MDMA after an amphetamine binge

[guy1234]

also what would happen if you took MDMA after an amphetamine binge? or during the end? would the dopaminergic part of the MDMA high not happen leaving you with just the mellow seratonin high? or would the whole thing just fuck up and the MD not work at all

 

[ugly]

I finished three days of straight up speeding day and night the day before yesterday. Yesterday I slept. Today I took 3 e tabs and barely rolled at all. I'm not saying one thing caused the other, just that I'm not feeling it like I should be. They pills were legit. Others dug 'em.

 

[fryingsquirrel]

MDMA is an amphetamine after all, some level of cross tolerance is to be expected.

 

[Fornax55]

i'd imagine MDMA would still be fairly effective, seeing as MDMA causes a rush of serotonin whereas the meth would have mostly depleted only your dopamine reserves...

 

[Keif' Richards]

There's definitely cross-tolerance. I wouldn't take E the day after using speed, let alone after a binge.

 

[Fornax55]

i wouldn't take ecstasy tabs, but that's likely because they're loaded with just enough meth to prolong the comedown... pure MDMA, on the other hand.. :D

 

[guy1234]

yes we are talking crystal molly here of very reasonable quality

 

[rickolasnice]

i'd imagine MDMA would still be fairly effective, seeing as MDMA causes a rush of serotonin whereas the meth would have mostly depleted only your dopamine reserves...

Alot of MDMA's effects are alot more dopamine based than people seem to think.

 

[guy1234]

hmm so if we said a normal MDMA high = 100, and after a binge of amphetamine it = 50, how much would it be increased by, by taking say 1000mg of tyrosine between the two?

 

[Fornax55]

Alot of MDMA's effects are alot more dopamine based than people seem to think.

i hoped it would be like that... but being on SSRI's and having my serotonin production largely inhibited, when i took a good dose of MDMA i didn't feel anything except a weird fuzzy pressure inside my head

 

[lazydullard]

hmm so if we said a normal MDMA high = 100, and after a binge of amphetamine it = 50, how much would it be increased by, by taking say 1000mg of tyrosine between the two?

If you took the tyrosine shortly before the mdma, I'd say it would go to 60, but only for like 2 hours, then the crash would be worse, and all the side effects would be worse.

I took tyrosine during an amphetamine binge.. It was two hours since my last dose, and I was already a bit too far gone, but the tyrosine boosted the high to a very bad place for 2 hours.

Tyrosine just isn't worth it with amphetamines.

In regards to the thread title... if the amphetamine is still getting you high, the mdma should get you high still... but are you looking for a high or for magic?

 

[guy1234]

i'm not very well aquainted with drugs chemistry. so i make some assumptions, (please correct me):

that the MDMA high is mainly causes by increasing the concentration of ''happy chemicals'' in your brain or/and by increasing the production of these chemicals.

that the main ''happy chemicals'' that contribute to the high of MDMA are dopamine and serotonin and if either of these is unavailable, the high becomes fairly pointless as without serotonin it is basically a speedy cracked out high and without the dopamine a serotonin high sucks.

that tyrosine speeds up the replenishment of dopamine in the brain.

ok so based on these assumptions, already knowing that amphetamines work mainly on dopamine, i know that after a binge on amphetamine, my dopamine levels will be very low. however i plan on taking MDMA very shortly afterwards (within 12 hours). because apparently a purely serotonergic high is shit (newly learned) i was wondering if taking tyrosine would help to replenish enough dopamine to make my MDMA high if not amazingggg, then good.

before you say it, no i can't wait until a later date to do the MDMA, for reasons i wont share

i will be doing the MDMA regardless of how many people say ''just dont bother'' so all i want are suggestions on how to improve the situation.
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as an afterthough, if i am still getting moderately high from my amphetamine, and i continue using it DURING my MDMA high in much smaller doses, what will this do?i guess my current state shows that i do have SOME dopamine to drag on.