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MDMA and Phenibut Combination

Heroin Girl

Heroin Girl

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Not sure if this would be better suited to ED, but had a question about an upcoming roll....

I take 2g of phenibut daily and was wondering what effect it would have on MDMA. I generally take more phenibut with stimulants due to anxiety but had read a short thread on DF that made me think it would weaken the roll. Haven't been able to find much other info, so any help would be appreciated. :)
 
GHB, a gaba-b agonist like phenibut, dulls the roll of MDMA to some degree but at the same they enjoy great synergy together. I would guess the 'dulling' effect is due to gaba-agonism with GHB, and the synergy is due to GHB's complex pharmacology on several different receptors (eg. GHB receptor, serotonin, dopamine).

With phenibut, it doesn't have a mode of action that's as complex as GHB, and no stimulatory effect either. I would expect it to only dull the MDMA experience, without providing anything else. Much like combining any gaba-agonist with MDMA.
 
Ah that makes sense, thanks. Would you recommend avoiding it altogether on the day I roll?
 
Chromophobia said:
GHB, a gaba-b agonist like phenibut, dulls the roll of MDMA to some degree but at the same they enjoy great synergy together. I would guess the 'dulling' effect is due to gaba-agonism with GHB, and the synergy is due to GHB's complex pharmacology on several different receptors (eg. GHB receptor, serotonin, dopamine).

With phenibut, it doesn't have a mode of action that's as complex as GHB, and no stimulatory effect either. I would expect it to only dull the MDMA experience, without providing anything else. Much like combining any gaba-agonist with MDMA.
Click to expand...

Disagree with bits in bold.
 
^You've never used GHB to kill an amphetamine high?

Phenibut has as potent stimulatory effects as GHB?

Mind elaborating?
 
I find phenibut extremely stimulating..

And yeah I've tried using GBL to kill an amphetamine high but it never worked.. The only way it kills it would be overpowering it to put yourself in a self induced mini-coma.. Other than that they go great together.
 
baooozs said:
^You've never used GHB to kill an amphetamine high?

Phenibut has as potent stimulatory effects as GHB?

Mind elaborating?
Click to expand...

i would say phenibut is more potent stimulant wise than ghb though the stimulant effect doesn't kick in until the next day for me....this makes senes chemically also due to it having a phenethylamine core.
 
looking this up for a planned research project and this is the first place i landed. if there is anything else i may post it.

if i decide to follow through with said research i will most definitively update. long as im around....

💕
 
oh and i know its an old thread but if anyone has experience with this title can ya post, please?
thanks

still lookin.... 👀
 
no direct experience sorry.

but lots of experience with Mephedrone/coke/speed and GHB/GBL, and also lots with pregablin and mephedrone/speed/coke.

some parallels there.

I find these combo works incredibly well, especially mephedrone with GHB/GBL, by far the most euphoric feeling I get (though I don't do opiods and crack/meth)

my main concern with combining MDMA with anything is that you'd spoil the roll though, imho MDMA is something special and you may get limited uses of it in your life so I'm gonna take it on it's own and just enjoy it for what it is.

interested in your research though!
 
Phenibut is difficult to find. Ten years ago a company I worked for sold it, with many supplement cos selling it. Nows its way more regulated. In fact I paid btc for some last month and they refunded me bc they either ran out or coas are too old. (it goes bad and doesn't work in five years or so, from experience)

Heres a trip report https://www.bluelight.org/community...ho-mipt-5mg-experienced-fantasic-time.814280/

It went well for me, when this was done. That said phenibut would be better for the comedown, as mdma is stimulating and can keep one up if not taking in 6 hours or less upon awaking.
 
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