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Mdma And Anti-depressants - Mega Merged

Nortriptyline hydrochloride is not a monoamine oxidase inhibitor. It inhibits the activity of such diverse agents as histamine, 5-hydroxytryptamine, and acetylcholine. It increases the pressor effect of norepinephrine but blocks the pressor response of phenethylamine. Studies suggest that Nortriptyline hydrochloride interferes with the transport, release, and storage of catecholamines. Operant conditioning techniques in rats and pigeons suggest that Nortriptyline hydrochloride has a combination of stimulant and depressant properties. So it doesn't interfer with serotonine.
 
I know of no widely and currently prescribed "antidepressant" on the market that is worth the time, money, effort, and brain cells used to procure and support its daily use.

Simply put, they suck--except for Wellbutrin (buproprion) which is similar to but not the same as a caffeine rush and Deseryl (trazodone) which is a pleasant sedative.

The whole theory behind this strange phenomenom presupposes that "depression" is a neurochemical, chronic, incurable physical process that can and should be fixed with a happy, but not TOO happy, pill--instead of the condition of the mind/body/and soul that it actually is.
 
ok, back to me insufflating that last roll i had (sorry, i haven't been online in a couple days, and...well u'll see...):
so i insufflated that last roll i had just to see if anything would happen...well within 15 minutes i felt the effects...within an hour i was rolling NUTS...BUT.....WITHOUT the euphoria...i experienced all the effects of MDMA aside from the euphoria...very weird...i even "shot the salad" for over an hour (TEARING IT UP on my new skates in dreamland,hahahhaha)....i couldn't even bring myself to the computer to tell u guys what happened...any idea what happened here? was it the wellbutrin? i wanna add one thing that i forgot to mention in my original post....i had been taking 100mg 5-htp daily for over a month (then when that bottle ran out i stopped)...maybe that had an effect...i dunno
 
ir eally can't give you an insight on what might have happened but some people report that even when on wellbutrin, they can still feel some of the MDMA effects; this may be the case with you.

i don't know what "shot the salad" is and i'm not sure i want to.

are you completely off your meds now?
 
^ lmao. i thought "shooting the salad" was an accepted term on this site. what i meant by that is doing shit like thinking i'm out skating, meanwhile i'm really just sitting on my bed. most people report "dreaming" they are at work while "shooting the salad." i dont know an official term for this phenomenom, but its quite common among ecstacy users.

i haven't been on wellbutrin for about a month. and about 2 months since i've taken 5-htp.
 
^ You've never been rolling really hard and then thought u were somewhere else than where u actually where? example:

a friend of mine, who worked at subway, occasionally would ask "and what would you like on your sandwich?" while we were rolling. id be like "what are you talking about?" and he'd say "Oh, i thought i was at work."

its actually my favorite part of rolling. pure brain scramble. i'd be surprised if you've never experienced this before. almost every roller i know has in one way or another.

oh and i dont think the 5-htp did anything. i insufflated that last pill only 3 days after taking the first 4 (and feeling NOTHING.) and i had stopped taking the 5-htp a month before stopping the wellbutrin.
 
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^ I'm pretty sure its just a term made up of two words that really make no sense together. In this state of mind one commonly says things that make no sense. I can't wait to have my next in depth conversation about rakes (LMFAO...props to the OG rake poster, whoever that was.)

Anyways, two nights ago I tried rolling again (2+ weeks after insufflating that last pill.) Three oral, half insufflated and half parachuted. Once again: unsuccessful. Although I was a little bit more out there this time. There was definetely some MDMA relaxation, but no 'blowing up' still. I'm sticking to my original hypothesis that this inability to roll is not the result of bunk pills, but of my Wellbutrin use. I don't know what Wellbutrin actually does for people, but in my experience, the only noticable effect is the inability to experience MDMA in its entirety. Hopefully that shit will be out of my system completely by my next attempt.
 
The reason you won't get as much of a trip relates to the reason why withdrawal from SSRI's is agony... your brain habituates to the higher levels of serotonin over time, so the meds increase the basic threshold around which relative increases or decreases in serotonin are neurochemically significant. My guess is that raised threshold swallows up most of the increase produced by the MDMA, so you never get that 'tsunami' feeling. I've experienced the same thing on two different mood meds -- relaxed feeling but not much else.
 
My withdrawal from SSRIs was not intense (Zoloft). I am back on them at 125mg for anxiety.

I always knew about the no rolling and SSRI thing so I just assumed it to be true. Anyways on NYE I got some pure MDMA after nothing for a about 1.5 years and it definetely hit me hard. I had to take more than normally would have before but I was definetely feeling it quite a bit (9+ year experienced user before the self imposed break, I know what MDMA feels like ;)). Definetely not something I plan on doing often if ever again, but it was pretty interesting that it worked.
 
Very happy to find this thread. Has explained a complete intolerance to roll at all, Venlafexine is the one stopping my fun. 10+ created an urge to smoke a few cigarettes more then usual.
 
GreenBarts said:
zoloft for aniexty? get off the perscription drugs, the whole industry is a joke. may god have mercy on your mind.

Higher dosages have been effective for anxiety. Worked to help stabilize me while I went through CBT.
 
question bout bipolar meds???

ive recently been diagnosed with having a little league version of bipolar disorder. My therapist told me to research the two drugs he possibly wants to put me on one of them is Lamotrigine(Lamictal) and Lithium...I wanna know if i can do any e or mdma with either or is it just simply a no? I havent been able to find any answers only with Lamictal it says to avoid alcohol and illegal drugs.
Lithium seems to be really iffy it has so many be carefuls not to take this sorta thing (caffeine etc..)

I have been on antidepressants b4 when i thought i had just clinical depression-effexor and cipralex were two of them. i had no problems doing e on cipralex i only had problems with alcohol where id get manic
Can anyone answer my question?
 
according to drugs.com it is not known how lamictal works on the brain so i can't really tell you if it would block your roll or not.

lithium and MDMA

i know it's not what you want to hear but i'm going to advise you to not take MDMA or any other drugs since you have been diagnosed with a form of bi-polar disorder. if your dr. is trying to prescribe you lithium, you should definitely stay away as it's a drug that i have only seen being given to severe manic depressives.

research both of the meds so you know what you're taking and figure out which you think would be best for you. stick to it and after your dr. has noticed improvement, you may want to discuss getting off the meds. consider using MDMA only after your dr. has given the ok, you wouldn't want to make the condition worse and it CAN happen.
 
Thankyou for replying its actually what i suspected but at least i know to stay away from mdma if start this therapy.
 
if you need treatment, don't postpone it or not go on it at all just to use MDMA. you seem like an intelligent person but i just wanted to warn you that MDMA has been known to cause depression and has been known to make a previous condition worse.
 
hi

hey, i have a major problem.

about to begin use of "Lovan" SSRI's. active ingedient is ____. well, to the point. i have a major rav coming up in 2 weeks and i have lined up 2 yellow diamonds which i am going to do anything to get the best roll i can because they have a good reputation and i aint gonna waste em'.

will it be worth the risk to take the SSRI's now and start them. or can i begin and still geta good roll, i guess u cant estimate this kinda thing. just want another opinion.

oh and does SSRI's affect other drugs like, speed 'base', ice (shab's) or alcohol/weed?

thanks heaps
 
lovan is fluoxetine, the same thing as prozac.

I'm on an antidrepressant, can I roll? Chances are, no. If you're on an SSRI (e.g. Citalopram (Celexa), Escitalopram (Lexapro), Fluoxetine (Prozac), Fluvoxamine (Luvox), Paroxetine (Paxil) and Sertraline (Zoloft)) if you take MDMA, you will not feel much of anything.

i think if you start taking it now it probably won't have much of an effect on your roll but there is a chance that it might. SSRIs usually take about 2-4 weeks to start working properly. if you are supposed to be starting an anti-depressant, you are being told to do so for a reason. please think about the costs/benefits of using MDMA if you are depressed.

 
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