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Mdma And Anti-depressants - Mega Merged

any one have any input about Viagra and rolls - I can't climax while rolling anyway and without Viagra can't get maintain an erection...I guess that's what happens once you hit 40
 
zimed said:
Is not there any way in which I can simply and only flush it out of my brains' anatomy? I do not want to wait a month, and it feels like a long time to wait, but I feel, if I must....then I shall indeed.
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No. If you've been on paxil for five years, then you are likely to have to wait longer than a month.

As others have said, stopping paxil in order to take MDMA would be a very bad idea.

If you are ready to stop the paxil, then do so - in discussion with your doctor. Then, IF you are feeling normal and healthy after a few months, you can consider taking MDMA.

Also note what yellowfrog said. (S/he is a doctor).
 
Effxor XR vs MDMA ?

I'm currently taking 150MG of Effexor extended release tablets and was wondering if it interacts with MDMA or if I would be able to feel any of the MDMA because before taking the Effexor I was taking Cymbalta and couldn't feel a damn thing when I would take some molly. So I was just wondering if it would be the same thing with Effexor because they are so alike.
 
exactly the same thing. pills wont do anything apart from give you a real nasty comedown. been there done that many times unfortunately. just do some other drug if you must
 
mukant if you look in the Ecstasy Directory.......stickied at the top of the forum then you will find a heap of info regards effexor and mdma.
 
2 data points:

1. I was on 20 mg of citalopram per day. I could not convince my friend that the pile of MDMA in front of me would do nothing when insufflated. I railed it wincing at the waste. I received threshold effects of a stimulating nature.
2. I was on 15 mg of mirtazapine per day. MDMA felt exactly like it usually does for me. 2 trials, oral administration.

ebola
 
Quick question about snri's and mdma..

Hey all..done a fair bit of reading on the subject but am still a little curious how it will effect me..

Anyway, been on effexor(venlafaxine) for allmost 6 weeks(2 days off)..my doc said it would take about 6 weeks for the meds to start to take effect and i have noticed very vivid dreams over the past 2 weeks..

I have had a bit of gas in this time and it worked very well..try as i might i cannot find any for tonight but i can get a hold of some bikkies
If you're on a SNRI (Venlafaxine (Effexor)) you might be able roll, it seems to vary from person to person
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As i am only just getting to the point where the meds are starting to kick in is it very likely that i will be able to roll at all?

Thanks bluelighters :)

peace..walt..
 
well, reading the quote in your post, it appears that it varies from person to person. so if that quote rings true, you might roll, you might not roll.
 
I get the feeling you most likely won't. I think some people are able to roll on SSRIs as well if almost always requiring a larger dose. Seeing as Effexor also messed with Norepinephrine(NE) I'd think that'd really mess up MDMA, but I don't know much about NE and NE receptors.
 
The research you have aleady done is accurate.........you might, you might not.

I would very much appreciate if you could drop back in and let us know how it goes and what the experience was like.
 
Merging with the mega merged anti depressant and mdma thread.

Please post your experience there when/after you dose :)

And as others have said (and you posted yourself) the reading I have done on the subject matter suggests that some people are able to get the effects while others do no. I'm still not exactly sure why.

*Waits for 5-HT2 to jump in* :)
 
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anarky said:
Obviously the SSRI and MDMA combination has been done to death before, but has anyone tried stopping their SSRI, and used 5-htp for 3 weeks leading up to an event, and the week or so (even just the next day?) after then event. Then, start using the SSRI's again? Please inform me of possible outcomes and potential issues that may arise from this. Much thanks! :)
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I'd like to hear this, too.
 
branflakes said:
I'd like to hear this, too.
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5-htp use would be poinltess from what I understand. Perhaps even counterproductive. SSRI use does NOT deplete serotonin levels. It RAISES them down-regulating/desensitizing 5-HT receptors. 5-htp would further raise them and further down-regulate the 5-HT receptors.
 
Tianeptine isn't an SSRI, but it does impact serotonin. I guess it has some abuse and dependence associated, as well.

Anyone have any info about how it interacts with MDMA?
 
Ham-milton said:
Tianeptine isn't an SSRI, but it does impact serotonin. I guess it has some abuse and dependence associated, as well.

Anyone have any info about how it interacts with MDMA?
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There is ONE report of Tianeptine being used with MDMA and here it is:

fairnymph said:
I've been taking the setonergic antidepressant tianeptine for over a month now, at 12.5mg 3x/day. As of now, I have yet to experienced any direct effects of the medicine, either good or bad. It has not helped with my anxiety or my depression but I have NO side effects from it either. In the name of science (really!), I decided to see how rolling and tweaking would be on this medication.
Tianeptine and MDMA
This experiment was conducted almost exactly a month after I had started taking tianeptine at the dosage described above. The MDMA was PURE and ~130 mg. As a reference, I have had pills varying from about 100 mg to capsules that had 165 mg. Thus the dose this night was not exceptionally large for me.
The MDMA took a normal amount of time to kick in (~20 minutes, I had eaten a few hours earlier, but not much). Come up was particularily intense, without a doubt the most intense come up I have ever experienced (and in general, I don't much like coming up, I find it too overwhelming and erratic). At points I felt somewhat "confused" -- not clear headed as I normally feel on MDMA. This was the first time ever rolling that I felt I could not drive a car if necessary. I could walk and all that, but I was definitely slightly overwhelmed by the intensity of the high. Now, I don't particularily like feeling 'super fucked up', and had my roll been just a little stronger, I think it would have been uncomfortable.
I could definitely feel that the serotonergic aspects of the high were potentiated. The 'rushes' etc which IMO are mostly due to NE/DA effects were not intensified, but of average intensity. My euphoria however, as well as my emotional state, was extremely good, possibly better than even my first time rolling. I have had some issues rolling (my past 4 rolls or so), where I stress out and experience some anxiety, understandably dampening my mental state. I did NOT experience this during this roll, despite being amongst alot of strangers and in some weird/not-roll-inducive environments. My body high was by far and away the most intense body buzz I have ever experienced. Pleasantly so I might add.
The high lasted a normal amount of time, ~4 hours. Come down was normal/fine. During the days following the roll I felt as I normally do after a roll -- slight afterglow and no bad effects.
Tianeptine and Methamphetamine
This combo was even more interesting. The experiment was conducted a week after the MDMA experiment. ~70 mg were ingested orally (on an almost empty stomach) and about 1.5 hours later, ~15-20 mg were snorted. As a note, I had preloaded with massive amounts of vitamin C, magnesium and alpha lipoic acid, as I normally do.
As a further note, I had consumed 5 mg adderall on teusday of the previous week (the night of the meth-taking being a saturday), and of course the MDMA the week before, both of which probably have a *slight* effect on tolerance.
Now, this is more methamphetamine than I have ever taken at one time in my life, so I will factor that in. I have taken doses of 70-80 mg orally before, so I will be discussing primarily the part of the high prior to taking the 15 mg insufflated dose/supplement.
The high felt very much like rolling (as is typical with a high oral dose of meth), though with less euphoria/less body high. I was not expecting my medication to affect the meth high, so it quite surprised me that the experience felt even more like rolling than normal meth oral highs do. My mental state was EXCELLENT -- I was feeling very positive and motivated about my life. My 'head high' was definitely more euphoric than typically with meth. I would also say that I almost felt like the rushing/stimulating effects of the meth were weaker; but I feel this is because they were being overpowered by the increased serotonergic effects. Again, at points I felt very slightly 'overwhelmed/confused' which NEVER happens to me on meth -- I am always crystal clear/razor sharp. As I was feeling too much like I was 'rolling', and that had not been my intention for the night, I decided to snort some more meth (snorting usually has a very jittery/over-stimulating effect on me, which I hoped would counteract the rolling effect I was currently experiencing.). This boost of snorted meth did in fact help make the meth experience feel more methlike/less roll-like.
I might be back in a bit to add other details, but that's it for now.
Summary: Tianeptine potentiates (though not super strongly) the effects of amphetamines (including meth, MDMA).
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