MDMA + Phentermine

[enacer]

Has anyone taken Phentermine with MDMA? SWIM has a roll that only contains 1 part MDMA, they are very strong but the onset makes you very tired. Would mixing one roll with 1 low dose of phentermine be ok to keep you awake and functional? Thanks

 

[Fyasko.]

You've been a member since 2008 and you still say SWIM?

Phentermine works on the hypothalamus portion of the brain to stimulate the adrenal glands to release norepinephrine, a neurotransmitter or chemical messenger that signals a fight-or-flight response, reducing hunger. Phentermine works outside the brain as well to release epinephrine or adrenaline causing fat cells to break down stored fat, but the principal basis of efficacy is hunger-reduction. At clinically relevant doses, phentermine also releases serotonin and dopamine, but to a much lesser extent than that of norepinephrine

http://en.wikipedia.org/wiki/Phentermine

the extra adrenaline release probably wouldn't be too great for your heart
just to be safe, i wouldnt mix the 2.