MDMA and CYP2D6 Inhibitors

[Genetic Freak]

Terbinafine is a CYP2D6 Inhibitor... Could its use prior to taking MDMA effect the action of MDMA..?

 

[Dmytry]

it will keep the mdma from being metabolized. meaning your roll may last longer, but the comedown will also be much worse, and will increase any neurotoxicity. there are a few threads about mdma and bzp, which also acts as a cytochrome inhibitor, dont remember which one

 

[Darksidesam]

so as dmytry basically says, it's not worth it.
Wait until your not not on the Terbinafine

 

[Genetic Freak]

so as dmytry basically says, it's not worth it.
Wait until your not not on the Terbinafine

Been on for the last 6 months so pissed off big time.... Unfortunately I'm stuck on the Terbinafine at least for the next couple of months until everything is cleared up....

Suppose I could always miss one days medication if a decent dance event was planned..?

Thanks for the reply's...!!!

 

[Dmytry]

Been on for the last 6 months so pissed off big time.... Unfortunately I'm stuck on the Terbinafine at least for the next couple of months until everything is cleared up....

Suppose I could always miss one days medication if a decent dance event was planned..?

Thanks for the reply's...!!!

missing one day may not help all that much depending on the half-life. i cant find a half-life value, all wiki says is "highly variable"