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MDMA + Strattera (atomoxetine). Any known interactions?

cyberlexxx

Greenlighter
Joined
Nov 12, 2025
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3
Hey everyone. I was prescribed Strattera (atomoxetine) today to help with lack of motivation/suspected ADHD and depression stemming from said lack of motivation: this is after bupropion and sertraline didn't work for me. I have plans to party for NYE and there's going to be quite a few possibilities around me.
I can't find much research regarding this medication and its interactions with other drugs. Does anyone know if there's any conflicts with MDMA or cocaine? I know those two were very strict no-no's for the above medications, which is why I'm particularly interested in that info. I'll also have some K laying around but I don't believe that would have much of a reaction with Strattera.

Thanks for reading and appreciate any information 🩷
 
Last edited:
Hey everyone. I was prescribed Strattera (atomoxetine) today to help with lack of motivation/suspected ADHD and depression stemming from said lack of motivation: this is after bupropion and sertraline didn't work for me. I have plans to party for NYE and there's going to be quite a few possibilities around me.
I can't find much research regarding this medication and its interactions with other drugs. Does anyone know if there's any conflicts with MDMA or cocaine? I know those two were very strict no-no's for the above medications, which is why I'm particularly interested in that info. I'll also have some K laying around but I don't believe that would have much of a reaction with Strattera.

Thanks for reading and appreciate any information 🩷
Don't know that you still need this question answered, but someone might:

No, I am prescribed atomoxetine (80mg/day) and it's way to adrenergic and stimulating to have ATX and MDMA or Cocaine, or anything stimulating in my system at the same time. I've decided against even enjoying mushrooms at concerts because of that.
 
I have 2 days ago used the same idea MDMA + a stimulant (Adderall) and it went without concern but could be better. I saw Straterra mentioned and this is what prompted me to want to respond. I tried it for over a year and half and it did not seem to quell my mental wanderings. I have Guanfacine XR which was the same but also lowered my blood pressure. I am 7 years clear of cocaine and all of its constituents but definitely I am wanting more improvement. I latched onto this idea 2 years ago that somehow psychedelics might help and I began with mushrooms and I have never been able to feel comfortable on them and definitely was a recipe for issues with those. I just switched after many years back to Adderall from Vyvanse and so far I don't like the way it makes me feel. I think lots of folks on this board have a wealth of knowledge that I am trying to dig into. So I grabbed the material and course on MAPs and also decided that the material on Tripsit is very useful for me to know. I also have some LSD that I have so far taken 3 half doses over 3 months and each were very positive. I did feel some sort of perspective was gained in a positive way from my last MDMA journey 2 days ago, the problem is I have PTSD that in the last few years has become very isolating and I also routinely suffer from insomnia. If you read this I thank you and hope that I sleep soon. :)
 
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