Long-term cannabis use can double risk of psychosis

slimvictor

Bluelight Crew
Joined
Dec 29, 2008
Messages
6,477
Location
"Darkness cannot be dissipated with more darkness.
http://www.reuters.com/article/idUSTRE6201LW20100301

LONDON (Reuters) - Young people who smoke cannabis or marijuana for six years or more are twice as likely to have psychotic episodes, hallucinations or delusions than people who have never used the drug, scientists said on Monday.

The findings adds weight to previous research which linked psychosis with the drug -- particularly in its most potent form as "skunk" -- and will feed the debate about the level of controls over its use.

Despite laws against it, up to 190 million people around the world use cannabis, according to United Nations estimates, equating to about 4 percent of the adult population.

John McGrath of the Queensland Brain Institute in Australia studied more than 3,801 men and women born between 1981 and 1984 and followed them up after 21 years to ask about their cannabis use and assessed them for psychotic episodes. Around 18 percent reported using cannabis for three or fewer years, 16 percent for four to five years and 14 percent for six or more years.

"Compared with those who had never used cannabis, young adults who had six or more years since first use of cannabis were twice as likely to develop a non-affective psychosis (such as schizophrenia)," McGrath wrote in a study published in the Archives of General Psychiatry journal.

They were also four times as likely to have high scores in clinical tests of delusion, he wrote, and a so-called "dose-response" relationship showed that the longer the duration since first cannabis use, the higher the risk of psychosis-related symptoms.

A study by British scientists last year suggested that people who smoke skunk, a potent form of cannabis, are almost seven times more likely to develop psychotic illnesses such as schizophrenia than those who smoke "hash" or cannabis resin.

Previous studies had also suggested smoking cannabis can double the risk of psychosis, but the British study was the first to look specifically at skunk. Skunk has higher amounts of the psychoactive ingredient THC which can produce psychotic symptoms such as hallucinations, delusions and paranoia.

McGrath said, however, that "the nature of the relationship between psychosis and cannabis use is by no means simple" and more research was needed to examine the mechanisms at work.

As part of his study, McGrath and his team looked at links between cannabis use and psychotic symptoms among a group of 228 sibling pairs and found the association still held. This suggests other influences like genes or the environment were less likely to be responsible for the psychosis, they said.

A international group of drug policy experts published a book earlier this year arguing that laws against cannabis have failed to cut its use but instead led to vast numbers of arrests for drug possession in countries like Britain, Switzerland and the United States, which cause social division and pointless government expense.
 
"Compared with those who had never used cannabis, young adults who had six or more years since first use of cannabis were twice as likely to develop a non-affective psychosis (such as schizophrenia)," McGrath wrote in a study published in the Archives of General Psychiatry journal.

Schizophrenia is a highly affective disorder. How does this researcher not know the DSM??

They were also four times as likely to have high scores in clinical tests of delusion, he wrote, and a so-called "dose-response" relationship showed that the longer the duration since first cannabis use, the higher the risk of psychosis-related symptoms.

This seems a little more likely. 'Negative' symptoms of schizophrenia include apathy, lack of emotion, poor or nonexistant social functioning, disorganized thoughts, difficulty concentrating and following instructions, difficulty completing tasks, and memory problems. Heavy smokers may experience all of these. Doesn't mean they are schizophrenic.

I would like to see this experiment replicated over and over. Although we still don't know what exactly causes schizophrenia, we know some correlations. Being born in the winter or spring gives you a higher chance of developing schizophrenia, for example. Most doctors of psychology I've talked to about the topic of MJ and schizophrenia claim that while it probably doesn't cause schizophrenia, it might lead to earlier onset. The others ones claimed they didn't know for lack of knowledge or evidence. If we can prove that marijuana truly leads to schizophrenia, we'll become closer to treating this mysterious disease.
 
This "study" means nothing, because there is no objective test for "schizophrenia."

Schizophrenia is not a disease, its a grouping of symptoms only. You cannot perform any kind of objective biopsy to confirm its existence.

The diagnosis is completely reliant on the opinion of a psychiatrist, and its based solely upon the subjective interpretation of behavior. Its a completely flawed and useless diagnostic method, which makes psychiatric studies extremely vulnerable to manipulation.

Furthermore the term "schizophrenia" covers such a wide range of possible aberrant behaviors that its foolish to assume all cases of schizophrenia are caused by the same biochemical mechanism. There has never been a study linking schizophrenia with any specific biochemical mechanism in the brain.

The human brain is more complex, and the human mind more nuanced, than we could imagine even in our wildest dream. Sometimes people exhibit very unusual forms of behavior, labeled as "psychosis" by psychiatrists. I would venture to guess that people prone to these unusual forms of behavior, are probably more likely to smoke cannabis than their more socially-ordinary peers.

What this study tells us is that cannabis use is correlated with goofy behavior and illogical thought progression. It sheds no light on the question of whether or not cannabis can causally increase ones risk of experiencing "psychosis".
 
This "study" means nothing, because there is no objective test for "schizophrenia."

Schizophrenia is not a disease, its a grouping of symptoms only. You cannot perform any kind of objective biopsy to confirm its existence.

The diagnosis is completely reliant on the opinion of a psychiatrist, and its based solely upon the subjective interpretation of behavior. Its a completely flawed and useless diagnostic method, which makes psychiatric studies extremely vulnerable to manipulation.

Furthermore the term "schizophrenia" covers such a wide range of possible aberrant behaviors that its foolish to assume all cases of schizophrenia are caused by the same biochemical mechanism. There has never been a study linking schizophrenia with any specific biochemical mechanism in the brain.

The human brain is more complex, and the human mind more nuanced, than we could imagine even in our wildest dream. Sometimes people exhibit very unusual forms of behavior, labeled as "psychosis" by psychiatrists. I would venture to guess that people prone to these unusual forms of behavior, are probably more likely to smoke cannabis than their more socially-ordinary peers.

What this study tells us is that cannabis use is correlated with goofy behavior and illogical thought progression. It sheds no light on the question of whether or not cannabis can causally increase ones risk of experiencing "psychosis".
^This.

Correlation is not causation. It is pretty obvious (if not flat-out well-known) that people with psych disorders are far more likely to use drugs long term...
 
Marijuana does not cause schizophrenia.

Schizophrenia is real.

Mood disorders and schizophrenia are two vastly different things.

Weed works wonders for some people with mood disorders.
 
Schizophrenia is real.

It depends on what you mean by "real". There certainly is an entry in the DSM called "schizophrenia", which lists a lot of symptoms, and some people certainly do exhibit those symptoms. That definitely is true.

But if by "real" you are trying to insinuate that schizophrenia is an actual physiological pathology like diabetes with a specific causal mechanism, then you're incorrect. Schizophrenia is not a neurological disease, it is only an arbitrary categorization of behavioral symptoms.

There is not a medical disease called "schizophrenia". Its only real if you accept the overtly fabricated, and completely unproven, premises of biological psychiatry.
 
Oh God.. This is the article responsible for my parents telling me it smells like skunk in the house! And that I'm developing schizophrenia.
 
Schizophrenia is not a neurological disease, it is only an arbitrary categorization of behavioral symptoms...

Good: be skeptical about these things. It'll help you decide whether or not to go into psychiatry for the next 4 decades. After a few years in the industry, I want nothing more to do with it--the sooner I can get my medical license, the sooner I can get the hell away from Mental Health.

If you're really curious, get a gig at an inpatient facility, homeless shelter or psychiatric group home.
 
^You can't assert causation like that, though.

In order to prove causation you must understand the causal mechanism and verify that interrelationship experimentally.

All we know for sure is that people who are likely to end up in front of a psychiatrist (either willfully or by means of coercion) and be labeled as "schizophrenic" in the opinion of the psychiatrist, are also likely to have used cannabis frequently.

There's a vast number of possible factors influencing the correlation. Any claim of causation in such a situation is a product of sloppy and illogical analysis.
 
Can't cannabis trigger schizophrenia if schizophrenia is in the family? Sorry if i sound like a complete dumb ass, just curious.
 
Top