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MDMA and brain damage.

I just thought the ED section of bluelight would benefit from reading the article as there is amount of "Brain Damage" hysteria around this forum.
 
I'd like to see how this study was carried out. I do like these studies, but they are honestly just as skewed as the ones the Government puts out.




MDMA is not a COMPLTELY dangerous drug, but it is NOT safe either. These kind of studies are often conducted by giving users a SINGLE dose, and obviously that causes almost no damage in all cases. It's only long-term, constant abuse of the drug that leads to long lasting negative changes in the way the serotonin system works.


Also, it doesn't surprise me in the least that there are no cognitive changes from MDMA, no one here has said MDMA would make you stupid. If you could find a study saying there is absolutely no damage done to the 5-HT system after constant, or even a single, use I would be more impressed... but this study basically just tells us what most of us already know in a nice, concise and easy to read format.
 
Pretty interesting, maybe it doesn't cause 'damage' with a single dose. But the study didn't say how long after the dose they tested the patients etc. If they tested the patients for serotonin damage 1 year after a single dose , everything would have been cleared up by now.
I still firmly believe that it causes long term problems, meaning your brain will most likely come back to normal after a long time of abstinence but you may still go through long term negative affects. The threads on this site prove that, 'have i damaged my brain for ever' 'i don't feel normal' etc. You constantly see threads where people actually believe they fried their brain, long after they took the drug. So all in all, ecstasy most likely won't cause permanent damage. But it will cause long term problems for the user that will reverse itself over a good amount of time.
 
i think the term "brain damage" is not right. it might cause changes. "brain damage" implies that it's injuring your brain. altering brain chemistry and damaging brain chemistry would be different things. i think that maturity tempers the effects of the drug. there could be a parallel with romantic relationships. i believe that people are telling the truth about how they feel. sometimes i really feel like they're blaming a one time or week long experience for something deeper in their lives. i've kind of experienced both myself. some people can use frequently and even heavily and really feel better off for it. some people say that that one time has affected them for years. i read a story about a heavy heavy user. they said he had some short term memory loss. it seems reasonable but it could be possible that he would have tested that way regardless.
 
The study in question is here, in abstract. This looks like a typical case of the news media overhyping things a bit.

Mr. Halpern is right that studies on MDMA need to be carefully controlled, and his study is, I think, very well constructed. He successfully debunks the idea that regular (pure) MDMA use will turn you into an e-tard.

HOWEVER, Mr. Halpern does NOT make the claim that "no brain damage has occured," only that "no loss of cognitive function has occured." If you're planning to take MDMA, remember that cognitive function is not the brain's only function. Damaged serotonin receptors probably will not make it harder for you to do math, but they may make it harder for you to experience joy, love, happiness, etc.

This wonderful article on dancesafe details a possible mechanism by which MDMA can damage neurons.

I'm with Folley on this one:
Also, it doesn't surprise me in the least that there are no cognitive changes from MDMA, no one here has said MDMA would make you stupid. If you could find a study saying there is absolutely no damage done to the 5-HT system after constant, or even a single, use I would be more impressed... but this study basically just tells us what most of us already know in a nice, concise and easy to read format.
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