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MDMA one day, MDA the next.

CrazyJordan

CrazyJordan

Bluelighter
Joined
Apr 29, 2010
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53
Hi, i am going to a 2-day dance festival this month and i was thinking of doing MDMA the first night, then MDA the second as i want to have both great nights without using mdma twice.

The reason is that i have read that MDMA + MDA do not have a cross-tolerance, here is a quote from PIHKAL
In one study, MDMA was consumed at 9:00 AM each day for almost a week (120 milligrams the first day and 160 milligrams each subsequent day) and by the fifth day there were no effects from the drug except for some mydriasis. And even this appeared to be lost on the sixth day. At this point of total tolerance, there was consumed (on day #7, at 9:00 AM) 120 milligrams of MDA and the response to it was substantially normal with proper chronology, teeth clench, and at most only a slight decrease in mental change. A complete holiday from any drug for another 6 days led to the reversal of this tolerance, in that 120 milligrams of MDMA had substantially the full expected effects. The fact that MDMA and MDA are not cross-tolerant strengthens the argument that they act in different ways, and at different sites in the brain.
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So is it safe to presume i would be fine? any input would be appreciated.
 
MDA and MDMA CERTAINLY have a cross tolerance, they may mainly work on different receptors, but they both release serotonin in heavy amounts. If you're low on serotonin, as you will be after taking MDMA, you won't roll very hard on MDA - guaranteed.


Why not just take both the same day? It's MUCH MUCH MUCH better that way, not to mention safer. Taking two serotonergic drugs days in a row, no matter what method of action they use, is not a smart idea, and will lead to a diminished experience the second time around.



Don't waste the MDA, just wait.
 
Do not wait 24 hours between this mix - Either take both (at reduced amounts the first day) or pick the substance you want to experience the first day and spend the second day in 'afterglow'. IF - your completely set on taking both substances two days in a row then what do you want from day two? If you want to jump about / dance like crazy then take the MDMA on day one / if however your looking for a more fucked up mental ride (not so physical) then Take the MDA on day one. If your looking for a fully fucked up weekend then I can only suggest taking half of both each nights - yeah the second night your going to be tired / wasted and the comedown will be from hell but !!!!
 
Heres another study regarding cross-tolerance,

The effects of (+-)-3,4-methylenedioxymethamphetamine (MDMA) (0.62-20.0 mg/kg), (+)-methamphetamine (MA) (0.62-5.0 mg/kg) and (+/-)-3,4-methylenedioxyamphetamine (MDA) (0.62-5.0 mg/kg) on milk intake in rats were determined before and during a period of repeated daily administration of MDMA. Experimental sessions consisted of 15-min access to a sweetened milk solution each day, 5 days a week. After initial determination of the effects of MDMA, MA and MDA on milk intake, rats were injected daily with either MDMA (2.5-5.0 mg/kg) or saline. Two groups of rats were injected with MDMA, one group 15 min before, and the other group 15 min after the milk-drinking sessions. Two more groups of rats were injected with saline, one group 15 min before, and the other group 15 min after the sessions. During this repeated administration period the effects of MDMA, MA and MDA (injected 15 min prior to the session) were redetermined. In rats that had been injected with MDMA on a daily basis either before or after the milk-drinking sessions, the dose-response function of MDMA was shifted to the right, indicating that tolerance had developed. Cross-tolerance to MA appeared to develop only in the group of rats that had been injected with MDMA on a daily basis before the milk-drinking sessions. Cross-tolerance to MDA did not develop in any of the 4 groups of rats.
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Yeah my reasoning for them on each days was the MDMA comedown will be more gentle than the MDA supposedly so i was going to take that the first day, bear in mind i dont even get a comedown from MDMA, but i think i might try something different the first day, then just mix them both on the last day for an extra special night.
 
No no no no noooo noohoooo no. MDA is highly serotogenic just like MDMA, same rules apply.
 
CrazyJordan said:
Heres another study regarding cross-tolerance,
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I've seen that study before, I'm PRETTY damn sure they're talking about cross tolerance between methamphetamine and MDA.


To say two highly serotonergic releasing drugs are not cross tolerant goes completely against any kind of common logic.... that's like saying amphetamine and methamphetamine don't have cross tolerance.
 
Folley said:
not to mention safer. Taking two serotonergic drugs days in a row, no matter what method of action they use, is not a smart idea, and will lead to a diminished experience the second time around.



Don't waste the MDA, just wait.
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The danger is not too bad, Folley :)
The early years were just mdma/mda combos.
I do not think much mda roams the world at this time.
Otherwise, you saw it back on ED maby ...?

My advice if you want freaking 2 days:
Take the first day less than the 2nd, and intermediate care that you supplement with vitamin and nuts. Macadamia nuts are very good to increase your serotonin level!

The best feeling remains 1 day party, but that is your choice ... :p

:D
 
I'd disagree. Rolling two days in a row is pretty damn neurotoxic. After you take MDMA, your serotonin levels are severely diminished, and they will need rest. If you try and shove out MORE serotonin after your already at those low levels, not only are you going to have done unnecessary damage, but you're probably going to feel like shit as well.



Although I have no idea what this means lol:


The early years were just mdma/mda combos.
I do not think much mda roams the world at this time.
Otherwise, you saw it back on ED maby ...?
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Yeah i think im just going to mix MDMA+MDA on the last night rather than both nightsi
 
done it before and its not too bad. just take your precautions with increased side effects the second day. try to eat and take your antioxidants and hydrate yourself CORRECTLY. that is all.
 
Folley said:
I'd disagree. Rolling two days in a row is pretty damn neurotoxic.
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Depending on how much you use.
You can also take everything literally folley :sus:
Not really relevant when you consider that, I estimate, 80% of users take more than the charge dose.
Two days drinking alcohol does more damage as a day MDMA and a day later MDA!

Believe me :)
 
IloveM said:
Two days drinking alcohol does more damage as a day MDMA and a day later MDA!

Believe me :)
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Um.... I wholeheartedly disagree with that.

Do you have a source? Because I think that's complete bull shit :\





People can drink for years on end and still live productive lives.... try taking MDMA for even a week, see what happens...






This is a harm reduction forum man!!!! Not a "I have done it and I'm fine" forum...
 
Contemplating doing MDMA the first day at a festival and MDA the second. Would I have a better time if I did MDMA + MDA on the first day and then tripped on the second? ( in terms of neurotoxicity/harm reduction blah blah ;) )
 
^ Sounds like a straight up waste of MDA. I think you would have a WAY better time just tripping the second day.. although personally, I would trip the first day and roll the second...


If you roll on MDA the day after you roll, you're not going to get much out of it.
 
Folley said:
^ Sounds like a straight up waste of MDA. I think you would have a WAY better time just tripping the second day.. although personally, I would trip the first day and roll the second...


If you roll on MDA the day after you roll, you're not going to get much out of it.
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Damn, not what I wanted to hear.
 
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