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LSD and MDMA Cross-Tolerance

ErgicMergic

ErgicMergic

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I'm planning on taking LSD (0.5 tab - 1.5 tab) at a 2-day rave this weekend on one of the days, and 2-3 good Ecstasy pills (pokeballs) on the next. It will be my second real trip, third time using LSD, and my first roll. :)

Will there be serotonin cross-tolerance with the two drugs? I know MDMA releases serotonin, while LSD is an agonist on pretty much all the 5-HT receptors. I'll probably do the LSD first, then the E the next day. Any problems? Tips? I really want the best roll of my life on Saturday, so I'm just trying to be prepared.

Thanks!
 
^^^^ this. if you have a comedown from the pokeballs your less likely to have a good trip. do the l first :)
 
Would doing LSD on day 1 affect the intensity of my roll on day 2? Should I just stick to a tab/half-tab instead of 1.5-2 tabs? Or can you trip hard one day and still roll balls the next day?

After taking about 3 hits of acid, I felt pretty weird the next day, until 48 hrs after dropping the acid (not bad, just weird, like I was still half-tripping, great for introspective thoughts).
 
it will affect your roll but not much. although they both deal with seratonin, LSD doesnt flood the synapses like MDMA. works in a completely different way. however, there is a good chance you will be tired and your brain a little overworked, which would affect the roll, but if you get good sleep and food after your trip, you should be fine
 
rincewindrocks said:
it will affect your roll but not much. although they both deal with seratonin, LSD doesnt flood the synapses like MDMA. works in a completely different way. however, there is a good chance you will be tired and your brain a little overworked, which would affect the roll, but if you get good sleep and food after your trip, you should be fine
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^this.
i also read a study on how LSD downregulates 5HT2 receptors so that could be a problem too.
I'm planning on taking LSD (0.5 tab - 1.5 tab) at a 2-day rave this weekend on one of the days, and 2-3 good Ecstasy pills (pokeballs) on the next. It will be my second real trip, third time using LSD, and my first roll.
Click to expand...

i really hope you're talking about some OG pokeballs you had saved.
because all the pokeballs out now are complete crap...and dont deserve to be called "ecstasy pills":p
 
Fyasko. said:
^this.
i also read a study on how LSD downregulates 5HT2 receptors so that could be a problem too.


i really hope you're talking about some OG pokeballs you had saved.
because all the pokeballs out now are complete crap...and dont deserve to be called "ecstasy pills":p
Click to expand...

The HHs, Ferraris, nikes and Thinkers were OK, MDMA, meth and caffeine. They were still shit though, legit Pokes are dead...

I would personally just pick one day to candy flip, but you will be fine. I would take the LSD early though, and make sure you get plenty of rest for the next day
 
Yes definitely do the LSD first. I have done this for a few festivals ... LSD the first night, M the second night. Would definitely recommend it! My roll the second night was not "amazing" or "blow your mind" but that could have been due to other things (not eating properly, not enough rest, etc.). But my roll was still pretty darn good :)
 
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