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listing of common/uncommon opiates (needs checking)

Well researched. What a fine group of substances, I've been wiping the drool off of the keyboard as i was reading. What NK said about DXM is true and Tramadol is not an opiate.:)
 
Naloxone is readministered in case of methadone or levorphanol overdose, heroin is quite short acting and shouldn't require a second shot, though I am not sure about this. I am sure that readministration is almost necessary with levorphanol.
 
I have seen a handful of cases where Naloxone had to be administered 2 times in order to pull the person out of an OD. Even that isn't enough on some occasions and defibleration had to be preformed if the heart has stopped beating or the person has to have intubation in order to restore breathing capabilities.

Question:

Does anybody know the current standings of LAAM? Is it still being used? Is it being phased out? I know there has been some health concerns surrounding its use but I haven't really looked into it. Anybody?
 
DEXTROMETHORPHAN is NOT an opiate. It is often confused with one because two dimensionally it looks like one. Its stereo-isomer, levomethorphan, IS an opiate (a schedule II one, as well). DXM is also mistakenly considered an opiate because like opiates it reduces the cough reflex. But, it does this in a totally different way than opiates do. The fact that both opiates and DXM do this is a coincidence. DXM is NOT an opiate. Its stereoisomer, however, is.
 
Morphine is available in these capsules filled with hard white balls, called Kadian. I think there are 30mg, 50mg, 100mg. They are like major time release, meant to last 12hrs or something.
 
Also missing from the list is oxymorphone (and hundreds of others if you're not limiting yourself to what can be found in the USA).
 
Yea I left out a couple here and there... (probably under the influence of the dreaded poppy)

Rattle of some of the names of the others ones I didnt add(at least ones that are scripted on occasion) if you want.
 
sufentanil, afentanil, dihydrocodeine, dipipinone, ketobemidone.... there are lots, but the ones you did not list are ones most people would never encounter, let alone hear of. I mean...carfentanil (10,000 times more potent than morphine) is used for weapons and to stun large animals (Wildnil darts).... not something one would fuck around with on a boring rainy saturday night (unless ya had one helluva tolerance, hehe).
 
Scripted in the US (to people or animals):
Oxymorphone (15X morphine) - trade name: Numorphan supposotories and injection only,
etorphine (immobilon - for big game),
alfentanyl (this is actually quite common in surgery, as it has a 3 minute half life, so an IV drip will keep people under until its removed, then they wake up almost immediately, this is really popular in outpatient anaestesia)(wisdom teeth/breast enlargement).

Obscure:
Ethyl-morphine - looks like codeine except an ethyl group at C-3 instead of a methyl, even weaker - prescribed in europe!
Mono-acetyl-morphine (what heroin converts into in the brain),
Dihydroetorphine (Looks like etorphine but EVEN STRONGER - strongest in the etorphine family),
noroxymorphone, (Oxymorphone without a methyl group at the N - 8X morphine potency)
desomorphine, (Morphine without oxygen attached to C-3 and C-6, 8X morphine)
normorphine, (Morphine without a methyl group attached to the N - 1/2Morphine potency)
Metopon, (oxymorphone analog which did not cause physical dependance in monkeys or other primates! Caused mild withdrawals in man, and was abandoned in the 1970s due to an ability to substitute for morphine [euphoric potential])
heterocodeine (despite the name, its 10X morphine - aka 6-O-methyl-morphine),
oxymorphazone - oxymorphone analog which lasts ~48 hours
naltrindole (research antagonist - cool because it looks like a tryptamine attached to an opiate)
nalmefene (antagonist prescribed for those who have liver failure - in the US even),
6-methylene-6-desoxy-dihydromorphinone - Looks like hydromorphone with a Methylene group at the 6 position instead of anything else 80X morphine - mentioned in some college texts

Clandestine:
Alpha Methyl Fentanyl (aka 4-methyl),
Prodine (a meperidine analog - 10X morphine) comes in alpha and beta flavors.
 
who mE? said:
Scripted in the US (to people or animals):
Oxymorphone (15X morphine) - trade name: Numorphan supposotories and injection only,
etorphine (immobilon - for big game),
alfentanyl (this is actually quite common in surgery, as it has a 3 minute half life, so an IV drip will keep people under until its removed, then they wake up almost immediately, this is really popular in outpatient anaestesia)(wisdom teeth/breast enlargement).

Obscure:
Ethyl-morphine - looks like codeine except an ethyl group at C-3 instead of a methyl, even weaker - prescribed in europe!
Mono-acetyl-morphine (what heroin converts into in the brain),
Dihydroetorphine (Looks like etorphine but EVEN STRONGER - strongest in the etorphine family),
noroxymorphone, (Oxymorphone without a methyl group at the N - 8X morphine potency)
desomorphine, (Morphine without oxygen attached to C-3 and C-6, 8X morphine)
normorphine, (Morphine without a methyl group attached to the N - 1/2Morphine potency)
Metopon, (oxymorphone analog which did not cause physical dependance in monkeys or other primates! Caused mild withdrawals in man, and was abandoned in the 1970s due to an ability to substitute for morphine [euphoric potential])
heterocodeine (despite the name, its 10X morphine - aka 6-O-methyl-morphine),
oxymorphazone - oxymorphone analog which lasts ~48 hours
naltrindole (research antagonist - cool because it looks like a tryptamine attached to an opiate)
nalmefene (antagonist prescribed for those who have liver failure - in the US even),
6-methylene-6-desoxy-dihydromorphinone - Looks like hydromorphone with a Methylene group at the 6 position instead of anything else 80X morphine - mentioned in some college texts

Clandestine:
Alpha Methyl Fentanyl (aka 4-methyl),
Prodine (a meperidine analog - 10X morphine) comes in alpha and beta flavors.
Click to expand...


*Creams his pants* 8o

Metopon, (oxymorphone analog which did not cause physical dependance in monkeys or other primates! Caused mild withdrawals in man, and was abandoned in the 1970s due to an ability to substitute for morphine [euphoric potential])

That sounds very very nice! ;)


No mention of kappa or delta (Any others?) antagonists or is this beta's only?:\
 
kalt_kalt said:
DEXTROMETHORPHAN is NOT an opiate. It is often confused with one because two dimensionally it looks like one. Its stereo-isomer, levomethorphan, IS an opiate (a schedule II one, as well). DXM is also mistakenly considered an opiate because like opiates it reduces the cough reflex. But, it does this in a totally different way than opiates do. The fact that both opiates and DXM do this is a coincidence. DXM is NOT an opiate. Its stereoisomer, however, is.
Click to expand...

...bingo! You are 100% correct.
 
No new LAAM is being made, I think it is available until all of the supply is sold out. I will try and find a link to they story I read, but they are doing it because of the health complications and because it never caught on.
 
sb twelve said:
Tramadol isn't an opiate. It's a non-narcotic pain-killer.
Click to expand...

It nonetheless binds to opiate receptors, and should be included in the list. Plenty of people are addicted to it. . . and plenty enjoy it daily.

This is starting out to be an informative thread, if anyone has comments to make about Tramadol, how much you love/hate it or whatever, ammend one of the current 6,567 threads we already have on it- thanks-

Clonazaman
 
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Its an OPIOID, a synthetic.
call it what you want, narcotics generally mean opiods of any kind. It is wideley disputed its narcotic-state, but either way you look at it, its still an opiod.
Click to expand...
First I'd like to back up my chick *beams with pride at my knowledgeable fiancee*, in saying that while tramadol is not an opiate, it is an opiod, just like Methadone, dextromoramide, fentanyl, all the other fentanyls, and meperidine on this list.

Second, you think you're drooling from that, wait until my E-book comes out... :-)

According to a book I have, "Opiates - Chemistry and Receptors" by Alan F Casy, chemically opiates are those molecules which are structurally derived from morphine, specifically those containing the morphinan ring (1 benzene, 2 other 6-membered rings, such as phenyl) structure. It specifically states that this includes specific isomers of a morphinan.
DEXTROMETHORPHAN would by this definition be an opiate. Pharmacologically it may not be. The word Opiod has 2 different meanings, in 1 sense it is those compounds which share a pharmacological similarity to opiates (activate an opiate receptor - yes even PCP may qualify), and in another sense it is those which are pharmacologically similar AND those which are structurally similar. DEXTROMETHORPHAN only qualifies by the 2nd definition as an opiod.
 
That's from "train-spotting" probably. Some junkie telling his pals that a combination of methadone and "cyclozine" beats everything, even heroin, for euphoria. Cyclozine doesn't exist. He probably means cyclizine - an anti-emetic that was a part of the fabled Diconal - and supposed to add to the methadone high, especially when injected. Brand name Valoid and Marzine. In Britain you get more severe penalties for distributing cyclizine than amphetamine, phenmetrazine etc. I don't know any other country where they rate cyclizine as an addictive drug.

There is also a preparation named cyclazocine, but that's a sort of agonist. I do not think that cyclazocine would enhance any opioid.
 
He probably means cyclizine - an anti-emetic that was a part of the fabled Diconal - and supposed to add to the methadone high, especially when injected.
Click to expand...

no shit? i've never heard of that. you're still missing quite a few on the list...
 
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