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Mdma And Anti-depressants - Mega Merged

Ssre

Haven't read through this whole topic so not sure if this has been covered.
I'm taking an SSRE (i.e. serotonin reuptake enhancer). How would this affect a roll, if at all?
 
i take effexxor

and i still roll all the time

it just takes more for me to roll(which isnt really a good thing)

and the day after is shit

you dont know how bad it is unless you take anti depressants
 
See, it sucks because I have panic disorder and without medication, I'm pretty much fucked. But I'm gonna try soon to decrease from 100 mg Zoloft to 75 mg.
 
a SSRE does the exact opposite of a SSRI and to be honest, i'm not exactly sure if it would affect your roll or not.

here is some info i found. i don't have much more information than that, sorry. maybe someone with extensive drug knowledge could help you out.
 
OH MY GOD!

this explains so much!

Okay, I have been on Sertraline (Zoloft) for about three weeks now, and last saturday I took four rolls and got nothin'! I have mecke, marquis, and simon's reagents as well, and my pills tested fine.

I had two red hearts, a green rolex, and a yellow symbol of some sort (unknown...)

If I remember, I'll follow up when I can roll again. I'm on sertraline in the first place to combat methylphenidate comedowns... as suggested by my doctor.

Hope this doesn't take too long!
 
I was on citalopram (Celexa) 10-20 mg a day for about 3 weeks, until I realized it was useless and stopped. I didn't have any withdrawal effects, but I have yet to roll very hard. It could be weak pills; I don't know anyone else who has used the same batches so I can't get a second opinion. The most recent time I also ate some fairly strong acid, and I THINK I was rolling but it was kind of hard to tell. :o I'm a bit concerned the stuff might have screwed with my enjoyability of MDMA for good. I'm going to try again soon; by my calculations I should have no more than .005 µg of the crap left in me, and I have some capsules from a reportedly good batch, so I should be able to see how it goes without being under the influence of SSRI anymore. Needless to say I would advise against taking SSRIs to anyone who wants to continue enjoying e. if you're getting depressed and you use on a regular basis, maybe just consider taking a break. ;)
 
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MDMA causes your brain to dump a load of seratonin at one time.
SSRIs regulate the flow of seratonin in your brain. If you are taking an SSRI, it is impossible for MDMA to do its job, as your seratonin is already being regulated by the SSRI. The whole point of the SSRI is to maintain a constant level of seratonin.....which is the exact opposite of what MDMA is meant to do.
You may get very mild effects from MDMA if you are on an SSRI, but you will never get the full effect because the two drugs are working against one another.
Seratonin is your mood regulator. Its what makes you "happy". If you are suffering from depression, coming off your meds and then taking MDMA is one of the worst things you can do. As I already stated, MDMA causes a large amount of your seratonin to be released at once. When you are finished rolling, you are left with a huge seratonin deficit. It takes your body several days to replenish that seratonin and during those several days, your depression will be aggravated. Most people, even those who don't suffer from depression, experience a "blue" period, usually two and three days post roll.
As for 5-HTP: It is a pre-cursor to seratonin that your body will readily accept. Thus, tricking your brain into producing an excess of seratonin in a much shorter period of time than your brain would do on its own. Taking 5-HTP daily is highly recommended to those who roll and, as a side note, 5-HTP has also been shown to help all people suffering from depression, not just those who roll... negating the need for an SSRI.
Hope that answers all your questions on SSRIs and MDMA. If not, please ask away!!!
 
Another side note, about 5-HTP. Some people, realizing its effects on the replenishment of seratonin, try to take more than one pill a day, attempting to hurry the benefits along. I'm not sure as to whether that works or not, however I am sure that taking more than one dose of 5-HTP daily can cause you to have very vivid and disturbing/scary dreams.
 
^^^true last night i had a dream i went shroomin wasn't scary kinda kool IMO took 200 mg of 5-htp
 
Hey I know the relationship between Prozac and MDMA is not well known but generally, what is the consensus of taking MDMA after being on Prozac for about a year. I mean, approx, how long should somebody stop taking Prozac for to be able to rolllllll nice on MDMA or MDA.

Thankss.
 
MDMA, SSRI and come downs

here is an interesting question - if you are on anti depressants (SSRIs - luvox in my case) and you take some MDMA and don't roll do you still have awful side effects or comedown the next day? I am wondering this because this happened to me and i want to know whether this happened because of my MDMA or whether it was to do with the pills. It would be awesome if someone could shed some light on this.
 
Freedom: hard to tell. I'd suggest waiting a couple of months (you also want to make sure that your body/brain has adjusted to being off prozac, and that you're not feeling depressed without it).

dachaffa: not sure. As I understand it, SSRI's would only block the effect that MDMA has on serotonin. So you wouldn't get the loved-up, empathic feeling, but you might still get some energy from dopamine release. And you'd then presumably get a comedown from that. Or, maybe your pills weren't MDMA.
 
they are mdma well some of it is i have tested them. here is another question taking MDMA when on SSRI - because you dont roll does that effect your tolerance levels the same as if you werent>?
 
That's weird.. I never knew AET had effects more similar to entactogens than tryptamines..
 
please read

hey all,
im on my 6th pill of 10mg of lexapro. im gonna take e this weekend. will it not work. should i not take it for thursday friday and sat? please help. i do wanna roll. is it too late?
Adam
 
[email protected] said:
hey all,
im on my 6th pill of 10mg of lexapro. im gonna take e this weekend. will it not work. should i not take it for thursday friday and sat? please help. i do wanna roll. is it too late?
Adam
Click to expand...


1. No it probably wont work.
2. You shouldnt just stop taking anti depressants.........its not like a headache pill.
3. E has been known to exacerbate depression hence for someone that already has problems.......E is not a good idea.

4. I suggest you wait until you are finished your course of lexapro..
 
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