I take 220mg of effexor xr. I used to take about 400 something. I'm still depressed at this low dose, so i assume not that much serotonin is being released? So would it be safe to take ecstasy? Should i stop taking it a day before or something. I also take buspar for anxiety, and lamictal for bipolar disorder. From what i've read on those two it shouldn't hurt. I want to try it before I go to a rave. I have been smoking recreationally for 4 years. I've used stimulants and opiates. I'm looking for something to rave with. I might try coke if I can't take x. Help/advice anyone?