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Phenethylamines Low Dose Mescaline

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KattyKorner

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I'm wondering if anyone has experience with lower dose mescaline, as I am under a theory that it may be a worthy alternative to MDXX compounds. Thinking about 150 mg, give or take

It seems typically 2cb or similar are recommended for that role, but I think from reading about how mescaline has a lot of empathy, warmth, and euphoria, that lower doses might be a decent replacement, assuming it doesnt cause that uncomfortable "half in, half out" sensation that can come from psychedelic doses that arent quite high enough.

Any thoughts?
 
Mescaline might not be your best choice then. With mescaline you’ll be high as shit anazebealls and then all of a sudden your hit with a wave of clarity and sobriety before just somehow being back in it high as shit. It’s an amazing drug in its own right tho. I don’t consider anything like mdxx and I think that would be disrespectful to what is seriously the only drug I have ever taken that seems to have no bad side to its personality. There are no bad trips with mescaline. There is no discomfort. The euphoria you experience on it is organic and doesn’t feel spurned or unanatural because it’s not as if you feel the euphoria without cause. You’ll see a flower and just be filled with this awesome and powerful awe. It’ll be the most beautiful flower you’ve ever seen in your life and it won’t be the mescaline that makes you feel that way. It will literally be the most beautiful flower you have ever seen in your life and mescaline more just awakens you to the actual reality of things. I would love nothing more than to do mescaline. I so miss my cacti. They’re in California. Knowing my mom she probably threw them away. But god damn those cacti were my friends. I’d tripped off their branches like ten times in five years. Mescaline is the best drug on earth because it is quite literally indistinguishable from just having a great day. It’s a more beautiful day. A more perfect day. But it’s not because of the mescaline. That day was going to be the most perfect day no matter what. You just happened to take mescaline and it cemented the perception.
 
helpingout said:
Mescaline might not be your best choice then. With mescaline you’ll be high as shit anazebealls and then all of a sudden your hit with a wave of clarity and sobriety before just somehow being back in it high as shit. It’s an amazing drug in its own right tho. I don’t consider anything like mdxx and I think that would be disrespectful to what is seriously the only drug I have ever taken that seems to have no bad side to its personality. There are no bad trips with mescaline. There is no discomfort. The euphoria you experience on it is organic and doesn’t feel spurned or unanatural because it’s not as if you feel the euphoria without cause. You’ll see a flower and just be filled with this awesome and powerful awe. It’ll be the most beautiful flower you’ve ever seen in your life and it won’t be the mescaline that makes you feel that way. It will literally be the most beautiful flower you have ever seen in your life and mescaline more just awakens you to the actual reality of things. I would love nothing more than to do mescaline. I so miss my cacti. They’re in California. Knowing my mom she probably threw them away. But god damn those cacti were my friends. I’d tripped off their branches like ten times in five years. Mescaline is the best drug on earth because it is quite literally indistinguishable from just having a great day. It’s a more beautiful day. A more perfect day. But it’s not because of the mescaline. That day was going to be the most perfect day no matter what. You just happened to take mescaline and it cemented the perception.
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I appreciate the input.

I think it might be a good candidate, maybe, becuase of the effects you describe, the reality of everything is made more clear and euphoric.

For mescaline, I'll just say that I dont know of any sources, but from a non-experienced standpoint, the chemistry is pretty easy and straightforward. Depends on how far down the rabbit hole you want to go.
 
I have not tried it under 330 mg of the hydrochloride, but I found this dose specifically similar in intensity to a proper roll or like 20 - 22 mg 2C-B. Of course both mescaline and 2C-B are psychedelics and can bring forth uncomfortable material. They are also not entirely reliable in inducing the entactogenic state and you may instead find yourself in a lesson about wasting valuable 3,4,5-trimethoxybenzaldehyde for your entertainment (if you want to go the synthetic way). I found mescaline much warmer and magic than 2C-B, but it is also a bit more costly even when you make it yourself and of course it has a much longer duration.

But I'm all in favour for people spending time with psychedelics rather than entactogens, seems ultimately like the better choice.
 
I'm a big fan of low dose mescaline, but I also tend not to complain about "half-way turned on" states with psychedelics in general. No, I don't think low dose mescaline is a replacement for MDMA, rather it is a superior alternative. I say this partly because MDA/MDMA actually tend to fizzle for me, producing a rather unpleasant and anti-social melancholy state. I also don't like that the best effects are short-lived, and the long-term after effects (after at least 3 days, sometimes more like 7-10) are not so good.

Meanwhile I find low dose mescaline to be markedly stimulating, "heart-opening", and also peaceful and sublime.
I don't think it's as pro-social as MDMA is for most people. The only times I really enjoyed MDMA was when I had constant social stimulation, but with mescaline, I can have a tremendously positive experience in solitude. On a couple of low dose experiences, I went "adventuring", basically riding the bus to a museum or other point of interest. At the low level, the experience felt very controlled.

Keep in mind that it takes at least 4 hours for the experience to fully develop. Uneasy feelings may develop during the first few hours, and it's good to be familiar with that aspect and/or to stay in a safe location until you really settle into a positive experience. Moreover, even low doses can stimulate and keep you awake for up to 12 hours. It's usually best to dose mescaline within a few hours of waking up.

As for dose, I think 75-200 mg is roughly the range you want to aim for. Much beyond 200 mg and the experience becomes more properly psychedelic, and you get a whole new layer of effects with each additional 100 mg or so. At around 400 mg or so I think is where the experience begins to assume profound qualities.

Ironically my first two experiences with mescaline (in cacti) were low dose, and I couldn't help but compare them to MDMA in terms of the stimulation, euphoria, emotional opening, and so on. The irony was discovered in my third experience which probably came in close to 475 mg. At that level, it's just a completely different thing, like 100X as strong as the lower dose experience but also fully psychedelic with all kinds of visuals, "mescaline songs", and so on. To the point made by @xdrc about cost, the issue with low dose mescaline isn't so much that it's too expensive (in so far as I don't use it that frequently) but that the experience is so very much more at doses that use only 2-3X as much material. I'm also personally blessed with access to a variety of other phenethylamines which produce different kinds of entactogenic and psychedelic effects, pretty much all of which I find superior to MDMA as well.
 
I took a 100mg dose a number of years ago. I did it on my own in nature, riding my bike round the countryside. I visited a few stately homes and went to some pubs, It was one of my favourite experiences ever. I would have defiantly had an amazing day anyway but the mescaline gave such a calm peaceful feeling. There were a few jitters when it came on for a minute or two but it was very smooth with an afterglow the next day not a comedown.
 
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Looking into going partial cost for 7 g’s of mescaline online. No doubt concerned about scams and of course safety buying online. Seems like legit site, no indication that site is not legit.
 
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I have in the past used mescaline at both high and low doses, a few different salt moieties. I would say hands down, my favorite was mesc. hemisulfate monohydrate both for high and low doses - very very clean.

For low doses, I liked anywhere between 60-150mg, insufflated. I really liked the smell (no joke, it had an almost perfume/incense smell to it).

I preferred to sometimes do 180mg, sorted out into three 60mg lines, spaced about an hour or two apart.

At that level for me it was almost a “rounding out of my energy” coupled with increased body awareness (connection, not load). I never had an issue with sleeping on it, even at high doses.

I remember thinking at the time that the material was perfect, at any dose, and that insufflation worked significantly better than expected.
 
How are people getting low dose mescaline? Extracting it from cactus themselves? Cos all the "mescaline" you buy online has never even been in the same building as real mescaline.
 
I've had single peyote buttons of Lophophora diffusa (as well as fricii and koehresii) all act as fascinating stimulants in what I expected to be sub-threshold doses. This was likely due to background alkaloids though, not mescaline necessarily. Low doses of Lophophora williamsii are neat, but not as useful as a functional stimulant for me.
 
Mescaline was way underwhelming at 250mgs for me, not much euphoria, lots of laughs though and music enhancement. I think 150mgs is way too low. Things like methallylescaline arent as expensive and the dose is much lower so the cost benefit ratio is better its essentially the same experience I've read but ill try 800mgs of mescaline next time to compare. (Ive done 60mgs of methallylescaline before)
 
There's value in insight enhancement when you have questions you want to explore.

Shulgin had a high dose Mescaline + 50mg methamphetamine trip report which was highly positive. So I recently trailed 110mg Mescaline with 20mg Methamphetamine to very good effect in exploring personal and professional ideas in my life.

My next experience will be with 110mg alone to see if it compares to the combination.

Honestly, I would prefer without the 20mg Methamphetamine more due to the taboo around the drug. So if 110mg Mescaline can provide the same benefits in insight enhancement then it's a better option.

There's value in you doing the digging around in your personal life with lower doses that can be more valuable than the roller coast adventure park of high doses that can often be difficult to integrate or make sense of in a personal way.

Reminds me of a wonderful quote "How high can you go, before you can't get any higher"
 
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doubledog said:
I often use low dose mescaline (150mg) as an alternative or substitute for MDMA.

I think it's great in that role and I almost entirely stopped using MDMA as mescaline suits me much better.
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MDMA has a far different place in the pantheon. It’s shorter acting, more stimulating and extremely safe psychically compared to mescaline.

Many psychonauts also refer to it as a training drug for psychedelics like 2c-b as not to be overwhelmed with the psychedelic experience.
 
Leprechaun said:
Shulgin had a high dose Mescaline + 50mg methamphetamine trip report which was highly positive. So I recently trailed 110mg Mescaline with 20mg Methamphetamine to very good effect in exploring personal and professional ideas in my life.
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For being somebody who didn't take to cannabis, ayahuasca, or even mushrooms (relative to pure 4-subbed tryptamines), the coadministration of methamphetamine and mescaline is a fascinating move from Sasha, it seems he always leans in favor of absolute cognitive clarity when possible. Where was this experience report written? I'd love to give it a read.
Leprechaun said:
There's value in you doing the digging around in your personal life with lower doses that can be more valuable than the roller coast adventure park of high doses that can often be difficult to integrate or make sense of in a personal way.

Reminds me of a wonderful quote "How high can you go, before you can't get any higher"
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I've been trying to find adequate imagery to abstract this concept of the intensity of an experience negatively correlating with the ease of integration, the reason I tend to prefer guiding people on either super lightweight or super heavy duty trips is because I know how to approach this from either the low-dose or high-dose end of things, but locating where in the middling regions this lies can be tricky sometimes. One of the major ways I've worked to grow as someone who guides experiences is learning to intentionally apply things to upmodulate or downmodulate the intensity of an experience to the ideal place for whatever the session's goals are.
Leprechaun said:
Many psychonauts also refer to it as a training drug for psychedelics like 2c-b as not to be overwhelmed with the psychedelic experience.
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Are you saying people perspectivize MDMA as the training drug towards the more psychically deep 2C-B/mescaline? I have had MDMA induce straight up suicidality that I could not easily combat, but I've never had a single psychedelic do me that way.
 
Leprechaun said:
MDMA has a far different place in the pantheon. It’s shorter acting, more stimulating and extremely safe psychically compared to mescaline.

Many psychonauts also refer to it as a training drug for psychedelics like 2c-b as not to be overwhelmed with the psychedelic experience.
Click to expand...

What I meant is that low dose mescaline shares some similarities with MDMA (pro social empathic openness, good mood, stimulation) that it can be used in similar way.
Ofc it's still different experience.
 
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