• 💊 OTHER DRUGS 💊 Welcome Guest
    Posting Rules Bluelight Rules
    Notable Threads 1 Notable Threads 2
    Dangerous Combos Addiction Support
    Emergency Services Benzo Guide v.1
    Addiction Stories Scary Case Studies
    Biology, Pharmacology & Drugs 101
  • Select Your Topic Then Scroll Down
    Alcohol Bupe Benzos
    Cocaine Heroin Opioids
    RCs Stimulants Misc
    Harm Reduction All Topics Gabapentinoids
    Tired of your habit? Struggling to cope?
    Want to regain control or get sober?
    Visit our Recovery Support Forums

Loperamide Insufflation

"Also, it may be possible for loperamide to bypass the blood brain barrier through insufflation. Though this remains unproven and is potentially unsafe to attempt.[4]" - Wikipedia

I think your answer is right there...
 
"When loperamide is taken by itself, it cannot readily cross the blood-brain barrier; however, when loperamide-containing nanoparticles are coated with polysorbate 80 and injected," - wikipedia.org

has anyone done this??? i would like to know how effective that is!!
 
oxycont1n said:
"When loperamide is taken by itself, it cannot readily cross the blood-brain barrier; however, when loperamide-containing nanoparticles are coated with polysorbate 80 and injected," - wikipedia.org

has anyone done this??? i would like to know how effective that is!!
Click to expand...


......

Snorting a little pill and coating nanoparticles are two completely different levels of ridiculous.

Also, don't be a troll just because I pointed out your douchery earlier.
 
ugh please no, why did i click this. god save me, not another 14 page thread about 1 or 2 people saying taking like 350mg of immodium AD gets you high and like 73 people say its fucking retarded and will just rape your stomach and you won't shit for a month and flame the shit out of that one guy who really loves immodium like more than psychoactive drugs like oxycodone or heroin, etc. his fucking BL screen name is something like "loper=a=mind" the guy loves it, can't wait til he gets here and starts ranting on how great it is, this should be fun to watch i'm not gonna say anything, just gonna sit back and watch the fighting and fun.

but i guess i've already said a decent amount. oh well.

IMMODIUM IS A FUCKING ANTI-DIARHHEA MEDICINE, YOU CAN'T GET HIGH ON IT, NUTMEG IS A BETTER DRUG.

i'm going insane, can't take anymore threads on immodium, xanax/benzo insuffilation, shooting percocets/vicodin, sniffing percs or vics, etc
 
Damn man, I was just curious.

Christ, forgive me for wondering man, not like I'm trying to ruin your day.

It was one of those "Wikipedia said it so it must be true" moments.
 
Don't do it. It will burn nose like hell. There has been a number of people trying it before. ;)

And 350mg of loperamide won't make you not shit for a month. That's a real emergency for a naloxone shot.
 
enoughorangejuice? said:
ugh please no, why did i click this. god save me, not another 14 page thread about 1 or 2 people saying taking like 350mg of immodium AD gets you high and like 73 people say its fucking retarded and will just rape your stomach and you won't shit for a month and flame the shit out of that one guy who really loves immodium like more than psychoactive drugs like oxycodone or heroin, etc. his fucking BL screen name is something like "loper=a=mind" the guy loves it, can't wait til he gets here and starts ranting on how great it is,

IMMODIUM IS A FUCKING ANTI-DIARHHEA MEDICINE, YOU CAN'T GET HIGH ON IT
Click to expand...

ROFLMAO - I agree totally!!!!!!!!!
 
"Also, it may be possible for loperamide to bypass the blood brain barrier through insufflation. Though this remains unproven and is potentially unsafe to attempt.[4]" - Wikipedia

Again that came from wikipedia fellas...if you read the "interesting" part about it...read on. It's not worth it fellas. Wish I had an "end thread" button, this thread is pretty much useless......
 
i have no idea what nanoparticles are so i didnt know how rediculous my question was.
 
oxycont1n said:
i have no idea what nanoparticles are so i didnt know how rediculous my question was.
Click to expand...

I actually agree with the dude...he was just trying to gain knowledge...isn't that what these forums are about?
 
you%20gonna%20get%20raped.jpg
 
dudes what the fuck? cant even have an intelligent conversation here without calling eachother deuches and screaming? jesus. and actualy mr euphoric orange juice, you are completely INCORRECT so dont go flaming like a mofo when you actualy are not right. loperamide does have Weak Mu activity and at higher doses delta and kappa activity. it will get you high. no one was taking 350 mg. more like 35. in opiate tolerant individuals it does not stop them up any worse than a regular opiate and several people on this board myself included have been very high off loperamide. it also, for about everyones whos tried it, really does get rid of those wds. so dont go yellin shit you cant back up, this was a legit question, the guy was trying to learn, and there really isnt a ton of info on this so i think discussion of it would be very beneficial.
 
also, i have no idea how this guys post qualified him as "trolling"

Originally Posted by oxycont1n quote:
"When loperamide is taken by itself, it cannot readily cross the blood-brain barrier; however, when loperamide-containing nanoparticles are coated with polysorbate 80 and injected," - wikipedia.org

has anyone done this??? i would like to know how effective that is!!"
:end quote


posted by Virtuoso quote:

"Snorting a little pill and coating nanoparticles are two completely different levels of ridiculous.

Also, don't be a troll just because I pointed out your douchery earlier."

all the man asked was, has anyone tried it. lets all chill. :)
 
klowns said:
dudes what the fuck? cant even have an intelligent conversation here without calling eachother deuches and screaming? jesus. and actualy mr euphoric orange juice, you are completely INCORRECT so dont go flaming like a mofo when you actualy are not right. loperamide does have Weak Mu activity and at higher doses delta and kappa activity. it will get you high. no one was taking 350 mg. more like 35. in opiate tolerant individuals it does not stop them up any worse than a regular opiate and several people on this board myself included have been very high off loperamide. it also, for about everyones whos tried it, really does get rid of those wds. so dont go yellin shit you cant back up, this was a legit question, the guy was trying to learn, and there really isnt a ton of info on this so i think discussion of it would be very beneficial.
Click to expand...


The point he was trying to make was that this thread has been made countless times. The op should of used the search engine.
 
yeah, i see that,
but you also have to understand, there really is NOT a lot, or barely any info about this anywhere. i know its been discussed before, but not very in depth, and usualy the threads consist of alot of flaming, and no real information. the only way to really get to know more about this is to disccus our personal experiences with it. if you have a problem with his thread, i suggest you just stay out of it.
im sure he used the fucking search engine, found one or 2 threads title snorting loperamide, and actualy found no useful information in there. seems like its msotly jsut opinion going around about this, we need more solid information, and the shit about polysorbate 80 actualy is really fascinating. i mean shit, how many times a day do you see a thread titled whats teh best way to take my oxy? and people always reply to them. or "is coke good?"
fuck, if people never posted there questions, (may be hard to believe, but some people do use saerch engines, and still have questions) and felt that they would be flamed to death for asking a question , then we wouldnt have any fucking forums here. peoples ideas change, what we think we know about certain chemicals change, and if I personaly read a few half assed threads about immodium, and i didnt know much about it, i would post the same damn question.
id like to know in comparison to morphine or somethign, the actualy binding affinitys for loperamide for mu delta and kappa, and its analgesic potency at higher than recomended doses. although i believe it does vary in differetn people , ie some people can get really high off of immodium while others swear they cant.
 
klowns said:
yeah, i see that,
but you also have to understand, there really is NOT a lot, or barely any info about this anywhere. i know its been discussed before, but not very in depth, and usualy the threads consist of alot of flaming, and no real information. the only way to really get to know more about this is to disccus our personal experiences with it. if you have a problem with his thread, i suggest you just stay out of it.
im sure he used the fucking search engine, found one or 2 threads title snorting loperamide, and actualy found no useful information in there. seems like its msotly jsut opinion going around about this, we need more solid information, and the shit about polysorbate 80 actualy is really fascinating. i mean shit, how many times a day do you see a thread titled whats teh best way to take my oxy? and people always reply to them. or "is coke good?"
fuck, if people never posted there questions, (may be hard to believe, but some people do use saerch engines, and still have questions) and felt that they would be flamed to death for asking a question , then we wouldnt have any fucking forums here. peoples ideas change, what we think we know about certain chemicals change, and if I personaly read a few half assed threads about immodium, and i didnt know much about it, i would post the same damn question.
id like to know in comparison to morphine or somethign, the actualy binding affinitys for loperamide for mu delta and kappa, and its analgesic potency at higher than recomended doses. although i believe it does vary in differetn people , ie some people can get really high off of immodium while others swear they cant.
Click to expand...

Exactly...thats why we have forums. That was the post I was going to make but I think I would have used a few more four letter words...when people ask real questions and someone tries to downgrade them that shit really pisses me off.
 
klowns said:
yeah, i see that,
but you also have to understand, there really is NOT a lot, or barely any info about this anywhere. i know its been discussed before, but not very in depth
Click to expand...

I know where youre coming from in defending this guy, I think you are right in doing it because it is a different, more specific question than what has been asked before.

The only thing i disagree with is what I bolded. Loperamide itself has been discussed in depth, and this subject has been touched on, meaning injecting nanoparticles has not been discussed in depth and no one ever really had a definitive answer on snorting it.

So basically I dont know why I made this post. It didnt take us any further in the discussion.
 
You must log in or register to reply here.
Top