Yeah should be safe. Tramadol is rumoured to have SSRI properties though and I think I have experienced this once. Took (a big dose of) tramadol the day before a roll and got stuck in that anxious comeup phase for 4 hours during the roll, it was like something was blocking the full effects, I never properly came up. And the pills that was with were tested and high dose judging from previous experiences. I would avoid rolling the day after