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Mephedrone cardiotoxicity - ingestion VS insufflation?

W

wondersoup

Bluelighter
Joined
Jul 29, 2009
Messages
48
*****warning**** Please do not attempt to imitate the dosages in this post. This is a research chemical and I am very ashamed of my doses. so little is known *******

Hello there, I have been a user of mephedrone for a while now, always been very careful with my dosage.. but naturally the fiendish nature of this chemical it sort of increased to experience more of the euphoria ( I love entactogens.. and with most mdma being passed off as crushed bzp where around here.. it simply isn't an option)

I have noticed however with these higher doses (sometimes 500mg ingested at once - yes... awful.. please don't get mad) that I simply do not get the chest pains or increased heart rate that people have been complaining of.. neither does my partner who is equally as naughty. Just intense rushes of euphoria, some empathy and lots of talkativeness. We have had sessions which between us.. that have gone through nearly 6-8g in 1-2 days.

After reading the awful, awful mephedrone horror stories I was naturally terrified this would happen to us, so I immediately was checking heart rate, looking for those scary purple marks and trying to notice the mildest chest pain after every session.. which just hasn't happened (could be a biological difference in me - who knows) as for my partner she has an irregular heartbeat (non serious) so I was naturally scared for her. She has also been completely fine in all the months we have have been doing this R/C. No chest pains/ tingling to speak of.

This has lead me to wonder... both of us only ever ingest mephedrone via capsules we make ourselves , washed down with a drink. I cannot stand shoving things up my nose as my sinuses are generally total shit - the smallest line will leave me sneezing for hours.. if I'm stupid enough to have a coke binge it will give me a week long cold where i am still sneezing up coke that never went anywhere. Alot of the mephedrone horror stories seem to have snorting in common and I would like to hear from people who had bad effects just from ingesting large amounts solely to disprove this? or maybe a someone with a better understanding of biochemistry can explain whether this has standing or is total crap?

Another factor that could contribute is sometimes we ingest GBL and sometimes viagra during our mephedrone binges for the best sex I have ever had in my life (seriously ... I am in pain afterwoods) Both of which are known to lower heartrate... which leads me to wonder if that is counteracting in some way?
 
This is quite interesting. i've never really experienced any dramatic increase in heart rate or any color-changing of the skin or anything like the horror stories described...yet...and i've only ever insufflated, but it hasn't been that much, most i've ever done in one session was ~750mg. I do plan on just downing some next time i get it. I'm interested to compare the two MOA's.
 
My GF only ingests and she ingested about 350mg the over night and went white. She loves the stuff but it seems to me that some people's reactions are more intense. I have dropped a lot .5g before and felt ok. Heart back to normal next day! I even snort the stuff to boost.

I am sure there has got to be something like a dodgy gene (lack of enzyme) making this really bad for some people.

I am interested to know how viagra helps tho. I am usually horny but I cant get it up and she is usually wet but not mentally horny (too fucked!).

Bombing seems to be better. It seems as strong and lasts way longer.
 
DO NOT COMBINE STIMULANTS WITH VIAGRA.

It greatly increases the risks of cardiac problems. This is just plain retarded and anyone who isn't aware of it should not be playing with research chemicals. It is just a matter of time before we see another few deaths attributed to this chemical and it will be ruined for everyone.
 
^ Even worse is mushrooms.

Mixing liberty caps with Viagra just gives you a neon-coloured compulsion to wank.

Honestly.
 
theWorldWithin said:
DO NOT COMBINE STIMULANTS WITH VIAGRA.

It greatly increases the risks of cardiac problems. This is just plain retarded and anyone who isn't aware of it should not be playing with research chemicals. It is just a matter of time before we see another few deaths attributed to this chemical and it will be ruined for everyone.
Click to expand...

For anyone with heart problems....I'm not saying that it is %100 safe for anyone to use this combination, but there was study on MDMA mixed with Viagra and drugs like it that, and the conclusion was that they greatly reduced the toxicity from MDMA.

PLEASE DON't USE THIS COMBINATION WITHOUT HAVING YOUR HEART HEALTH EVALUATED.
 
I am also not proud of my doses but have always kept my hr highly monitered and observed skin for any signs of serious vasoconstricition every time i touch this.

i have taken 3 g over a period 20 hour period by no means a regular occurence it was a rather good musical event.

However as i said i have never had any negative affects gennerally my heart rate stays withi 20-30 beats of my resting even at peak despite this i will be very high.

Also my friens who all obtain it rom the same source also experience no real adverse effects a moderate come down but no really high heart rates and no worrying vasoconstricition.

Tis is just a theory but would there be differences between batches maybe incomplete reactions etc that could cause these negative effects, maybe a cutting agent?

or it may be purely genetic as for me it is much more intense than MDMA while my fiend says it is nowhere near as strong for him
 
yeah the chest pains seem to come when you ingest over .5 g, mix with other drugs (including OTC and yes caffine), or use more often than once every 5 days. another thing that causes chest pains is smoking it. it smokes good then recrystalises in your lungs and makes you feel like theres a clamp on your chest for about a day and a half.
another thing is it tends to people who abuse drugs more often that get it. and compared to what fate testing rediculousness i did you have been using it safely. i'd say just never go above .5g and never do it more often than you originaly planned on and you'll be ok.
also insulfation is nice and more cokey but the come down is so so much worst, it's realy more of a let down. honnestly it's not worth it.

I some how consumed 2.3 grams in 48 hours. went 54 hours no sleep and started suffering from seratonin psycosis. luckily a fair amount of my friends are into psycology and were able to rebalance the chemicals in my brain but that is definantly not some thing i want to do again. I literaly felt like i was being choked to death by an invisible hand(from the dehydration) but couldnt stop.

I honnestly can't believe i didn't die. and mephedrone sex is AWESOME!!!

another MOA you guys might think about trying is letting it soak in through your skin. i did this to ease the come down. you put about 100mg on your wrists , lick them and rub them together, they should go numb and you should start gigiling in about 5 minutes.

but in reguards to the cardiotoxin, all it needs is a hydrogen to link onto that double bonded O and BAM it goes from fun drug to poisionous cardio toxin.
 
Captain.Heroin said:
I haven't tried IV mdma, but I have tried IV MDA. And I don't think anything could beat that (other than maybe a high dose DMT trip? I haven't even tried DMT and that's what I expected DMT to be like when I IV'd the MDA)
Click to expand...

Funnily enough, I actually scored 2 tiny wraps of DMT a few days ago.

I wouldn't call it (DMT) recreational at all - and certainly nothing like MDMA/MDA/ COCAINE !!

It makes LSD look like weetabix.
 
Ok so me and my bf took this about two days ago. First time i've even heard of it. We were trying to originally find Molly or tabs of any sort but no luck. Randomly someone said this stuff "drone" was just like molly but a bit more speedy.
Eyy I wouldn't really call it molly. X is a top fav on my drug list. Only if it is good. Must say this drug is amazing in diff ways. It's great but i'm not really sure it is anything like molly but still good. My bf however compared it to like his first time rolling and the best thing ever. Wish it were that good for me. Sex however yes is much better then molly sex.
A problem I noticed though was that we had 2gs and pretty much said we were going to do a gram between us and save the rest for our friends. Well... next thing i know we are debating on what to do with the last .5. Either split it and take some before work or save it and deal with the day of no sleep. Ofc we ate it all. Suddenly we picked back up and were gone out of our minds. No school. No work. Two days had past and wow... still wondering did all that really happen? Luckily he didn't lose his job however it was a close scary call.
Idk if i'd mess with it too much because the craving it scares me. I had less control over it then coke. If we are to do it again we have already decided a day when we both have nothing to do tmw.

Did any of you guys have the problem with stopping?
 
I have read reports of people redosing a lot, and going on binges with mephedrone.

It is to be expected with stimulants though.
 
Yeah. I mean at the time I really wasn't too sure on what it was beside it is like Molly... Checked on Erowid and quick info so seemed legit. Which it was don't get me wrong. Did it again and that time was almost the same.
I don't really care thought now. Doesn't bother me at all. Most drugs don't though. I don't really consider myself of having an addictive personality. It just surprised me that we couldn't stop while we were on it. This site however helps out a lot. :)
 
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