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LSD - receptor mutation ?

DylanG204

Bluelighter
Joined
Jun 7, 2012
Messages
123
After years of searching for lsd , i found a sheet with the god shevia on it
definatley an ergoline , not much visuals , excellent body high and had a great time everytime .
visuals did not increase with more dose. I think this was MLD-52 , or some kind of analouge as myu dealer was into 2ci at the time

Finally i found somebody with what i think is genuine LSD-25. i estimate it too have about 90-120 ugs

at first 2 or 3 tabs is enough for a strong trip , no hangover the next day no mental foggieness or that drained feeling , still felt good and mild visuals from the night before
( not knowing too much about tolerance and general and how out of controll it can get ) i dose the next day , this is the most amazing chemical ever , thinking weird thought loops
sometimes speaking complete gibberish , squares and spirals , things are swirling , colors are great , FOOD AND SEX ARE AMAZING .

after a 2 month love affair with me my girlfriend and lsd , eventually taking up to a 10 strip at once , my tolerance was though the roof . i feel like i am wasing this precious chemical.
i used too have a great time from 3-5 tabs now im eating over 20 in one night , eventually it looses the weird headspace and the trip is olny visual !!! Sometimes i cannot stand up for too long on high doses of lsd without getting nautous , when i sit down i feel better , i cannot stand longer than 5 minutes without the nausea coming on , i contribute this too lsd toxicity . I DONOT get any introspection , no weird thoughts, it is pureley a visual high with no mental effects (besides slightley impared thinking) increase in dose would olny engance the visuals .


it has been over 2 months now , when i eat lsd i can tell my tolerance has went down but olny very slightley , it is still rediculos
when i eat shrooms now the high resembles lsd alot , i have no revelations or amazing thoughts , i have waited several months and i feel as if my brain is permanantley changed too host all of the acess lsd i was expposing myself too .

If i had known the effects of abusing lsd i would have respected this way more than i already have , lsd is an amazing chemical but like everything you need too have moderation , i have learned this the hard way .


has anybody elce lost the mental effects from phycadelics or shrooms , and does this come back after some time? it has almost been 6 months now and not much of a difference .
 
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Yes it comes back. Don't take anything for 3 months then try again. If that doesn't work don't take anything for 6 months.
 
Take a break for longer....eat fruit and vegies, exercise regularly and give it time and you will be back
 
LSD doesn't really give me a lot of introspection anymore either. I never used it to quite the extent you have, but at times it would seem close.

I hadn't had any in a few months and recently just ate 3 or 4 drops of liquid and licked the dropper, I tripped balls. It was still mostly visual and barley any introspection. Mushrooms are full of introspection though but I have way less experiences with them.
 
thats good too hear , its been 6 months and more , and i still get no introspection from mushrooms , i feel as if my brain is permanentley changed
abuse and high doeses of lsd does exactley that .

has anybody elce expereinced lsd toxicity or receptor mutation>?
 
Maybe you have just gotten kind of a permanent or very longlived tolerance to LSD and possibly other 5HT-2a psychedelics. I'm sure it will neutralize at some point, but could be years. I definately doesn't think your receptors are mutated.. Maybe somewhat overstimulated/lacking sensitivity

This is only theory based on some facts about tolerance-building and my own ideas.

Maybe it could allso be your expectations for the trip(s)? Try meditating maybe.

I, my self, is generally kind of a hardhead when speaking psychedelics, but no rule without an exception. Even though I've eaten up to +25g. dried p. cubensis over night, 1,2 or 1,3g of the exact same growkits raped my mind. Recently I extracted n,n-DMT freebase and I must admit I'm no hardhead when it comes to DMT. Could be an alternative for you maybe.

You aren't on any medication, are you?

//blazR
 
Receptors do not "mutate".

I think what you have is similar to the "loss of magic" from MDMA - you've just done psychedelics enough that the novelty has been lost, and combined with acute tolerance it makes the experience seem underwhelming.

You could try waiting a good 6-8 months and taking a fairly large dose of psychedelic in a ritualized setting. If you still don't get the results you want it may be a sign to "hang up the phone".
 
I don't think you are experiencing either toxicity or receptor "mutation," just down regulation and psychological tolerance. LSD has a broad receptor profile and if you're taking a lot you're probably getting substantial 5HT3 agonism/nausea/anxiety. Switching to a different psychedelic won't change anything, it would just prolong the amount of time you need to wait before things reset themselves naturally.
 
thanks for the info , have any of you thought about reverse agonist pescriptions ?
is there a natural source for this?
 
The receptor involved in the hallucinogenic effects of LSD et cetera is downregulated by inverse agonists too, there are no drugs that can fix your problem.
 
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