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  • BDD Moderators: Keif’ Richards

Low Dose Antihistamines + Alcohol

Pothedd

Pothedd

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Aug 23, 2007
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Equals funked up.
Not large doses of any of them. And a little bit of weed sprinkled in.
But I think i may have stumbled upon an amazing combo that turns one alcoholic beverage into the equivalent of 6, drunk back to back, without the accompanying nausea.
I took about 50mg of diphenhydramine, and a believe a normal amount [whatever that is (1 actifed)] of pheniramine, hoping to catch a few zz's. (I think it was the pheniramine that did it, because I've noticed it has me more disoriented on its own than other antihistamines.)
Anyway, this wasn't doing the trick alone, as expected, so I smoked a bowl and skyped my girl.
Then I had some mighty cottonmouth, so I fetched myself a sangria and sat back down.
I emptied the drink into my face, and now I'm loaded. End of story.
At first it was just a mild fucked up feeling, but now I'm getting more tired. I'm thinking a smaller dose of anthistamines would be better if I wasn't actually trying to sleep.

I don't believe there's any danger in mixing small doses of either of these drugs, please correct me if I'm wrong.
But I think this would be a great way to make a small amount of alcohol go a long way.
"There's only one beer left!"
"Everyone take some benadryl, then split it!"
 
You haven't discovered anything new, unfortunately. :/
The general 'rule' is to use about 50mg of diphenhydramine to potentiate the alcohol (mostly drowsiness). Those without much experience should seriously avoid having more than four drinks. IMO it's best to use far more alcohol than diphenhydramine, i.e. 3 beers per benadryl (25mg diph). Also, too much diph can cause very dark hallucinations and a killer hangover (never mind the alcohol).

But you mentioned weed. A good amount of strong pot (sativa-dominant) combined with a good amount of dph can produce a very weird trip. I don't recommend more than 200mg. This combo is not exactly 'safe,' but it can be amazing with the right strain.
 
Lol, ok, it's not new.
But yes, you're idea of more alcohol, less dph, is right along the lines of what I figured upon. Got very, VERY drowsy.

I definitely need to invest in some sativa. I tend to smoke more indica. It helped me sleep, that's for sure.
That was the only problem. I need to figure out the right combination of alcohol, dph, and sativa so I don't pass out so quickly.
Maybe throw in a fourth drug that could help me stay awake. Caffeine comes to mind, though it makes me tired on its own...

Any ideas on good OTC or at least "easy to obtain" stimulants to add to the mix? Maybe something so simple as an energy drink... Taurine, etc...
 
Pothedd said:
Lol, ok, it's not new.
But yes, you're idea of more alcohol, less dph, is right along the lines of what I figured upon. Got very, VERY drowsy.

I definitely need to invest in some sativa. I tend to smoke more indica. It helped me sleep, that's for sure.
That was the only problem. I need to figure out the right combination of alcohol, dph, and sativa so I don't pass out so quickly.
Maybe throw in a fourth drug that could help me stay awake. Caffeine comes to mind, though it makes me tired on its own...

Any ideas on good OTC or at least "easy to obtain" stimulants to add to the mix? Maybe something so simple as an energy drink... Taurine, etc...
Click to expand...

IMO adding anything else (especially a stimulant) is a bad idea, and I have a good amount of experience with this kind of combo. You'll develop a tolerance where you still feel drowsy but you've learned to stay up anyway. Caffeine would probably make the already dirty 'high' feel even dirtier and it would remove from the more pleasant aspects of sedation. Maybe you can use more of the drugs which don't put you to sleep so easily, so that you can get pretty high without passing out.

The list to follow in that case (highest dose at the top):
Sativa
Alcohol
Indica
Diphenhydramine
 
Ok, so the best method for staying awake is simply building a tolerance.
Good to know.
A strong sativa may be my best bet. If only the dispensary in town was open on weekends...

Edit: Oh crap it is open on Saturdays!!! Damnit now I need to find a ride!
 
Pothedd said:
Ok, so the best method for staying awake is simply building a tolerance.
Good to know.
A strong sativa may be my best bet. If only the dispensary in town was open on weekends...

Edit: Oh crap it is open on Saturdays!!! Damnit now I need to find a ride!
Click to expand...

I hope you don't plan on doing this often.
Start at low doses... seriously. And have fun :)
 
I definitely don't plan on doing this often.
Frankly I don't enjoy alcohol, so that's why I was so amazed that I experienced any euphoria from the combination.

What can you guys say about yohimbine in this combination? It has mild stimulant effects, almost negligible, except when you try to go to sleep. Then you realise you're not tired, even though you are.
I kinda like yohimbine, in that it makes me more "normal." I don't crave cannabis constantly while on it, maybe due to a slight alleviation of a.d.d. symptoms (constant boredom plagues me 24/7).
 
Does it have to be diphenhydramine, could I use Phenergen and alcohol? Would it have the same effects?
 
I don't see why not. I'm not as well versed with promethazine, but most antihistamines have similar effects.
I noticed that doxylamine however was a lot weaker, with less euphoria, than diphenhydramine.
The only amount of Promethazine I had ever taken was a very large dose, mixed with dxm, that left me awake but lying with my eyes closed. It kinda sucked.
I'm not sure if lower doses would incorporate more euphoria with less drowsiness. If anyone has experience with phenergan let us know.
 
Hang on buddy.
You'll be fine as far as CNS depression goes, but if 50 mg knocks you out, 25mg plus 5 beers will also knock you out.
What Lord had suggested was that a tolerance needs to be built to the antihistamines before it stops knocking you out.
I took benadryl for the last 3 nights. On this third night I've mixed it with a couple drinks and I'm not really tired, though I was actually hoping to be.
Tolerance seems to build quickly to diphenhydramine.
 
I don't mind being 'knocked out' eventually, but I'm saying that the reason the 50mg dose knocked me out is because it was the first time I took it. I've taken it numerous times since then and haven't felt as effected.
 
Tolerance to the sedative effects of the first generation antihistamines (promethazine, diphenhydramine, etc) grows extremely rapidly. Sad things for people who use them recreationally, but a good thing for people who use them as antihistamines! :)
 
i don't think diphenhydramine and other antihistamines are good for getting fucked up with booze, i say screw the allergy meds and mix the booze with some benzos or opiates(or just drink it by itself).

i hate the feeling of anticholinergics(which sedative antihistamines are) even at regular doses.
 
Oh, awrighty then holden. I thought this would be your second time taking promethazine, which would undoubtedly end with sleep.

The tolerance is kinduv a bitch. I wasn't expecting it to grow that quickly.
100mg dph doesn't put me to sleep anymore. It did 3 nights ago...

Benzos and opiates are much nicer than anticholinergics, this is true, but they're far more dangerous to mix with alcohol.
Plus, if we had access to benzos and opiates we wouldn't even bother with antihistamines. Unfortunately, prescription medicines are not easily obtainable without said prescription.

I don't even like the effects of alcohol, but with an antihistamine it was slightly euphoric.
At least it was at first...
 
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