Long weekend ahead... (MDA, LSD, MDMA)

[Folley]

It's been said before that there is no cross tolerance for MDMA and MDA. When i first took MDA, I had a pretty decent tolerance to MDMA and I got virgin wrecked from the MDA like it was my first time. However, since they react on the same or similar receptors, it seems it would make sense that they are cross tolerant. Here's a little study and some comments suggesting they aren't.

Uhhhh dude, that makes no sense at all... MDMA and MDA both cause a release of serotonin in LARGE amounts, that alone is going to cause a cross tolerance.



The first link is the only thing that supports that... and it seems very flawed.

No, I think racemic MDMA and racemic MDA will share some tolerance due to sharing activities (serotonin release)

Although, a paper showed that MDA and MDMA are not cross tolerant in rats despite the clear similarity in effects. They note that MDA substitutes for the hallucinogens LSD/DOM in drug discrimination studies but MDMA does not. Also it goes on to note the actions of MDA were opposed by a 5-HT antagonist whereas the effects of MDMA were better opposed by a norepinephrine antagonist.

Also interesting to note is that MDMA and methamphetamine showed cross tolerance.

MDA is still a good monoamine releaser - MDMA is just more of a "stimulant": more monoamine release & much less active at 5-HT2a

If you're going to say that MDMA and MDA are not completely cross tolerant with each other, you're gonna need more than that they may not act on all of the same receptor sites, but the 5-HT system is still the main area in which it works

Hey Folley thanks for getting back to me, just to clarify though, are you saying what I have doesn't look like MDMA? (I know i have test to be sure of anything) Also with the reagent tests aren't you testing for MDXX and not MDMA specifically?

Of course I can't say for sure, but that sure looks like all the methylone I've seen If you only get the Marquis you won't be able to tell MDMA from MDA or MDE, but you will be able to spot 5/6-APB and possibly MDAI


If you get the Simons kit you can tell whether your sample is MDMA/MDA, or meth/amphetamine


The Mecke reagent will tell you if there is MDMA or DXM in it, and the mandelin will alert you to ketamine and PMMA.



Marquis is the best fr differentiating chemicals, but I recommend getting them all if you want to be certain

 

[blah blah]

It made sense. When i said it'd make sense that they are cross-tolerant, that was just me stating some inner monologue, questioning that they aren't cross-tolerant. Then i posted those links stating they aren't. I question it too, i'm simply sharing other avenues is all.

 

[Folley]

OK I think I have you confused then lol

I think what that study is trying to say is that MDA has more of a cross tolerance with psychedelics, and MDMA is more cross tolerant with amphetamines... IDK, it's from 1990 and it doesn't really explain the claims it makes at all

 

[Panda51]

Only one word can explain this weekend. Wow. I'll do a short run through of everything.

I was actually caught off guard by the Acid. I fried with a 4 of my friends on Friday night like I had originally planned. I took the tab around 10PM and was really excited for the experience. There were two of us that had never fried before so we were pumped... one of my friends who does LSD often was planning on dropping 3 tabs because he has a natural tolerance to it. His gf told him he really should only start with one because apparently they were stroooooong tabs. He dropped 2 at the same time.

At about +:40 I started feeling the come up. My stomach was feeling light/numb/uneasy (but this didn't last long) and my body almost felt like I was starting to roll (sensitive skin, tingling toes, light head, etc).

At +1:00 we were all feeling the tabs. All of us were really giggly and spacey. My friend who dropped 2 was complaining about his stomach hurting pretty bad. It passed within 10 mins and we decided it was time to go to a stage.

At about +1:25 we squeezed up to the front row of Benny Benassi and he was dropping a pretty fucking heavy set. We must have been standing right next to the subs, because I could literally feel my brain shaking in my skull every time the bass dropped. That started making me trip hard. I remember watching the lights and starting to notice them doing things that weren't actually possible (like completely and falling onto the stage and shattering, just to see that they had never really fallen in the first place). Having used psychedelics before, this didn't bother me at all. It just made me laugh hysterically while watching Benny lol.

at +2:00 we decided to go to another stage. I remember walking through a huge crowd of people and finding it really hard to navigate through them. I also thought for some reason that people walking up and down the stairs were seriously the funniest thing I had ever seen in my life haha. At this point, my friend who had dropped 2 was frying really, really hard. He was confused as to what was going on, but felt bad that we weren't seeing as many artists as we'd like to... so we decided to head to Kaskade.

At +2:30 we got to the main stage where Kaskade had just started his set. We began to squeeze our was through the crowd so we could see the stage. I was following one of my friends who was leading the way (he was sober) and I turned around to see people going in all different directions. I saw my friends and told them to keep following. They were all really overwhelmed with the amount of people that were pushing by us, and I think once I picked up on that... I became really overwhelmed too. I knew I had to get out of that crowd. We walked out of the crowd and went to to sit down where we could still hear his set. At this point, my friend who took two was FUCKED UP. I could tell that he was getting a bit scared and confused.

+3:00 I had to get away from my sober friends. They completely understood and said they wanted to go listen to some dubstep anyways. I felt like interacting with people that weren't on my level was giving me bad vibes.

+3:30 I was full blown hallucinating. The ground I was sitting on became very gritty and animated. I could also see lines in EVERYTHING. Reds and Blues seemed to be my main colors of the night when I was looking at people and things (which was odd for me because I'm used to Reds and Greens). It was hard seeing people that were cracked out on bad pills... those people looked really scary to me, and at one point they were starting to have the skin peeled off from their faces. It was really strange. I also noticed that any physical flaws that my friends had seemed to stand out 10x more than they usually would have.

+4:00 I found that standing in florescent light was really freaking me out. And I didn't like seeing people under it. I think it's because it reminds me of work or school or something. Strange. We walked outside and went to get water. Upon refilling it, I remember looking into the aluminum bottle before taking a sip and it almost looked like I was drinking mercury. It looked like metallic liquid. I thought it was fucking cool so I poured it on my hand, watching it splatter onto my skin, then onto the floor.

+4:30 I began to peak. I again started finding things a bit overwhelming. I had to stop walking so I could kind of take in everything that was going on and it was at that point that I noticed I didn't see my friends. Immediately I panicked and I was completely terrified. I locked up and I seriously didn't even know how to walk I was so scared. Seeing everyone rolling made me never want to roll again. I remember everyone looking so dirty. Within about 2 mins, one of my friends ran up and grabbed me and told me to come with her. I was so relieved and a wave of euphoria and safety rushed over me. At that point I started to feel really giggly again and relaxed.

+6:00 it was at this point that the epic hallucinations started to go away, and things got a lot more calm and tracey. We went to a stage and got pretty close and we didn't feel overwhelmed. We stayed for about another 30 mins and decided it was time to go home. We left around 5 and got back to the hotel about 6. I drank some more water, had 2mg's of melatonin, half a Xanax bar, and crashed.

All and all I really liked the experience. I wouldn't ever do acid by itself at an event that large again though. I would be open to Candyflipping!

Oh, and by the way I rolled two days. Good amount of MDMA, about 90mg. I had three 90mg caps day 2 and day 3 and actually, day 3 I rolled much harder than day 2! At the end of the night we all went back, made egg and bacon sandwiches, talked for a bit, and fell asleep! Woke up Monday morning and took a shower just to hear someone banging on my door. All of our friends were already at the pool and had slept from 6AM to 2PM lol. Went to the bar by the pool, had a few beers, and swam for a couple hours! Flew home today and I feel great! 5-HTP, St. Johns Wort, Sam-e, and Kava Kava did wonders! All combined with a multivitamin, a few hours of sleep a night, and food

Besides having a slightly sore throat, sore legs (from dancing), and chapped lips... I had an AMAZING weekend!

TLDR- Acid was awesome, but overwhelming at an event of that caliber... and I ended up rolling two days in a row and I'm just fine!

 

[anothernewparadigm]

Nice lil report there the acid sounds awesome. Firmly on the to do list, but perhaps not at a festival I don't like the idea of getting separated from friends on it for a first time.

 

[Panda51]

Nice lil report there the acid sounds awesome. Firmly on the to do list, but perhaps not at a festival I don't like the idea of getting separated from friends on it for a first time.

Yeah I would just try it with some friends.... or maybe in a downtown-ish setting if you know what I mean haha

 

[slackhands]

Trust me, there is no one human on this planet that is safe from MDMA's neurotoxic side effects.. you may not feel it now, but keep it up and it will hit you full force. Best to play things safe than to risk permanent damage and 5-HT downregulation... take this from me, I used to roll every week and think it was just fine... but now a year after than and 6 months from my last roll, I still haven't recovered...

Just be safe is all I'm sure you'll have a good time either way

I've never understood why/how people manage to roll each week. MDMA is clearly some hardcore substance you're taking. I don't know anything about the science side of things, but it makes sense to be sceptical about such a mind altering substance. Tbh MDMA really freaks me out at times(whilst I'm on it) and last time I kept spacing out loads, and I'm still not sure whether something I think I did actually happened or not.
However I'm quite an impulsive person normally and pay too much attention to things often dwelling on them and making them seem worse. On the flip side I can definitely see why people do take MDMA weekly in terms of it's undeniable positive side effect,lol.

 

[anothernewparadigm]

Yeah I would just try it with some friends.... or maybe in a downtown-ish setting if you know what I mean haha

Yea I have been thinking about giving it a go at a house party type with just a handful of close friends there, all of whom are going to roll or trip. That said, I like the idea of being outside while tripping, but I guess I won't know until I try it.

 

[BluLait]

Let me just preface this with- I haven't rolled in a fairly long time (8 months or so), and NEVER in this excess. But I'm going to a weekend event and I want to go big. This is going to be my last time all of my friends will be together for a long time. I tried searching the forums for someone else that was or has been in the same boat but couldn't find anything. So... let me know what you guys think.

DAY 1: One tab of LSD (Possibly two. I'm a first timer, although I have used peyote, shrooms, DMT, etc. I've always done well with psychedelics.)
DAY 2: 90mg of MDA, a few hours later, 90mg MDMA (or vice versa?)
DAY 3: 280mg MDA (3 total)

I'm prepared with melatonin for the sleep, 5-HTP & Sam-e after the weekend for the comedown. I know not to take either within 72 hours of MDxx consumption. All feedback is appreciated. I'm open to suggestions on changing anything up.

Also: I've read things on Prozac reducing neurotoxicity after MDxx use... if I could procure some, could it be used in addition to the 5-HTP and Sam-e? Or would I need to hold off on the 5-HTP?

Thank you in advance for all of your feedback

Wait, what festival was this at?

 

[thelastclubkid]

Only one word can explain this weekend. Wow. I'll do a short run through of everything.

I was actually caught off guard by the Acid. I fried with a 4 of my friends on Friday night like I had originally planned. I took the tab around 10PM and was really excited for the experience. There were two of us that had never fried before so we were pumped... one of my friends who does LSD often was planning on dropping 3 tabs because he has a natural tolerance to it. His gf told him he really should only start with one because apparently they were stroooooong tabs. He dropped 2 at the same time.

At about +:40 I started feeling the come up. My stomach was feeling light/numb/uneasy (but this didn't last long) and my body almost felt like I was starting to roll (sensitive skin, tingling toes, light head, etc).

At +1:00 we were all feeling the tabs. All of us were really giggly and spacey. My friend who dropped 2 was complaining about his stomach hurting pretty bad. It passed within 10 mins and we decided it was time to go to a stage.

At about +1:25 we squeezed up to the front row of Benny Benassi and he was dropping a pretty fucking heavy set. We must have been standing right next to the subs, because I could literally feel my brain shaking in my skull every time the bass dropped. That started making me trip hard. I remember watching the lights and starting to notice them doing things that weren't actually possible (like completely and falling onto the stage and shattering, just to see that they had never really fallen in the first place). Having used psychedelics before, this didn't bother me at all. It just made me laugh hysterically while watching Benny lol.

at +2:00 we decided to go to another stage. I remember walking through a huge crowd of people and finding it really hard to navigate through them. I also thought for some reason that people walking up and down the stairs were seriously the funniest thing I had ever seen in my life haha. At this point, my friend who had dropped 2 was frying really, really hard. He was confused as to what was going on, but felt bad that we weren't seeing as many artists as we'd like to... so we decided to head to Kaskade.

At +2:30 we got to the main stage where Kaskade had just started his set. We began to squeeze our was through the crowd so we could see the stage. I was following one of my friends who was leading the way (he was sober) and I turned around to see people going in all different directions. I saw my friends and told them to keep following. They were all really overwhelmed with the amount of people that were pushing by us, and I think once I picked up on that... I became really overwhelmed too. I knew I had to get out of that crowd. We walked out of the crowd and went to to sit down where we could still hear his set. At this point, my friend who took two was FUCKED UP. I could tell that he was getting a bit scared and confused.

+3:00 I had to get away from my sober friends. They completely understood and said they wanted to go listen to some dubstep anyways. I felt like interacting with people that weren't on my level was giving me bad vibes.

+3:30 I was full blown hallucinating. The ground I was sitting on became very gritty and animated. I could also see lines in EVERYTHING. Reds and Blues seemed to be my main colors of the night when I was looking at people and things (which was odd for me because I'm used to Reds and Greens). It was hard seeing people that were cracked out on bad pills... those people looked really scary to me, and at one point they were starting to have the skin peeled off from their faces. It was really strange. I also noticed that any physical flaws that my friends had seemed to stand out 10x more than they usually would have.

+4:00 I found that standing in florescent light was really freaking me out. And I didn't like seeing people under it. I think it's because it reminds me of work or school or something. Strange. We walked outside and went to get water. Upon refilling it, I remember looking into the aluminum bottle before taking a sip and it almost looked like I was drinking mercury. It looked like metallic liquid. I thought it was fucking cool so I poured it on my hand, watching it splatter onto my skin, then onto the floor.

+4:30 I began to peak. I again started finding things a bit overwhelming. I had to stop walking so I could kind of take in everything that was going on and it was at that point that I noticed I didn't see my friends. Immediately I panicked and I was completely terrified. I locked up and I seriously didn't even know how to walk I was so scared. Seeing everyone rolling made me never want to roll again. I remember everyone looking so dirty. Within about 2 mins, one of my friends ran up and grabbed me and told me to come with her. I was so relieved and a wave of euphoria and safety rushed over me. At that point I started to feel really giggly again and relaxed.

+6:00 it was at this point that the epic hallucinations started to go away, and things got a lot more calm and tracey. We went to a stage and got pretty close and we didn't feel overwhelmed. We stayed for about another 30 mins and decided it was time to go home. We left around 5 and got back to the hotel about 6. I drank some more water, had 2mg's of melatonin, half a Xanax bar, and crashed.

All and all I really liked the experience. I wouldn't ever do acid by itself at an event that large again though. I would be open to Candyflipping!

Oh, and by the way I rolled two days. Good amount of MDMA, about 90mg. I had three 90mg caps day 2 and day 3 and actually, day 3 I rolled much harder than day 2! At the end of the night we all went back, made egg and bacon sandwiches, talked for a bit, and fell asleep! Woke up Monday morning and took a shower just to hear someone banging on my door. All of our friends were already at the pool and had slept from 6AM to 2PM lol. Went to the bar by the pool, had a few beers, and swam for a couple hours! Flew home today and I feel great! 5-HTP, St. Johns Wort, Sam-e, and Kava Kava did wonders! All combined with a multivitamin, a few hours of sleep a night, and food

Besides having a slightly sore throat, sore legs (from dancing), and chapped lips... I had an AMAZING weekend!

TLDR- Acid was awesome, but overwhelming at an event of that caliber... and I ended up rolling two days in a row and I'm just fine!

thats a pretty awesome report... it reminds me of why i want do trip one day at the festival this weekend.... the only thing is just like you i get the occasional overwhelmed feeling with acid/mushrooms which can kinda suck when you are around 30,000 people...