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[MEGA]Synthetic Cannabinoid Discussion- 2nd Toke

lololol, ow my head. Who do you think pays for University studies? The government. Check out the psyc research opps and psychinfo.com and psycsearch. good luck finding any real studies on any of these compounds, it'll be a long time before any of us is able to determine what is "safe". None, that would be "safe". Also, relative weight/dosage information, which I doubt you will find, is a joke when talking about lab rats. Completely different everything, and this is not a psychoactive chemical that is causally linked to dosage/size - 15mg is 15mg regardless of if you are 4'7 or 5'11

I use 100% acetone, instead of everclear. Agree with most of what you said besides that last part, that's just fooling yourself. These are RCs - RESEARCH CHEMS. Don't be too shocked if you grow an extra pair of tits.

actually there are plenty of legitimate University studies involving psychoactive synthetic cannabinoids including (the JWH and some of the AM series) Alzheimer's both in the States and abroad (a side note not all educational institutions in foreign countries "get their money" from government sources, privately owned and operated for many generations), eating dis-orders, as well as Neurovascular research, but what hasn't been studied so much is the MPPP (like one of it's newer derivatives ZZ-1 found in the now "legal blends") designations due to it's link to Parkinson's by the impurity MPTP in the late 80's early 90's, now that all the JWH-xxx designations become analogs and banned by stricter state laws than the federal law vendors are looking for the next legal thing, in this case an opioid instead of a cannaboid, something people should know, IMHO.

BTW coffee's ingredient is considered a psychoactive chemical....and HOW exactly do cannabinoids or these recent legal opioids NOT fall under that category and be directly related to dosages in studies? lol indeed.

I do agree tho, that " it'll be a long time before any of us is able to determine what is "safe". ten years was not enough, and much more can be learned on the lines of legitimate research that can benefit mankind.
 
hmm, Marinol/Dranibinol seems to be FDA approved for nausea that can not be controlled other wise. lidocaine and milanta, along with IV nexium didnt do nothing in the ER, neither does promethezine, ratanadine, and another i forget.

this is news to me, my doc tried passing it through my insurance this time last year as, in "several ways" he said - this would be sooo massive if it does happen.


goes back for honey tincture and another joint - $$$
pissing it away...
 
I had an interesting experience last night smoking a blend with am-2201 just curious to know what this possibly means.

I smoked 3 bowls of a high potency spice blend and had a psychotic episode I think? Hearing voices, talking to voices in my head. but, the scariest part was it fucked with my sense of time horribly. The order I did actions in was spliced and re-arranged. I knew what I did but I couldn't pinpoint if the cause happened before or after the effect if that makes sense. Anyone else have an experience like this
 
AM-2201 - Tolerance to Reverse Tolerance after Butylone Binge

I'm 24 and been a daily smoker since i was 16. when i rip a bong it's always the same .25 herb and .05 tobacco killed in one rip, i love that smack to the face it gives you. But after a while that smack would be diminished and I'd have to adjust my smoking schedule to once a day to really get the effect out of it that I wanted, but ideally I like to smoke 3 times a day, so AM-2201 was like a godsend to me. I got my hands on a large quantity and played around with AM-2201 for a while. I loved it, perhaps a little too much, I found that using the AM-2201 I could get to that headspace i wanted more often then just three times a day, which just was not possible with normal cannabis. I started "fast forwarding" through life which is what i call it when i wake up, smoke, fall asleep and repeat. With buds eventually i'd reach a point where i wasn't getting the high i wanted so I'd slow back to once a day but this shit was great, it could always get me there although i had to keep increasing the dosage. As time went on I developed a massive tolerance over time to the point where i would mix in 100 mg into a single bong rip after eating half a gram of the shit(mmm cookies). This led to some problems though because if someone took some of my shit to smoke or if there was enough AM-2201 residue in my slider they might OD on it After that I went on to just vaping the pure powder, since i could use less because i wasn't wasting any being burned until i needed like 5-6 dry bong packings(aproximately 200mg) per session. Then one night(well actually 2) I went on a massive butylone binge, about 2.5g oral spaced out and another 2.5g applied transdermally on lidocaine patches. Not sure how effective the patches were but definitely affected it because i was up the entire second night but hadn't taken any Butylone since like 6:00PM possibly even earlier, like 2:00PM. Throughout this binge i was, of course, sucking down the AM-2201 and also smoked a damiana/AM-2201 mix i had(2g/oz) to end the night since i killed the rest of my bud. I never smoke damiana blends but wanted the feeling of smoke in my lungs. The next day i went to smoke my AM-2201 just like usual and after one hit I was sent into hyperspace. I had never been so high before in my life and i even experienced my first panic attack and had to get a diazepam from my mom and curled up in bed with her, I was literally afraid that I had "done it" and reality was totally falling apart, my life was over, welcome to death, or really welcome to the realization that you are in hell. I've had very much the same experiences on lsd or other hallucinogens in high doses at my peak. Until I realize that if this is hell I might as well enjoy it the best I can and not worry about it. I can usually abort from this state by taking a bong rip which just snaps me back to reality( i think this is because I'm always high and my body's so used to it that being high is it's normal state. Despite this I continued to use AM-2201 multiple times daily however everytime i did it I'd experience the anxiety again not as bad as that first day but I also made sure to vape much smaller doses from that point on, still many times I had to abort the vape state with a regular bong rip and a few of these abort rips even had some AM-2201 in it which leads me to believe that I'm sending myself into a panic attack remembering that first experience. Sometimes I feel like I'm no longer myself and becoming someone else. Seeing my actions as the same actions that the people around me make just not as intense. Feels like I'm caught in a loop sometimes too, get massive deja vu(Oh No not again feeling). I also realized that i just wasn't getting sober I was literally permastoned and not just lazy and whatnot but like can't stand up straight floor moving like on a boat in rough water, I usually experience the floor moving since I suffer HPPD(permatryp) but more like a boat on mostly still water. It was fun, much like the after peak body effects of LSD with some slight visuals but distinctly cannabinoid not LSD like

I have some theories

1) It was caused by the butylone comedown causing anxiety and hence a panic attack. This experience then fueled the future experiences.

2) During my Butylone binge i was holding my bag of AM-2201 open and my hand started to shake and got AM-2201 everywhere i think i inhaled a good portion and it was all over my hand. So I may have a coating of AM-2201 in my lungs or possibly absorbed into my hand slowly being released from the fat or lungs into the body. Kinda like how when you eat brownies then smoke you get so much more toasted

3) I wasn't properly vaping the AM-2201 at first. To note, on the day the AM-2201 effected me so harshly, I tried a new way of laying the screen in the bong i used to push it down the female tube about half an inch in this time i barely put it in, just enough so it wasn't loose in the tube.

4) I hit the holy grail of drug addicts - Reverse Tolerance(possibly due to liver damage from the AM-2201 still containing some napthalene moiety or due to the AM-2201 itself)

5) The AM-2201 degraded into another more active chemical, or should i say potentiated since degrade connotes loss of potency

6)Everytime I closed the bag I'd squeeze out all the air and rolled it up perhaps I condensed the am- 2201 so more looked like less

Any other theories would be welcome
 
you just smoked way too much imo. similar things happened to people smoking normal weed. be happy, you didn't have a real breakdown and lower the dosage if you really want to do it again. cannabinoids are psychedelics after all...
 
Then why would it happen after I'd been messing around with this chem since May. Maybe i should have mentioned that in my post. I was smoking piles two weeks ago and barely anything. Now i put like 2 specks on and bam automatic trip out
 
I was going to say you got a different substance but it appears this is not the case.

For one instance, i could see accidently consuming enough to make smoking an experience more inline with oral consumption (this has happened to me when handling a bag of 35 grams of JWH-018)... but if this is happening a lot, I've got to go ahead and guess you were not vaping it quiet right, or you've adapted your method of consumption to better work with the chemical. I have not heard of this before, in fact, it's usually quiet the opposite. I remember having to measure out 10mg JWH-018, now I just dip cigs in a huge bag or dump some in a screened vape.
 
That's what I thought mostly. Assuming I was burning the product, therefore producing something else and not vaping it because the bong did fill up with a whitish gas but i just did an experiment using my old method of vaping with the screen further down and it still sent me off. Something else I've noticed is that there is a lot of powder residue in the bottle so maybe I'm just getting more from off the sides of the glass. Also any time i would let one of my friends take a hit of the pure chemical they'd get too high, so I started milking the bong for them and then tell them to take the tiniest inhale and wait 5 minutes before taking more. This may have caused much more residue to collect on the sides and now when i hit it a bunch of the AM-2201 comes off the sides. Maybe I should try washing it out with acetone(my favorite solvent BTW, not that anyone probably cares, lol)
 
Does anyone have any experience with the subjective potency of AM-2233?

Binding affinities are close to those of 2201 (1.8 at CB1, 2.2 at CB2 on 2233, vs 1.0 and 2.6 for 2201), so I'd expect it to be similar to AM-2201, maybe somewhat weaker - but using binding affinities to predict potency is hardly accurate. Anyone got any experience with it?

Is it qualitatively different from other cannabinoids? The structure is rather different, with the the iodobenzoyl group instead of the napthoyl of most cannabinoids, and the piperadine ring where most have the short-chain alkyl group.
 
People who get anxeity and paranoia from pot is it the same?

Hi guys I have a question im one of those people who used to love weed very much but probably over did it when i was younger and have not smoked it it in some years because it gives me anxeity and paranoia real bad paranoia and anxeity so basically i gave it up so i was wondering would the herbal incense make me react the same way do you guy who cant smoke mary jane any more cause of the bad effects have you tried any incences and did you freak out or was it like heaven reminding you of the sweet mary jane you cant dance with anymore???

thanks for any input
 
*I have anxiety disorder and get panic attacks* I smoke weed almost on a daily basis (usually twice, day and before bed) - when I was younger it ALWAYS gave me panic attacks and general anxiety. Here is what was 'key' for me: I discovered that HEY there are different strains! Different strains do different things.

Try researching strains, or Question: Have you tried various strains? (I prefer indicas - I find it calming in many ways. ALSO, stimulating enough to feel happy and focus... get things done) Perhaps there could be one/some out there PERFECT for you and your anxiety. :)

I really wouldn't recommend herbal incense as it isn't the same at all as cannabis varieties, and imo wouldn't be any less 'anxiety provoking'.
 
I find it so strange that back in the day I smoked weed everyday three times a day and loved every minute of it, looked forward to blazing and would be pissed if i was low on cash and couldn't toke up,but how could you smoke weed for years i believe what i was smoking was low grade and some times maybe a midgrade cannabis i never really came across potent stuff but what im saying how can you get high normally and love it and the next day it makes you miserable how does that happen i do realize when i was smoking heavy i hit terrible patch of my life at the time and just have believe that played a part of it after that it was never the same my doc diagnosed me with THC paranoia but what the hell right????have you ever heard of that???? hmmm some strange journey me and weed went through most of all my family tokes and it kills me to sit the sideline. they just say im a puss and cant handle the good mary jane but i don't know.


i would like to find diffrent strains and mix and match but i don't have those type of hook ups maybe one day when i get rich.

ah well weres the vodka!
 
The anxiety is all in your mind and is mainly psychosomatic IMO. I believe most people can get over this. I have terrible anxiety and for portions of time CB1 agonism would give me consistent anxiety and was not that great. I took a break but continued to acknowledge the fact it was me who had changed, not the noids. After awhile I gained comfort from being stoned again. Its happened a few times over the years.
 
its all in your mind man,
though i find weed belittles your ego,
in the sense that you may not be as confident,
so its not really your anxious, because i think weed helps that,
but it makes you scared of things that you usually would not be,
 
I kind of sort of believe its all in my mind because when this happened my life was miserable and me being young an immature not knowing things about the world just made the weed just send my mind for a loop i did allot of retarded things while high and they were really embarrassing so i think when i toke up that just brings them back and make me paranoid about it.cause i come from a long line of stoners even my grandpa blazed up god rest his soul. i mean back then i was hospitalized because i had a severe panic attack i thought the world was turning on me and the doc and my parents blamed weed it was weed to a certain extent but it was mostly me trying to face my demons and they won.Im a really quiet shy guy probably a little insecure and the not most confident in the world and i think when i blaze i just takes these issues and run with it and beat my self up and i work myself to an attack like people hate me they laugh at me they don't trust me.

so on to my next questions you guys say you can over come this how what are some of your techniques and did it take while to get back toking i heard beer helps when toking what should i do when panicking.

mods please don't delete or merge!!!!
 
bezel09- Im sorry I can not reply to your message. It says your inbox is full. If its not you may not be able to get my reply because you dont have the bluelighter status.
 
Can someone tell me what active chemical is in the california bud brand herbal incense the mods took my orginal inquiry down


thanks bezel
 
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