• N&PD Moderators: Skorpio | someguyontheinternet

MDPV - So how dangerous is it?

50-60 BPM isn't normal unless you do some sport and ~90 BPM is actually the heart rate you should have while sober and not under stress. You might also have arrhythmia, I'm like fainting when I get HR below 60.

I've never been fond of stimulants, especially those with 'amphetamine' core (cocaine beats anything in terms of euphoria and stimulation to do things; yet stimulants aren't my thing). MDPV is in no way superior to methamphetamine for me if I'm to discuss it anyway. Actually what causes MDPV to be addictive in a short manner of time is its short action. Besides in my experience its stimulant effects are more 'smooth' than e.g. methamphetamine's. But it in no way justifies MDPV or serves as a proof that it's safer to use. Side effects are clinically exactly the same. Just knowing it blocks NAT and DAT is enough to state it may be neurotoxic in certain circumstances.
 
I used to smoke MDPV daily for a month, lets says 30-50mg / day. I drank alot of water min 2L a day, take one or 2 hit every hours (2-4mg each), not to get fucked up just a mood lift and some energy.

I know some people that has problem with smoking like compulsive smoking every 5 minutes and got xtrem paranoia.

When smoked as I did I didnt get any side negative affect as oral redosing.I

It's nothing like crack when smoking the HCL until you convert to freebase, its become a light version of crack with shorter effetcs. Sleep was possible after 1-2h after the last hit.

After more than A month I didnt get much WD beside low energy for 2- 3 days but nothing big.

I prefer MDPV over fairly good Coke
 
My experience with MDPV

I have been using MDPV sporadically for the last year or so, and I must say its my favorite stimulant - I've tried Adderall, Cocaine, Crack, Ritalin, Focalin, Adderall XR, Vyvanse, and Meth. For me MDPV puts me in a great, energetic mood. The only complaint I have is that when I take higher doses (35-40mg) I get a tad bit jittery and the shakes sometimes.. PLEASE DO NOT TAKE THAT MUCH. I have been prescribed 60mg of Adderall per day for four years so my tolerance is ridiculously high. And yes, there is a cross tolerance, and MDPV tolerance ramps up faster than most. I myself have never experienced any paranoia or panic attacks, but i have gotten very jittery before.

My favorite MOA is smoking, either out of a light bulb or just in a pipe with a dash of tobacco in it. I usually smoke a bowl, snort a 2-3cm line, and pop 30mg orally. Literally puts me in heaven all night, gives off light tracers and some minor psychedelic effects, but when I want to go to sleep I pop about 5-6 10mg Valium or .75mg Halcion. The more MDPV you do, the more benzos you need available to come down on.

That being said, the one time I really was not happy with my experience was when i smoked a mdpv-laced bowl. For some reason it threw my thinking all out of wack and it felt like I was on 2C-E again. Weirdly, if you smoke during your peak, you will feel amazing. I have not tried MDPV in conjunction with anything but the above named substances, Xanax, Ambien, and alcohol (just one beer)

BEWARE: My gf (after I explicitly) told her not to decided to do 100mg in one night and developed into what I would say was around 60% total psychosis. She hallucinated that she saw me sexually abusing her dog, could not still, calm down, or do much but let her mind race. She was experiencing faster but slurred speech and a lack of motor control. This psychosis lasted for at least 3 days and was one of the worst weekends of my life because of how bad i felt not explaining what could happen. Also, another friend of mine took a rather large dose, 25mg or so, and experienced visual disturbances and he claims it almost felt like he was rolling.


Overall, this is a wonderful stimulant drug with many possible medical uses; however, it is extremely easy to take too much and have a nightmarish experience as many users have noted. Make sure you take the right dose, and NEVER more than you can handle. Hope this was informational for everyone, have fun and BE SAFE!!!

Ummm think thats all i was going to say anyone has any questions feel free to pm me or ask in thread if it would be beneficial. This is a great chemical if used properly!
 
50-60 BPM isn't normal unless you do some sport

Actually, this is normal for a fit human.

~90 BPM is actually the heart rate you should have while sober and not under stress.

People with a resting pulse this high tend to be very unhealthy. However, it sounds like you personally have fairly low blood pressure, coupled with a high pulse, which doesn't necessarily indicate poor cardiac health, as a high pulse coupled with high BP would.

ebola
 
My mdpv overdose (500mg over three days) gave me acute renal failure according to the hospital. I guess I forgot to drink enough fluids.
 
Snorting it consistently made gave me a speech impediment. Oral it seemed like a traditional stim. Smoking it was way too good and so it got flushed.
 
Snorting it consistently made gave me a speech impediment.

I have a theory that this widely reported stutter/speech impediment/unprecedented social retardedness is laargely a byproduct of the shortness of breath often experienced during peevee experimentation.

Even if a user is not immediately sent into or aware of the anxious state produced by an identifiable dose, the inevitable shortness of breath will often drive the user to unconsciously exhibit a number of self-induced symptoms of textbook anxiety before becoming aware of their emotional state.

Snorting is more likely to cause those symptoms because a user is often afflicted by the blinding fiendishness of peev. Oral administration lacks the awe-inspiring drive to redose following insufflation/intravenous admin/smoking which results in a lower overall dose. It is certainly possible to come to this state with oral admin but a longer, more drawn out process that not everyone undertakes.
 
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Nearly Pointless

Impressions from an experienced stim user?

Ive found it goes very well with jwh-018, and
light alcohol. Now the bad news, lets talk about
MDPV by itself.

Effect onset insufflated is a gradual buildup over
30 minutes. Speedy feeling similar to adderal or
other amphetamines, but way shorter duration.
Usually feels good for an hour, and only on the
first dose of the day. However, the comedown is
absolutely horrible, far worse than crack, meth or
adhd amphetamines. It feels similar to a crack
comedown x5. You have the urge to avoid people
or communication. Absolutely nasty feeling.
Considering there is no euphoria on it inhaled or
orally, the comedown is absolutely not worth
it. Also this made my heartbeat more irregular.
Im talking about 5 to 8 mg, same amount redosed 5 hrs later.
I can see people redosing just to avoid the comedown.
Advised to stay away.

2nd note: After only 3 days of use with normal sleep
every day, the comedown effect seems to intensify the
longer you use it. There has been discussion about
how to counteract the comedown to make it worthwhile,
and ive heard benzos and beta blockers mentioned. I honestly
wouldnt recommend mixing other substances with this,
considering just to use it without the bad comedown you
would be mixing chems or uppers/downers. If you need
more drugs to cope with this drug, its not worth it.
Adderrall, ritalin or other amphetamines give a much
more pleasant experience without the harsh comedown
 
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I am currently watching my friend on MDPV (insufflated, or snorted). Since im lazy im gonna use personal pronouns instead of names or pseudonyms. cause thats too much effort now. i will try to use correct grammar. don't know why though, maybe its all the love in my system, right now. We've been reading this thread cause both he and i were curious what effects it had. Erowid is only somewhat helpful. deep into the experience my friend wanted to describe what he did and took into account to have a blast. what follows is his pretty rambling advice, but it serves a purpose he says (the rambling serves a purpose).

He claims,
"Ive been reading this thread, and thinking about the concerns and effects this has had on people. maybe i can help in the future with some advice,
Mindset. A good state of mind prior to PV use is necessary as with almost any drug. A drug is a great way to let go and explore, either yourself and your beliefs or interact with others, if you don't feel like doing any of these then MDPV should not be put in you, well at that time. MDPV can allow you to interact with others and have a blast (earlier this evening), or it can open new eyes in your mind and reveal things you'll believe are life secrets. If you tend to be close minded to others thoughts and feelings, maybe try it alone and see if you desire human interaction like i did, twenty minutes after snorting, one line (5-6cm). Good Environment. This means both location and people. have good trusted friends or maybe a girlfriend with you, or nearby if you're testing it alone before you share yourself in peak awesomeness. People are great and provide some safeguards, while drugs are always risky, having a good friend with you to talk to can help you make better decisions on the drug.
Try a comfortable location, where you can see everyone, medium lighting adds a dreamlike quality to the interactions (if any! could be very intrapersonal experience just with others there) taking place. I realize i am rambling, if you are reading this then, you are either interested to see if something bad happens to me during my experience, or you actually care what i have to say. If the case is the latter, then you will most likely react well to MDPV (my opinion, everybody is different physiologically and psychologically and could have adverse affects to the drug, this person feels like the best way to learn about oneself is drugs. This is not however the only way, meditation, exercise, and sex (with a lover, casual not recommended, but still good, of course) can all have pretty much the same effect on you). Im not saying go out and purchase it and try it, i am merely trying to inform and answer questions those who might decide to, would like answered. Im open to answer any public comments (knowledge should be shared, one feeling from MDPV, significant reason why i wrote this) i don't want any of these horror stories to occur again, to anyone, ever. Im not sure how much i took, it was approx. 12mg or something, i forget now, and only measured out 10mg, plus approx 2mg for error, two lines, 6 hours apart, plus some focalin earlier (form of Adderol), also inssufflated, approx. 5-8mg, several hours before, maybe 3 or four hours prior to the MDPV being inssufflated. Also, smoked a couple bowls of mary, and took some hot knife hits, this i feel is irrelevant seeing as marijuana has almost no negative side effects, other than apathy and sleepiness, which the MDPV completely counteracts. I didn't plan how much i was going to do, since it wasn't mine i already had a limited supply. I would recommend if you do plan and do MDPV set a limit on the total amount everyone is going to do that night. You really don't need a lot, but you will want more, maybe its just the act of snorting, that;\/s really all im speaking with knowledge from. Overall i had an excellent experience with MDPV (still going) and as for seeing people and hearing sounds or other forms of psychosis, i don't think i took nearly enough for it happen, to me. Also, that risk of psychosis i read about multiple times, and few horror stories about what happens when psychosis hits, i will echo others when they say "limit the intake". Everything in moderation, i think this is true for drugs as well, since it is EVERYTHING in moderation i guess it already applies, but it doesn't hurt to say again. If you make it what you want, you can enjoy almost every aspect of life, with this Pharmo (i say Pharmo because i usually don't dabble in RX shit, or stuff with acronyms for really long scientific names). One last recommendation before i quit rambling, do something, whether it be alone or with a group, just talk, keep your ideas flowing, I thought this drug was similar to Ecstasy and Cocaine, however more so like X for me. Go mini golfing, or go to disneyland, these were all ideas of places where this would be fun. hell even regular golf would be fun to WATCH on this fun little white powder. I have never touched a needle, and never will i hope, to scary to be honest. Euphoria claimed by some is most definitely there when inssufflated, ingested orally, i have no clue, didn't try it, empty stomach n what not. If you had a bad experience on MDPV, i apologize, even though its no fault of my own, but that was not my experience at all, and i hope it never happens to you again ever. Just love everyone now."
"Lines for everyone!"

He wishes to be known, against some failed convincing, as the Insufflator General.

Take it or leave it, lol. He also says about halfway through he gave up on using correct punctuation or grammar, and he let his thoughts flow more freely like you should on this drug, apparently. I recommend a good soundtrack as an observer, because all night i got complaints about the music and not feeling it, make a couple cds, if you are planning on having a driver for in the car. or just make a playlist like 30 minutes after taking it like what happened what technically is last night, now. Enjoi, whatever you decide is best for you to do, i don't condone drug use...since they happen to be illegal, well some of em anyways. First post, not gonna be the last, by far best website i have found by chance.

-NewSOB
 
I would not recommend that anyone try this......personally I tried it for the first time this last weekend.....I had researched it all week, apparently I did not pay enough attention to all the negatives.

PROS- Cheap, gives you energy, talkative, maybe the legality of it

CONS (In order that they came) - speech impairment, slight uncoordination, paranoia, then became extremely paranoid, hearing voices, seeing things, then I had a toxic reaction, eyes starting watering, nose running clear liquid, constant foaming of mouth, throwing up, unable able to move, stand or walk, and feeling of paralyzation, blistering under eye lids. Not to mention, unable to sleep, even though last does was more than 20 hours ago. The sad thing is I was so F*<ked up, that I only realize now, that I had an extreme toxic reaction to this that could have killed me.
 
You guys are noting lots of weird side effects I've never had.

For me:
-Heart rate is elevated but only by about 5-10BPM.
-There is a milder comedown if used successively for several days, lasts a few hours or so the day after. There are no mood problems, just slowness and difficulty thinking.
-Mild appetite suppression.
-Less side effects than methylphenidate. Substitutes fine with it (I have ADHD).
-Suppresses sexual urges/desire.
-Not bad for concentration, but less effective than Concerta because I often forget to redose the MDPV.
-Duration is usually 4-5 hours, with residual stimulation last until 7 hours after.
-Active dosage is 1-4mg for me, sublingual. Taste is strange, slightly peppery (may be from pyrrolidine impurity) and very bitter.
-BP is normal.
-Less euphoria than methylphenidate.

Sounds like a run of the mill norepinephrine reuptake inhibitor to me -- from the stuff in the literature it's likely this one is more selective for NE.
 
It seems to be strongly related to whether you take freebase or salt in. The HCl salt is very dangerous due to its lower potency to CNS and higher toxicity to cardiovascular system, supposing it might be related to peripheral adrenergic effects, in contrast freebase is virtually no harm to peripheral nervous system, because of its higher potency to CNS might prevent users from overdose. HCl salt style is also far easily decomposed by heat, due to its property between vaporising point and decomposing point is too close to vaporise without decompose. Its toxicity is responsible to decompose at almost all in my opinion, supported from studies about serotonergic toxicity of MDMA -it is responsible to alpha-methyldopamine is neurotoxin. And, when take properly this substance is one of the most safe euphoriant in fact, from wide therapeutic value and non-neurotoxicity.
 
The HCl salt is very dangerous due to its lower potency to CNS and higher toxicity to cardiovascular system, supposing it might be related to peripheral adrenergic effects, in contrast freebase is virtually no harm to peripheral nervous system, because of its higher potency to CNS might prevent users from overdose.

Source?
 
Generally speaking, substances composed with ionised bonding have higher boiling point, this makes to need higher temperature to vaporise so increase risk to decompose, and moreover HCl salt is hydrophile, this makes more peripheral than central. No specified source in this substance but they are generally applied in pharmacodynamics.
 
Generally speaking, substances composed with ionised bonding have higher boiling point, this makes to need higher temperature to vaporise so increase risk to decompose

Maybe, but that only applies to that ROA.

moreover HCl salt is hydrophile, this makes more peripheral than central. No specified source in this substance but they are generally applied in pharmacodynamics.

pH of the blood and tissues is around 7.4. Whatever form you ingest it in, once it gets into the blood it will exist mostly in a protonated state (about 1000:1 protonated:freebase). So apart from affecting absorption, it makes no difference to kinetics or distribution.
 
Smoking MDPV gives an amazing euphoric rush for me, nasal administration too but no where near as strong. The slight burn feels great :). I'm deathly afraid of needles but I can only imagine the kind of pleasure it must give ;).

The most alarming thing about this substance is the constant urge to redose. I got a gram about 18 hours ago and have dosed many times (nasal 2-3mg, smoked 1-2mg weighed w/jewelers scale) and there's still the feeling that I want to do more. I can definitely see how this could get out of hand. I don't see how people can do 10 or 20mg doses right from the get go. However, my reaction to stimulants tends to be out of the ordinary.

This is an amazingly strong stimulant that even though you don't necessarily feel high you are indeed very (extremely?) high. Peripheral stimulation is at a minimum my outstretched hands shake no more than normal, pupils aren't effected, heart rate is at 87bpm (50-60bpm sober). Bruxism is very strong for me though but that is the same with any other stimulant I've tried including caffeine. There's an erotic aspect but no more than what comes with d-amp or meth (no tiny shrivelled pecker though).

This would be a wonder drug for work (I work in retail sales) where I'm forced to be 1000%, almost a caricature of myself, all day if only heavy (every hour with previously stated dosages) redosing wasn't such an appealing option.



Yeah, until your hiding in the cloths racks for fear of your customers stalking you, trying to kill or arrest you...JK, I thought about it for work too, but I afraid of harsh paranoia setting in.
 
MDPV is well known and used in Finland where it got banned extremely quickly because a lot of psychosis and death cases came up in relatively short period. I would steer the fuck away from the stuff because in Finland we have people who have died or are in permanent psychosis because of that stuff. Also the media in Finland have made a huge deal about this "new sex drug"

Friend of mine died from MDPV and it is considered a complete poison and shit drug here..please be very cautious when you use it and if possible just dont use that shit because it is poison..(at least here in Finland) We used to have a huge wave of MDPV hitting the streets when it was still legal and there were people hospitalized all the time and then they made it quickly illegal so if you are going to use please be extremely careful with this substance because it can kill you.
It is not like amphetamines etc. that are kinda safe to use sometimes this stuff can put you in psychosis from the first use. I dont want to sound like a dick but thats just my own experience watching friends using it.
BE EXTREMELY CAREFUL WITH MDPV!
 
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