i get the urge to do some.... when i fully recover i always think "ahh, wont hurt just this once. then ill never do it again " sadly that never seems to be the case.

my heart still feels weird now

That sounds like a good idea mate, get rid of it and don't do it again.

I would not do drugs if it made me feel shit, like Methylone does to me.
I'll never touch that again.

I remember I snorted coke in 1999, it made my heart pound and I became paranoid, all my mates noticed the paranoia about the slightest noise outside etc. I have never touched it since.

Meph does not give me a pounding heart or paranoia or purple limbs, if it did I would not do it again.

It could of course be causing fibrosis to my heart valves, I wont deny it could be happening.
 
Have you been to a doctor for a checkup? One thing I have noticed is that lots of people go to the doctor and they are told 'everything normal'...even though they don't feel like it is.

I wonder if there is a psychosomatic aspect to the heart issues? Not trying to dismiss the very real concerns at all, just a thought.

They just cant "measure" severe vasoconstriction.
 
ok ive gotten rid of all my meph. ive given it to a lady who will abuse it, ive warned her about the side effects. just like i warned my cousins boyfriend who ended up going on a 4 day bender with no food and no sleep, only to end up a sweating crazy mess. if she ends up in that state then well.....i warned her. if the people i know thinks they know best after using it for a month, as apposed to my 6+ months usage, and reading everybody else's reports on here, then let them carry on and fuck themselves up,

anyway,

its abit sad because alcohol for me now will be boring and shit without meph, especially at raves and clubs - as i only did meph with booze. so its like a brain link, like alcohol and cigarettes, the desire to do it will be nagging away. the incredible way music sounded, the lights, the feeling, the jaw grinding, the weightless amazing body feeling, the eye wiggles, talking rubbish, watching people dance, it was beautiful. booze isnt bad, but after drinking for years its shite on its own. although at least it doesnt give me weird side effects, just a nasty hangover.

if i go to a rave i bet ecstasy pills now will all be cut with meph - if not entirely meph. or something else, which is why i wont touch ecstasy or cocaine or any of that.

meph will be like an ex.......... nasty, nasty bitch who will love me, then mess me up............. but still want her...... even though i know shes bad
 
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Have you been to a doctor for a checkup? One thing I have noticed is that lots of people go to the doctor and they are told 'everything normal'...even though they don't feel like it is.

I wonder if there is a psychosomatic aspect to the heart issues? Not trying to dismiss the very real concerns at all, just a thought.
You seem to argue for meph in most of your posts. It's strange you don't add to any other threads. Is there a reason for this? I'm sure all these symptoms are just in people's heads. Keep on hammering it, people! 8)
 
You seem to argue for meph in most of your posts. It's strange you don't add to any other threads. Is there a reason for this? I'm sure all these symptoms are just in people's heads. Keep on hammering it, people! 8)

Also, there are pictures posted in the how toxic is mephedrone thread of ppl with purple knees, sure thats all in the head;).
 
Of course. Have you never made your knees turn purple with your mind? ;)
 
It's strange you don't add to any other threads. Is there a reason for this?

Yeah, because I'm completely deluded and full of shit ;) I do add to some other threads, but I'm interested in this at the moment. I tend to get rather...focused like that.

You seem to add to every thread...is there a reason for this? :\

I joined here because I saw that all of my friends were taking meph, so I became interested in it. Since then, I have done it once and enjoyed the experience. Will probably do it again, but have been mostly interested in just how serious the toxicity is and how to diminish any negative side-effects.

I've never denied the fact that there are negative side-effects, but I am just interested in both sides of the story. I don't think either side pro or con knows much about this substance at all, so just because you are con-meph doesn't mean you're going to be right about everything 8)

As for the psychosomatic suggestion, it was just a suggestion. I find it most interesting that you won't even consider it and instead jump onto the 'but they had purple knees!!! purple knees!!!'. I do believe that there will be some people who misconceive the typical response to a stimulant (i.e. elevated heart rate) and create the idea that something is wrong with their heart, which leads to further anxiety, which they then contribute to the substance/metabolites.

Just trying to have a conversation that doesn't immediately end with either a) 'meph is really evil and toxic and you're an idiot for taking it' or b) 'OMG rushing sooooo hard right now meph meph MEPH!'

Consider alternatives all the time, 'because only the mad man is absolutely sure'.

And please, don't treat me like a moron.
 
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As for the psychosomatic suggestion, it was just a suggestion. I find it most interesting that you won't even consider it and instead jump onto the 'but they had purple knees!!! purple knees!!!'

I am not sure where it is now but back when this purple knee phenomenon was first reported i (and likely others as well) suspected it was the result of panic and suggestion and managed to get someone to post a picture of their knees looking a quite worrying shade of purple in response.

I find it more likely the colour i saw in the photo posted was the result of drug metabolites or some other real (biochemical) drug effect than psychosomatic suggestion.
 
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