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RCs MDMAI Experiences?

TooMuch2C-E

Greenlighter
Joined
Jan 8, 2011
Messages
17
So, for those who are unaware, MDMAI (Methylenedioxymethaminoindane) is an analogue of MDMA in which the alpha-methyl carbon is joined back to the benzene core, forming an indane system, granting it different pharmacological properties. I am a high school student with a rather advanced understanding of chemistry (for my age, anyhow). MDMAI acts as a non-neurotoxic serotonin releasing agent, and I'm heavily interested in researching it. I've read that it has a potency similar to MBDB. Has anyone around here actually tried this stuff, or any psychoactive aminoindane for that matter? If so, sharing your experience would be much appreciated.
 
Havn't seen legit MDMAI available yet. There were a few scammers claiming to sell it during the summer, but i don't there's been any actual MDMAI making the rounds.

There's a B&D thread in psychedelic drugs forum on MDAI, and for 5-IAI (which is crap, to make a long story short) as well. Both of those have been available for a while. The simple unsubstituted aminoindane, 2-AI, has been around for a while. It's a straight stimulant with an often reported analgesic effect as well, and lots of reports of weirdness and never gained much popularity. .
 
Their overall effects are rather disappointing, but I figure a sufficient amount of mdmai could equal mdma in terms of euphoria, though it'd take far greater amounts. Eh, I'm sure I'll be able to synthesize it in university and figure it out for myself.
 
Their overall effects are rather disappointing, but I figure a sufficient amount of mdmai could equal mdma in terms of euphoria, though it'd take far greater amounts. Eh, I'm sure I'll be able to synthesize it in university and figure it out for myself.

IIRC, MDMAI is just a pure serotonin releaser.

MDAI is a pure serotonin releaser. It is not MDMA-mimetic, at any dose. Addition of stimulants improves the overall effect (by increasing DA/NE levels). Certainly, MDAI + stimulants is greater than the sum of the parts. But, it's not MDMA-like. People have experienced worrisome symptoms (similar to SSRI withdrawal symptoms) after sessions of MDAI that are only a few times what people consider normal doses, which recommends against pushing the dose of pure serotonin releasers in hopes of getting mdma-like effects.

5-IAI also demonstrated clearly that triple releasing agents do not provide an MDMA-like experience.

There is some other activity of MDMA beyond DA/NE/5HT release. It acts directly on a number of receptors; i think 5HT1A-mediated oxytocin release might be the source of the 'magic' of mdma, which gives us hope that a selective 5HT1A agonist in combination with a non-neurotoxic triple release agent _might_ produce MDMA-like effects. But - that's conjecture - it could be something entirely different.

In any case, I have little hope than N-methylation will

Also, MDMAI is not an easy synth job. For at least a year after MDAI became available, most of the stuff on the market was 50% pure on a good day, due to synthesis impurities. The n-methyl analog is harder to make.
 
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It never occurred to me how difficult it could be to synthesize. And the information regarding it's disappointing effects is appreciated. I'm a manic depressant and don't respond well to serotonergic psychedelics, so with the knowledge that it isn't an MDMA-mimetic compound, I would assume that it leaves room for the excess of serotonin to go awry rather than carried in a pleasant direction in combination with hormones such as oxytocin. I was hoping for a means of returning to the world of chemical drugs without the cost of physical degredation. It seems 2C-E is the closest I can come to tolerating serotonergics, and based on how that stuff made my digestive system feel, I highly doubt 2C-E has a good safety profile. And yes, I know that as a manic depressant, serotonergics are the LAST thing I should be touching.
 
2C-E has a fine safety profile, as long as you measure doses properly and take it orally. The people who've been dying from it all snorted insanely large doses (hundreds of mg).


I would definitely steer clear of the MDAI-like drugs considering your condition - many have commented on an antidepressant effect from MDAI. So yeah, steer clear of that.

If you want to try psyches, try some of the other 2C's, or some gentle tryptamines like 4-HO-MET or 4-AcO-DMT (with great care) and see how they treat you.
 
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