(+)-Matrine - a natural opioid

[Limpet_Chicken]

Sophora? I'd be careful to get the right species.

Cytisine is present in S.Secundiflora for one.

 

[LuxEtVeritas]

both matrine and the aforementioned extract I have a goos feeling would be well disappointing...move along

 

[Tsukasa]

Activation of the κ-opioid receptor appears to antagonize many of the effects of the μ opioid receptor.[17]

 

[mitragyna]

That's a pretty big violation man, that's a direct link to a vendor, though cloaked in an image.

Shit, my bad. I had no idea there was link on there. Whoooopsie

 

[mitragyna]

Activation of the κ-opioid receptor appears to antagonize many of the effects of the μ opioid receptor.[17]

Yup. That study is here.

 

[(zonk)]

I always thought that as pretty obvious IMO. Salvia is a physacly painfull torture drug for me, I would ONLY consider ever doing it again if i was on a strong opiate to block the pain. But then again, opiates make me feel like shit so it will probably never happen

 

[nuke]

I hate mu-opioid agonists but liked salvia. I am not sure I'd enjoy it even more if it lasted longer, though. Salvia had antidepressant effects on me after the acute phase (though at some points during the acute phase I felt physically uncomfortable).

 

[mitragyna]

I hate mu-opioid agonists but liked salvia. I am not sure I'd enjoy it even more if it lasted longer, though. Salvia had antidepressant effects on me after the acute phase (though at some points during the acute phase I felt physically uncomfortable).

The K-Opiate affinity of Buprenorphine must be why in some very depressed people, it's the only thing that can successfully lift their mood. For example, me